Abhishek Karnwal1, Rose Venegas2, Brian Shuch1,3, Jeffrey Bassett1,3, Jacob Rajfer1,3, Richard Reznichek1,3
Canadian Journal of Urology, Vol.17, No.2, pp. 5077-5081, 2010
Abstract Objective: To compare the sensitivity and specificity of UroVysion fluorescence in situ hybridization assay (FISH) with cystoscopy and urine cytology in the surveillance of patients with documented non-muscle invasive bladder cancer (CIS, pTa and pT1).
Methods: This retrospective study was done on a consecutive series of patients undergoing surveillance for non-muscle invasive bladder cancer. The results of FISH were analyzed with concurrent cystoscopy and urine cytology.
Results: In all, 94 follow up visits from 59 patients were evaluated. The mean follow up was 52 months. FISH detected 30/48 recurrences of bladder cancer, as compared to 20/48 for cytology… More >