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  • Open Access

    ARTICLE

    On the Modeling of Non-Classical Problems Involving Liquid Jets and Films and Related Heat Transfer Processes

    Ivan V. Kazachkov1,2,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.15, No.5, pp. 491-507, 2019, DOI:10.32604/fdmp.2019.06477

    Abstract Non-classical subjects relating to the dynamics of jet and film flow and related heat transfer processes are considered. These problems, which are relevant to several technological applications, cannot completely be addressed in the frame of the canonical Navier-Stokes equations. The first example deals with the formation of a film flow as a result of the hydraulic shock of a vertical jet impinging on a horizontal plane. The effective thickness of the film resulting from the hydraulic shock is much less than the value obtained using the conventional approach (relying on the assumption of smooth flow),… More >

  • Open Access

    ARTICLE

    Unsteady MHD Free Convective Flow Past a Vertical Porous Plate with Span-Wise Fluctuating Heat and Mass Transfer Effects

    S . Samantha Kumari1,*, G. Sankara Sekhar Raju2

    FDMP-Fluid Dynamics & Materials Processing, Vol.15, No.5, pp. 471-489, 2019, DOI:10.32604/fdmp.2019.04222

    Abstract This paper investigates the chemical reaction and thermal radiation effects on unsteady MHD free convective flow past a vertical porous plate in the presence of heat absorption/generation. The novelty of present investigation is that the temperature and concentration of the plate are span wise cosinusoidally unsteady with time. The second order perturbation technique is employed to study the non-linear partial differential equations which govern the fluid flow. The effects of magnetic parameter, radiation, Eckert number, Schmidt number and chemical reaction parameters on velocity, temperature and concentration distributions as well as skin friction coefficients, the rate More >

  • Open Access

    ARTICLE

    Association of TRIM22 with the type 1 interferon response during primary human cytomegalovirus infection in THP-1 macrophages

    Wei LI, Huihui GAO, Ran TAO, Lifang LIU, Shiqiang SHANG*

    BIOCELL, Vol.43, No.4, pp. 285-291, 2019, DOI:10.32604/biocell.2019.08177

    Abstract As a response factor of interferon, tripartite motif (TRIM) 22 was reported to exert antiviral activity against viruses. In this study, THP-1 macrophages were infected with human cytomegalovirus (HCMV) to establish the HCMV lytic infection model. The mRNA levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and interferonbeta (IFN-β) were significantly up-regulated in THP-1 macrophages at different infection time and titers. Moreover, for the first time, upregulation of TRIM22 expression was found during HCMV infection at both mRNA and protein levels in THP-1 macrophages. Furthermore, IFN-β could induce TRIM22 expression in THP-1 macrophages or HCMV More >

  • Open Access

    ARTICLE

    Retrieval, reporting and methodological characteristics for systematic reviews/meta-analyses of animal models: a meta-epidemiological study

    Shuzhen SHI1, 2, Ming LIU1, 2, Wenjuan MA1, 2, Ya GAO1, 2, Long GE3, Xiping SHEN3, Jiarui WU4, Junhua ZHANG5, *, Jinhui TIAN1, 2, *

    BIOCELL, Vol.43, No.4, pp. 233-251, 2019, DOI:10.32604/biocell.2019.07624

    Abstract The study aimed to analyze the reporting and methodological quality of systematic reviews (SRs)/metaanalyses (MAs) of animal models to provide references for later studies and avoid the waste of medical resources. EMBASE and MEDLINE databases were searched from inception to November 2017, with no language restriction. Two reviewers selected inclusion dependently and extracted the basic characteristics. Review Manager 5.3, stata 12.0, and SPSS 21 software were used to conduct analyses. A total of 46 SRs/MAs were included. The results showed that the English databases with high retrieval frequency are PubMed/MEDLINE, EMBASE, and Web of Science.… More >

  • Open Access

    ARTICLE

    Numerical Simulation of Debris Flow Runout Using Ramms: A Case Study of Luzhuang Gully in China

    Jianjun Gan1,2, Y. X. Zhang2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.3, pp. 981-1009, 2019, DOI:10.32604/cmes.2019.07337

    Abstract This study proposes a comprehensive method, which consists of field investigation, flume test and numerical simulation, to predict the velocity and sediment thickness of debris flow. The velocity and sediment thickness of the debris flow in mountainous areas can provide critical data to evaluate the geohazard, which will in turn help to understand the debris runout. The flume test of this debris prototype can provide friction coefficient and viscosity coefficient which are important for numerical simulation of debris flow. The relation between the key parameters in the numerical modelling using the Voellmy model and debris-flow More >

  • Open Access

    ARTICLE

    Geometrically Nonlinear Analysis of Structures Using Various Higher Order Solution Methods: A Comparative Analysis for Large Deformation

    Ali Maghami1, Farzad Shahabian1, Seyed Mahmoud Hosseini2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.3, pp. 877-907, 2019, DOI:10.32604/cmes.2019.08019

    Abstract The suitability of six higher order root solvers is examined for solving the nonlinear equilibrium equations in large deformation analysis of structures. The applied methods have a better convergence rate than the quadratic Newton-Raphson method. These six methods do not require higher order derivatives to achieve a higher convergence rate. Six algorithms are developed to use the higher order methods in place of the NewtonRaphson method to solve the nonlinear equilibrium equations in geometrically nonlinear analysis of structures. The higher order methods are applied to both continuum and discrete problems (spherical shell and dome truss).… More >

  • Open Access

    REVIEW

    Review on Application of Artificial Intelligence in Civil Engineering

    Youqin Huang1, Jiayong Li1, Jiyang Fu1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.3, pp. 845-875, 2019, DOI:10.32604/cmes.2019.07653

    Abstract In last few years, big data and deep learning technologies have been successfully applied in various fields of civil engineering with the great progress of machine learning techniques. However, until now, there has been no comprehensive review on its applications in civil engineering. To fill this gap, this paper reviews the application and development of artificial intelligence in civil engineering in recent years, including intelligent algorithms, big data and deep learning. Through the work of this paper, the research direction and difficulties of artificial intelligence in civil engineering for the past few years can be More >

  • Open Access

    ARTICLE

    Effect of the Wall Thickness of the Vessel on FFRCT of Carotid Artery Stenosis

    Long Yu1, Kesong Xu1, Jun Wan2, Haiyan Lu3,*, Shengzhang Wang1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.3, pp. 835-844, 2019, DOI:10.32604/cmes.2019.07428

    Abstract Fractional flow reserve (FFR) computed from computed tomography angiography (CTA), i.e., FFRCT has been used in the clinic as a noninvasive parameter for functional assessment of coronary artery stenosis. It has also been suggested to be used in the assessment of carotid artery stenosis. The wall thickness of the vessel is an important parameter when establishing a fluid-structure coupling model of carotid stenosis. This work studies the effect of the vessel wall thickness on hemodynamic parameters such as FFRCT in carotid stenosis. Models of carotid stenosis are established based on CTA image data using computer-aided design… More >

  • Open Access

    ARTICLE

    Stability Analysis of Cyber-Physical Micro Grid Load Frequency Control System with Time-Varying Delay and Non-Linear Load Perturbations

    D. Vijeswaran1,*, V. Manikandan2

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.3, pp. 801-813, 2019, DOI:10.32604/cmes.2019.07793

    Abstract In a cyber-physical micro-grid system, wherein the control functions are executed through open communication channel, stability is an important issue owing to the factors related to the time-delay encountered in the data transfer. Transfer of feedback variable as discrete data packets in communication network invariably introduces inevitable time-delays in closed loop control systems. This delay, depending upon the network traffic condition, inherits a time-varying characteristic; nevertheless, it adversely impacts the system performance and stability. The load perturbations in a micro-grid system are considerably influenced by the presence of fluctuating power generators like wind and solar… More >

  • Open Access

    ARTICLE

    Computational Study of Collective Cell Migration By Meshfree Method

    Jie Bai1,#, Liqiang Lin1,#, Xiaowei Zeng 1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.3, pp. 787-800, 2019, DOI:10.32604/cmes.2019.07159

    Abstract The collective cell migration behavior on a substrate was studied using RKPM meshfree method. The cells were modeled as nematic liquid crystal with hyperelastic cell nucleus. The cell-substrate and cell-cell interactions were modeled by coarse-grained potential forces. Through this study, the pulling and pushing phenomenon during collective cell migration process was observed and it was found that the individual cell mobility significantly influenced the collective cell migratory behavior. More self-propelled cells are in the system along the same direction, the faster the collective group migrates toward coordinated direction. The parametric study on cell-cell adhesion strength More >

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