Elise D. Pieterman^1,2, Ricardo P. J. Budde², Danielle Robbers-Visser^1,2, Ron T. van Domburg³, Willem A. Helbing^1,2

Congenital Heart Disease, Vol.12, No.5, pp. 561-569, 2017, DOI:10.1111/chd.12484

Abstract Objective: Follow-up of right ventricular performance is important for patients with congenital heart disease. Cardiac magnetic resonance imaging is optimal for this purpose. However, observerdependency of manual analysis of right ventricular volumes limit its use. Knowledge-based reconstruction is a new semiautomatic analysis tool that uses a database including knowledge of right ventricular shape in various congenital heart diseases. We evaluated whether knowledge-based reconstruction is a good alternative for conventional analysis.
Design: To assess the inter- and intra-observer variability and agreement of knowledge-based versus conventional analysis of magnetic resonance right ventricular volumes, analysis was done by two observers… More >

Chih-Hsin Hsu^1,2, Jun-Neng Roan^1,3, Jieh-Neng Wang⁴, Chien-Chi Huang⁵, Chao-Jung Shih³, Jyh-Hong Chen^2,6, Jing-Ming Wu⁴, Chen-Fuh Lam^7,8

Congenital Heart Disease, Vol.12, No.4, pp. 533-539, 2017, DOI:10.1111/chd.12479

Abstract Objectives: Atrial septal defects may result in pulmonary hypertension and right heart remodeling. We analyzed improvements in patients with flow-induced pulmonary hypertension and the activation of endothelial progenitor cells after flow reduction.
Design: This prospective cohort study included 37 patients who were admitted for an occluder implantation. Blood samples were collected before and after the procedure. We determined the number of endothelial progenitor cells in outgrowth colonies and serum Hsp27 concentrations. Daily performance and cardiothoracic ratio were reevaluated later.
Results: Closure of the defect significantly reduced the pulmonary pressure and B-type natriuretic peptide levels. The cardiothoracic ratio and… More >

Magalie Ladouceur^1,2,3, Nadjia Kachenoura⁴, Gilles Soulat^1,3, Emilie Bollache⁴, Alban Redheuil⁴, Michel Azizi³, Christophe Delclaux³, Gilles Chatellier³, Pierre Boutouyrie^1,3, Laurence Iserin³, Damien Bonnet^2,3, Elie Mousseaux^1,3

Congenital Heart Disease, Vol.12, No.4, pp. 458-466, 2017, DOI:10.1111/chd.12472

Abstract Objectives: We aimed (1) determine if systemic right ventricle filling parameters influence systemic right ventricle stroke volume in adult patients with D-transposition of the great arteries (D-TGA) palliated by atrial switch, using cardiac magnetic resonance imaging and echocardiography, and (2) to study relationship of these diastolic parameters with exercise performance and BNP, in patients with preserved systolic systemic right ventricle function.
Design: Single-center, cross-sectional, prospective study.
Setting: In patients with D-TGA palliated by atrial switch, diastolic dysfunction of the systemic right ventricle may precede systolic dysfunction.
Methods: Forty-five patients with D-TGA and atrial switch and 45 age and sex-matched… More >

Kari L. Turkowski¹, David J. Tester^2,3, J. Martijn Bos^2,4, Kristina H. Haugaa⁵, Michael J. Ackerman^2,3,4

Congenital Heart Disease, Vol.12, No.2, pp. 226-235, 2017, DOI:10.1111/chd.12462

Abstract Background: Arrhythmogenic cardiomyopathy (ACM) is a heritable disease characterized by fibrofatty replacement of cardiomyocytes, has a prevalence of approximately 1 in 5000 individuals, and accounts for approximately 20% of sudden cardiac death in the young (≤35 years). ACM is most often inherited as an autosomal dominant trait with incomplete penetrance and variable expression. While mutations in several genes that encode key desmosomal proteins underlie about half of all ACM, the remainder is elusive genetically. Objective: Here, whole exome sequencing (WES) was performed with genomic triangulation in an effort to identify a novel explanation for a… More >

Xie LB¹, X Wang¹, M Peng², Y Zhou¹, LX Chen¹, LX Liu³, YL Gao¹, YH Guo¹

Phyton-International Journal of Experimental Botany, Vol.86, pp. 236-245, 2017, DOI:10.32604/phyton.2017.86.236

Abstract Hot pepper (Capsicum annuum L.) is an important crop all over the world. To explore and identify differentially expressed proteins of hot pepper after space flight, three space-induced mutants (Y1, Y2 and Y3), which obtained new traits after space flight compared with their control lines (W1 and W2), were analyzed using comparative proteome analysis. In this study, leaf morphological characteristics of five kinds of hot pepper variations were evaluated by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Results showed that obvious changes of cellular structure were seen in space induced mutants. Thirty nine out More >

Ataei R¹, M Gholamhoseini¹, M Kamalizadeh²

Phyton-International Journal of Experimental Botany, Vol.86, pp. 228-235, 2017, DOI:10.32604/phyton.2017.86.228

Abstract Understanding the genetic control of traits associated with yield helps breeders to utilize their germplasm in a more efficient and consistent manner and to make good choices in breeding programs. The current study was carried out to study the genetic control of some quantitative traits in bread wheat (Triticum aestivum L.) and to examine plant responses under full irrigation and drought stress conditions. For this purpose, six generations derived from a cross between two lines (Bezostaya as tolerant parent and 518 as a susceptible parent) were evaluated for grain yield (GY), plant height (PH), peduncle (PL)… More >

Castañón-Nájera G¹, L Latorunerie-Moreno², YA Gálvez Muñoz³

Phyton-International Journal of Experimental Botany, Vol.86, pp. 290-295, 2017, DOI:10.32604/phyton.2017.86.290

Abstract Among the different types of abiotic stresses, water is the most damaging for crops. In the current research, the effect of water stress, induced with Polyethylene Glycol 8000 (PEG8000) and Sodium chloride (NaCl) solutions, was studied in maize genotypes. A randomized block design (RBD) with a factorial arrangement and four replications of 25 seeds each was used. The studied maize genotypes were RC₂C39, RC₂C51 (wild varieties of the State of Tabasco backcrossed with the endogamic line CML247 of the International Center for the Improvement of Maize and Wheat), wild Tamulte, VS536, and Asgrow 7573 hybrid, study… More >

Dalin Tang^1,*,2, Heng Zuo^2,*, Chun Yang², Zheyang Wu², Xueying Huang³, Rahul H. Rathod⁴, Alexander Tang⁴, Kristen L. Billiar⁵, Tal Geva⁴

Molecular & Cellular Biomechanics, Vol.14, No.3, pp. 137-151, 2017, DOI:10.3970/mcb.2017.014.137

Abstract Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle failure. Comparing TOF patients with healthy people may provide information to address this challenge. Cardiac magnetic resonance (CMR) data were obtained from 16 TOF patients (patient group, PG) and 6 healthy volunteers (healthy group, HG). At begin-of-ejection, better patient group (n=5, BPG) stress was very close to HG stress (54.7±38.4 kPa vs. 51.2±55.7 kPa, p=0.6889) while worse patient group (n=11, WPG) stress was 84% higher than HG stress (p=0.0418). Stress may be used as an indicator to differentiate More >

Costas D. Lallas

Canadian Journal of Urology, Vol.23, No.1, pp. 8167-8167, 2016

Abstract This article has no abstract. More >

Thomas W. Jarrett

Canadian Journal of Urology, Vol.23, No.1, pp. 8115-8115, 2016

Abstract This article has no abstract. More >