Josep M. Gaya^1,2, Justin Matulay¹, Gina M. Badalato¹, Dara D. Holder¹, Gregory Hruby¹, James McKiernan¹

Canadian Journal of Urology, Vol.21, No.2, pp. 7228-7233, 2014

Abstract Introduction: Involvement of the prostatic urethra by bladder cancer directly impacts prognosis, risk of urethral recurrence, and timing of radical cystectomy (RC); it also affects the type of urinary diversion chosen. Both cold cup biopsies and transurethral (TUR) loop biopsies have been used to evaluate the status of the prostatic urethra. We report our 20 year experience with preoperative and intraoperative prostatic urethral biopsies to determine relative efficacy and associated treatment implications.
Materials and methods: The Columbia University urologic oncology database was reviewed and yielded 234 men who underwent preoperative endoscopic biopsies of the prostatic urethra… More >

Anup Vora, Daniel Marchalik, Hanaa Nissim, Keith Kowalczyk, Gaurav Bandi, Kevin McGeagh, John Lynch, Krishnan Venkatesan, Reza Ghasemian, Jonathan Hwang, Mohan Verghese

Canadian Journal of Urology, Vol.21, No.2, pp. 7222-7227, 2014

Abstract Introduction: Radical cystectomy is associated with significant morbidity and cost, with rates of gastrointestinal complications as high as 30%. Alvimopan is a mu opioid receptor antagonist that has been shown in randomized-control trials to accelerate gastrointestinal recovery in patients undergoing bowel resection with primary anastamosis. We report our experience with gastrointestinal recovery for patients undergoing cystectomy with urinary diversion treated with alvimopan and cost benefit associated.
Materials and methods: Between January 2008 and October 2012, 80 patients underwent radical cystectomy with urinary diversion at two institutions. Forty-two patients in our study did not receive alvimopan preoperatively.… More >

Bilal Chughtai¹, Claire Dunphy¹, Richard Lee¹, Daniel Lee¹, Seema Sheth¹, Leonard Marks², Steven A. Kaplan¹, Alexis E. Te¹

Canadian Journal of Urology, Vol.21, No.2, pp. 7217-7221, 2014

Abstract Introduction: We assessed the efficacy of onabotulinumtoxinA (Botox, Allergan Inc., Irvine, CA, USA) in patients with refractory overactive bladder (OAB) after treatment for benign prostatic hyperplasia (BPH).
Materials and methods: This was a two-center, randomized, double-blinded pilot study conducted in patients with OAB secondary to bladder outlet obstruction (BOO), refractory to anticholinergic medication and persistent for greater than 3 months after surgical intervention to relieve obstruction, with an International Prostate Symptom Score (IPSS) >12. Patients were randomized in 1:1 fashion to either 200 units of onabotulinumtoxinA versus placebo. Fifteen patients received onabotulinumtoxinA versus 13 who received… More >

Guido Giusti¹, Silvia Proietti¹, Lorenzo G. Luciani², Roberto Peschechera¹, Antonella Giannantoni³, Gianluigi Taverna¹, Giuseppe Sortino^1,4, Pierpaolo Graziotti¹

Canadian Journal of Urology, Vol.21, No.2, pp. 7207-7212, 2014

Abstract Introduction: Major kidney stones have traditionally been treated with percutaneous nephrolithotomy. However, retrograde intrarenal surgery (RIRS), which until a few years ago was considered inappropriate for this purpose, is becoming a viable, attractive alternative. The aim of the current study was to assess the efficacy and safety of RIRS combined with holmium laser lithotripsy for the treatment of stones >2 cm in diameter in a large series of patients, reporting complications according to the Clavien-Dindo classification.
Materials and methods: By retrospective analysis, we identified a total of 162 patients who were affected by stones greater than… More >

Gregory Wade¹, Stanley Zaslau², Robert Jansen²

Canadian Journal of Urology, Vol.21, No.2, pp. 7179-7184, 2014

Abstract Introduction: Urinary fistulae develop as abnormal connections between the gastrointestinal (GI) and genitourinary (GU) tracts, and occur in multiple disease processes including diverticulitis, malignancy, and Crohn’s disease. Crohn’s disease is now the most common cause of fistula formation between the ileum and bladder and the third most common cause of fistulae between the colon and the bladder. Few articles provide a comprehensive review of this process.
Materials and methods: We performed a PubMed search using such terms as “fistula” and “Crohn’s disease” and/or “enterovesical fistula.” We reviewed references from selected papers and relevant articles were used for… More >

Fernando J. Kim^1,2, Priya N. Werahera³, David E. Sehrt¹, Diedra Gustafson¹, Rodrigo D. Silva¹, Wilson R. Molina¹

Canadian Journal of Urology, Vol.21, No.3, pp. 7305-7311, 2014

Abstract Introduction: Our safety net hospital offers minimally invasive, traditional open and perineal radical prostatectomies, as well as radiation therapy and medical oncological services when appropriate. Historically, only few African American and Hispanic patients elected surgical procedures due to unknown reasons. Interestingly, after initiation of the prostate cryoablation program (Whole Gland) in 2003 at Denver Health Medical Center (DHMC) we noticed a trend towards cryotherapy in these specific patient populations for the treatment of localized prostate cancer. We analyzed the profile of ethnic minority men evaluated for localized prostate cancer and evaluated the associated factors in the… More >

Yun-Sok Ha^1,2, Dong Il Kang³, Jeong Hyun Kim⁴, Jae Young Joung⁵, Jihyeong Yu⁶, Jaspreet S. Parihar¹, Amirali Hassanzadeh Salmasi¹, Shigeo Horie⁷, Wun-Jae Kim⁸, Isaac Yi Kim¹

Canadian Journal of Urology, Vol.21, No.3, pp. 7290-7297, 2014

Abstract Introduction: Positive surgical margin (PSM) has classically been associated with biochemical recurrence (BCR) following radical prostatectomy (RP) and immediate adjuvant radiotherapy has been advocated based on two large randomized prospective clinical studies. However, a significant percentage of patients with PSM never experience BCR. This study evaluated factors potentially affecting risk of BCR among the patients with PSM after robot-assisted radical prostatectomy (RARP).
Materials and methods: From a prospectively maintained database, 699 patients with localized prostate cancer who underwent a RARP without any adjuvant therapy were identified. Median follow up was 46.0 months. To determine the pathologic and… More >

Casey Kowalik, Jason R. Gee, Andrea Sorcini, Alireza Moinzadeh, David Canes

Canadian Journal of Urology, Vol.21, No.3, pp. 7266-7270, 2014

Abstract Introduction: A single perioperative dose of intravesical chemotherapy (IVC) following transurethral resection of bladder tumors (TURBT) for non-muscle invasive bladder cancer has demonstrated a reduction in tumor recurrence. In this study, we investigate the contemporary (2010) utilization of IVC following TURBT using a prospective national database.
Materials and methods: Using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database, we identified patients with bladder cancer using ICD-9 codes. From this group, patients undergoing TURBT based on Current Procedural Terminology (CPT) codes were analyzed. We then identified those patients who underwent TURBT and also received… More >

Mark D. Tyson II¹, Alan H. Bryce², Thai H. Ho², Estrella M. Carballido², Erik P. Castle¹

Canadian Journal of Urology, Vol.21, No.3, pp. 7259-7265, 2014

Abstract Introduction: Few data on the perioperative outcomes of cystectomy after neoadjuvant chemotherapy (NAC) exist. In this study, we evaluated whether patients who had previously received NAC were at higher risk of developing perioperative complications.
Materials and methods: The National Surgical Quality Improvement Program (NSQIP) database was searched to identify cystectomies performed between January 1, 2005 and December 31, 2011. Of 1394 patients identified, about one-tenth (n = 122 [8.8%]) received NAC. A propensity-weighted comparative analysis of perioperative morbidity was conducted.
Results: In unadjusted comparisons, patients undergoing cystectomy after NAC were more likely to have peripheral nerve deficits (1.6%… More >

Leonard G. Gomella

Canadian Journal of Urology, Vol.21, No.3, pp. 7255-7255, 2014

Abstract This article has no abstract. More >