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  • Open Access

    ARTICLE

    Effect of Patch Mechanical Properties on Right Ventricle Function Using MRI-Based Two-Layer AnisotropicModels of Human Right and Left Ventricles

    Dalin Tang1, Chun Yang1,2, Tal Geva3,4, Glenn Gaudette4, and Pedro J. del Nido5

    CMES-Computer Modeling in Engineering & Sciences, Vol.56, No.2, pp. 113-130, 2010, DOI:10.3970/cmes.2010.056.113

    Abstract Right and left ventricle (RV/LV) combination models with three different patch materials (Dacron scaffold, treated pericardium, and contracting myocardium), two-layer construction, fiber orientation, and active anisotropic material properties were introduced to evaluate the effects of patch materials on RV function. A material-stiffening approach was used to model active heart contraction. Cardiac magnetic resonance (CMR) imaging was performed to acquire patient-specific ventricular geometries and cardiac motion from a patient with severe RV dilatation due to pulmonary regurgitation needing RV remodeling and pulmonary valve replacement operation. Computational models were constructed and solved to obtain RV stroke volume,… More >

  • Open Access

    ARTICLE

    A Case Study on Mud-Weight Design with Finite-Element Method for Subsalt Wells

    X.P. Shen, A. Diaz1, T. Sheehy2

    CMC-Computers, Materials & Continua, Vol.20, No.3, pp. 205-224, 2010, DOI:10.3970/cmc.2010.020.205

    Abstract This paper presents a case study for the design of a mud-weight window (MWW) with three-dimensional (3-D), finite-element (FE) tools for subsalt wells. The trajectory of the target well penetrates a 7 km thick salt body. A numerical scheme has been proposed for calculating the shear failure gradient (SFG) and fracture gradient (FG) with 3-D FE software. User subroutines have been developed to address non-uniform pore-pressure distribution. A series of FE calculations were performed to obtain the MWW of the target wellbore, which consists of the SFG and FG for the subsalt sections. Although no… More >

  • Open Access

    ARTICLE

    Experimental and Numerical Investigation on the Size of Damage Process Zone of a Concrete Specimen under Mixed-Mode Loading Conditions

    X.P. Shen1, J.L. Feng2

    CMC-Computers, Materials & Continua, Vol.20, No.2, pp. 185-204, 2010, DOI:10.3970/cmc.2010.020.185

    Abstract The characteristic length of a gradient-dependent damage model is a key parameter, which is usually regarded as the length of damage process zone (DPZ). Value and evolution of the size of DPZ were investigated by both a numerical method and an experimental manner. In the numerical study, the geometrical model adopted was a set of four-point shearing beams; the numerical tool used was the Abaqus/Explicit software. The distance between the front and end of a complete DPZ was obtained. Values of strain components at these points were given out at given time points. The experimental… More >

  • Open Access

    REVIEW

    Physiological, ex vivo cell oxygenation is necessary for a true insight into cytokine biology

    Zoran Ivanovic

    European Cytokine Network, Vol.20, No.1, pp. 7-9, 2009, DOI:10.1684/ecn.2009.0144

    Abstract This article has no abstract. More >

  • Open Access

    EDITORIAL

    New insights in the modulation of tumor angiogenesis

    Marco Presta1, Domenico Ribatti2

    European Cytokine Network, Vol.20, No.4, pp. 157-157, 2009, DOI:10.1684/ecn.2009.0171

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    RAPD-determined genetic diversity of Phytophtora cinnamomi Rands of aguacate, Michoacán, Mexico

    Ochoa-Fuentes YM1, E Cerna2, J Landeros2, O Vazquez1, V Olalde3, A Flores2

    Phyton-International Journal of Experimental Botany, Vol.78, pp. 25-30, 2009, DOI:10.32604/phyton.2009.78.025

    Abstract Forty two Mexican isolates of Phytophthora cinnamomi Rands were examined for genetic diversity by the random amplified polymorphic DNA assay. The amount of genetic variation was evaluated by polymerase chain reaction amplification with a set of twenty one random 10-mer primers. All amplifications revealed scorable polymorphisms among the isolates, and a total of 23 band positions were scored for the 21 primers tested. Genetic distances among the isolates were calculated, and cluster analysis was used to generate a dendogram which showed relationships between them. These results suggest that the geographic groups were strong. More >

  • Open Access

    ABSTRACT

    Mechanical insights into the physiological functions of intercellular adhesion proteins

    S.R.K Vedula1, T.S. Lim2, W. Hunziker3, C.T. Lim1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.13, No.1, pp. 29-30, 2009, DOI:10.3970/icces.2009.013.029

    Abstract The structural integrity as well as the regulation of paracellular diffusion of solutes across epithelial monolayers is critically regulated by the intercellular adhesion complex. The intercellular adhesion complex consists of a variety of proteins that perform different physiological functions. While proteins localizing at adherens junctions (nectins and e-cadherins) are important for initiating and stabilizing cell adhesion, proteins localizing at the tight junctions (occludin, claudins and junctional adhesion molecules) act as gates to regulate the diffusion of solutes across the epithelial monolayer. Despite significant advancement in the understanding of the biological roles of these cell adhesion More >

  • Open Access

    ABSTRACT

    Characterization of impact resistance of lightweight aggregate cellular concretes (LACC)

    Eun A Hwang1, Haeng-Ki Lee1, Jong Won Kwark2, Jung Woo Lee2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.12, No.1, pp. 11-12, 2009, DOI:10.3970/icces.2009.012.011

    Abstract Concrete structures such as concrete safety barriers are often subjected to direct impact loads mainly due to vehicle crash impact. In this case, the impact resistance is one of the most critical characteristic of concrete used in such structures. The present study aims to characterize the impact resistance of lightweight aggregate cellular concrete (LACC), which will be used in concrete barriers. Impact tests on LACC specimens were carried out based on the repeated drop-weight impact test guideline recommend by ACI committee 544. Impact resistance and compressive strength of the LACC specimens were characterized and the More >

  • Open Access

    ABSTRACT

    Dislocations analysis of silicon crystal through action-derived molecular dynamics with tight-binding method

    Youngmin Lee, Jae Shin Park, Seyoung Im

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.10, No.2, pp. 51-52, 2009, DOI:10.3970/icces.2009.010.051

    Abstract We study energetics and mobility of dislocations in silicon crystal in atomistic scale. The electronic structure of silicon affects its dynamics, so that it is analyzed with tight-binding method for high accuracy, emerged as a useful method for studying structural and dynamical properties of covalent systems. The tight biding potential used for silicon crystalline is the one of GSP known as a transferable potential. Due to the nature of rare events, the analysis is executed by action-derived molecular dynamics (ADMD) calculations. The changes of the system energy due to dislocation glide are explored with a More >

  • Open Access

    ABSTRACT

    A study of HID light reflector design of a streetlight

    Shy-Pin Cuo1, Dein Shaw2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.9, No.3, pp. 199-200, 2009, DOI:10.3970/icces.2009.009.199

    Abstract The purpose of this study is to present the process of development of HID (High Intensity Discharge) light reflector of a streetlight. The new application of HID light source for streetlight product is proposed in this study, the advantages of HID include low power consumption and single point light source emitting. The study includes the introduction of HID streetlight structure, the lighting efficiency comparison of various light sources (ex. High Pressure Sodium-lamp ``HPS'', High Bright LED ``HB LED'', etc\ldots ), and the design of streetlight reflector. The emphases of the experiment are focused at light… More >

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