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  • Open Access

    ARTICLE

    Influence of a high carbohydrate diet on the functional activity of 5-HT1B/1D receptors on human peripheral blood lymphocytes during intense military training

    Mounir Chennaoui, Catherine Drogou, Charles-Yannick Guezennec, Danielle Gomez-Merino

    European Cytokine Network, Vol.17, No.1, pp. 67-74, 2006

    Abstract The present study was undertaken to examine the effect of a high carbohydrate diet on the functional activity of 5-HT1B/1D receptors in human peripheral blood lymphocytes, and on serum cortisol and plasma cytokine responses during intense military training. Thirty two male soldiers (mean age: 21 ± 2 years) were randomly assigned to two groups and received either 3200 kcal/24 h [13440 kJ; habitual diet group (HD)] or 4200 kcal/24 h [17640 kJ, high carbohydrate diet group (HCD)] by adding 1000 kcal (4200 kJ) of fruit jelly to the HD. They took part in a three-week training… More >

  • Open Access

    ARTICLE

    Association of the IL6-174(G/C) polymorphism with C-reactive protein concentration after weight loss in obese men

    Carita Eklund1, Arja Nenonen2,3,4, Katriina Kukkonen-Harjula3, Patrik Borg3, Mikael Fogelholm3,5, Seppo Laine6, Heini Huhtala7, Terho Lehtimäki4, Mikko Hurme1,8

    European Cytokine Network, Vol.17, No.2, pp. 131-135, 2006

    Abstract Elevated plasma concentration of C-reactive protein has emerged as an important predictor of future cardiovascular diseases and metabolic abnormalities in apparently healthy individuals. Obese individuals tend to have elevated C-reactive protein concentrations. Weight loss induces a change in this protein, and single nucleotide polymorphisms in regulating genes might affect this change, since C-reactive protein concentration is known to be approximately 40-50% heritable. Our aim was to study the association between the IL6 -174(G/C), IL1B +3954(C/T) and CRP +1059(G/C) single nucleotide polymorphisms, and CRP concentrations in obese men during a weight reduction program. We genotyped 72… More >

  • Open Access

    ARTICLE

    Genetic polymorphisms for vascular endothelial growth factor in perinatal complications

    Ilona Bányász1, Géza Bokodi1, Barna Vásárhelyi2, András Treszl1, László Derzbach1, András Szabó1, Tivadar Tulassay1,2,3, Ádám Vannay3

    European Cytokine Network, Vol.17, No.4, pp. 266-270, 2006, DOI:10.1684/ecn.2006.0041

    Abstract Low birth weight (LBW) infants have increased susceptibility to perinatal complications. An immature and impaired vascular system may possibly participate in these complications. There is evidence that supports the notion that vascular endothelial growth factor (VEGF), which is an essential regulator of embryonic angiogenesis, plays a central role in the pathogenesis of perinatal complications. We aimed to test whether functional genetic polymorphisms of VEGF are associated with the risk of preterm birth or perinatal morbidity. We enrolled 128 LBW infants (≤ 1500 grams). VEGF T-460C, VEGF C-2578A and VEGF G+405C polymorphisms were determined by real-time… More >

  • Open Access

    ARTICLE

    Expression of human telomerase reverse transcriptase, Suroivin, DD3 and PCGEM1 messenger RNA in archival prostate carcinoma tissue

    Hanna Bialkowska-Hobrzanska, David K. Driman, Robert Fletcher, Vimla Harry, Hassan Razvi

    Canadian Journal of Urology, Vol.13, No.1, pp. 2967-2974, 2006

    Abstract Background: The variable clinical behavior displayed by prostate cancer (PCa) warrants investigation of potential PCa-specific biomarkers that could identify more aggressive tumor types and therefore provide prognostic value. Upregulation of expression of human telomerase reverse transcriptase (hTERT), Survivin, DD3 and PCGEM1 mRNAs in PCa lesions has recently been described. The purpose of this study was to evaluate the clinical value of detection of overexpression of these biomarkers in the diagnosis and prognosis of PCa.
    Material and methods: Archival formalin-fixed, paraffin-embedded (FFPE) prostatectomy tissue from 26 patients with PCa (Gleason score 3-9, mean 7) and 14 patients with… More >

  • Open Access

    ABSTRACT

    Supplement. 16 Symposium: BIOLOGY AND CULTURE OF SILVERSIDES (PEJERREYES) A standard weight equation to assess the body condition of pejerrey Odontesthes bonariensis

    DARÍO C. COLAUTTI1,2, MAURICIO REMES LENICOV1,3, GUSTAVO E. BERASAIN1

    BIOCELL, Vol.30, Suppl.S, pp. 131-135, 2006

    Abstract We developed a standard weight equation Ws to aid in the analysis of pejerrey Odonthestes bonariensis body condition over time and across populations using the relative weight index Wr. Weight length data were compiled from 73 populations of pejerrey (N=16.022) from the Argentine pampas region. We used the regression-line-percentile technique, which provides a 75th-percentile standard by length intervals of 10 mm, to develop the Ws equation. The proposed equation is log10 Ws=-5,267+3,163 log10 Lst; Ws is weight in grams and Lst is standard length in millimeters. This equation is proposed for use with pejerrey between 120 and… More >

  • Open Access

    ABSTRACT

    Supplement. 6 Workshop: Biology of Ampullariidae Biochemical composition, tissue origin and functional properties of egg perivitellins from Pomacea canaliculata

    MARCOS S. DREON1, HORACIO HERAS1,2, RICARDO J. POLLERO1

    BIOCELL, Vol.30, Suppl.S, pp. 359-365, 2006

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    The Application of a Hybrid Inverse Boundary Element Problem Engine for the Solution of Potential Problems

    S. Noroozi1, P. Sewell1, J. Vinney1

    CMES-Computer Modeling in Engineering & Sciences, Vol.14, No.3, pp. 171-180, 2006, DOI:10.3970/cmes.2006.014.171

    Abstract A method that combines a modified back propagation Artificial Neural Network (ANN) and Boundary Element Analysis (BEA) was introduced and discussed in the author's previous papers. This paper discusses the development of an automated inverse boundary element problem engine. This inverse problem engine can be applied to both potential and elastostatic problems.
    In this study, BEA solutions of a two-dimensional potential problem is utilised to test the system and to train a back propagation Artificial Neural Network (ANN). Once training is completed and the transfer function is created, the solution to any subsequent or new… More >

  • Open Access

    ARTICLE

    Spectral Element Approach for Forward Models of 3D Layered Pavement

    Chun-Ying Wu1,3, Xue-Yan Liu2, A. Scarpas2, Xiu-Run Ge3

    CMES-Computer Modeling in Engineering & Sciences, Vol.12, No.2, pp. 149-158, 2006, DOI:10.3970/cmes.2006.012.149

    Abstract For the spectral analysis of the three-dimensional multi-layered pavement, 3D layer spectral element method is presented to solve the problems of bounded layer system subjected to a transient load pulse. In spectral element, each layer is treated as one spectral element. The wave propagation inside each layer element is achieved by the superposition of the incident wave and the reflection wave. Fast Fourier transformation is used to transform FWD datum from time domain to frequency domain. The accuracy and efficiency of 3D layer spectral element approach were verified by analyzing the Falling weight deflectometer(FWD) testing More >

  • Open Access

    ARTICLE

    The Optimal Radius of the Support of Radial Weights Used in Moving Least Squares Approximation

    Y.F. Nie1,2, S.N. Atluri2, C.W. Zuo1

    CMES-Computer Modeling in Engineering & Sciences, Vol.12, No.2, pp. 137-148, 2006, DOI:10.3970/cmes.2006.012.137

    Abstract Owing to the meshless and local characteristics, moving least squares (MLS) methods have been used extensively to approximate the unknown function of partial differential equation initial boundary value problem. In this paper, based on matrix analysis, a sufficient and necessary condition for the existence of inverse of coefficient matrix used in MLS methods is developed firstly. Then in the light of approximate theory, a practical mathematics model is posed to obtain the optimal radius of support of radial weights used in MLS methods. As an example, while uniform distributed particles and the 4th order spline weight More >

  • Open Access

    ARTICLE

    Numerical Simulation of Dynamic Elasto Visco-plastic Fracture Using Moving Finite Element Method

    T. Fujimoto1 and T. Nishioka1

    CMES-Computer Modeling in Engineering & Sciences, Vol.11, No.2, pp. 91-102, 2006, DOI:10.3970/cmes.2006.011.091

    Abstract In the dynamic fracture of metallic material, some cracks propagate with the incidence of plastic deformation, and distinct plastic strain remains near the post-propagation area. In order to elucidate these dynamic nonlinear fracture processes, the moving finite element method is developed for nonlinear crack propagation. The T* integral is used as the parameter to estimate crack tip condition. First, the effect of material viscosity and crack propagation velocity have been discussed based on the numerical results for fracture under pure mode I high speed loading. Under mixed mode loading, numerical simulations for fracture path prediction More >

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