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  • Open Access

    ABSTRACT

    Contribution as for the Optimization of the Pumping Stations

    A. Alexenadrescu1, A.S. Alex,rescu1, A.C. Alexandrescu1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.8, No.2, pp. 47-58, 2008, DOI:10.3970/icces.2008.008.047

    Abstract The paper follows the analyse of the connections between the constructive, working parameters, the annual energy consumptions and the energy quantity included in fitting out; it will formulate a methodology of establishment of the optimum values of the parameters of admeasurements of the pumping stations for the setting under pressure, of pipes networks, what ensure an optimum consumption of energy during of duty of the fitting out (the operational energy and the included energy in the networks, equipment and constructions), of the conditions after that it can be obtained. It will follow the generalization of More >

  • Open Access

    ABSTRACT

    Physiological Cost Optimization for Bipedal Modeling with Optimal Controller Design

    A. M. Mughal1, K. Iqbal2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.6, No.4, pp. 215-220, 2008, DOI:10.3970/icces.2008.006.215

    Abstract Human voluntary movements are complex physical phenomenon and there are several physiological factors that control the movement and transient response, steady state position, speed of motion and other characteristics. Many experimentalists described variety of variables important for human balance and movement such as center of mass, center of pressure, ground reaction forces etc. In this study, we discuss a bipedal model for biomechanical sit to stand movement with optimal controller design. The cost optimization for gain scheduling is based upon physiological variables of center of mass, head position, and ground reaction forces. Our simulation results More >

  • Open Access

    ARTICLE

    Adhesive Force of Human Hepatoma HepG2 Cells to Endothelial Cells and Expression of E-Selectin

    Guanbin Song∗,†, Toshiro Ohashi, Naoya Sakamoto, Masaaki Sato

    Molecular & Cellular Biomechanics, Vol.3, No.2, pp. 61-68, 2006, DOI:10.3970/mcb.2006.003.061

    Abstract Expression of adhesion molecules may play an important role in the interaction of tumor cells with vascular endothelial cells during tumor invasion and metastasis. In this study, the adhesive force of human hepatoma HepG2 cells to human umbilical vein endothelial cells (HUVECs) was investigated using a micropipette aspiration technique. Expression of an adhesion molecule, E-selectin, was also observed by immunofluorescence microscopy. In particular, the adhesive force after stimulation of HUVECs with recombinant human interleukin-1β (rhIL-1β) was examined. The results demonstrated that the adhesive force of HepG2 cells to stimulated HUVECs is significantly higher than that More >

  • Open Access

    ARTICLE

    Influence of Layer Height on Thermal Buoyancy Convection in A System with Two Superposed Fluids Confined in A Parallelepipedic Cavity

    Sunil Punjabi1, K. Muralidhar2, P. K. Panigrahi2

    FDMP-Fluid Dynamics & Materials Processing, Vol.2, No.2, pp. 95-106, 2006, DOI:10.3970/fdmp.2006.002.095

    Abstract Convection in a differentially heated two-layer system consisting of air and water was studied experimentally, using laser-interferometry. The cavity used for flow visualization was square in cross-section and rectangular in-plan having dimensions of 447 × 32 × 32 mm3. Experiments performed over different layer thicknesses of water filled in a square cross-section cavity, the rest being air, are reported in the present work. The following temperature differences for each layer height were imposed across the hot and the cold walls of the superposed fluid layers: (i) ΔT=10K and (ii)ΔT =18 K. The present study was aimed… More >

  • Open Access

    REVIEW

    Biophysical approaches for studying the integrity and function of tight junctions

    S.R.K. Vedula1, T.S. Lim2, P.J. Kausalya3, W. Hunziker3, G. Rajagopal2, C.T. Lim1,4

    Molecular & Cellular Biomechanics, Vol.2, No.3, pp. 105-124, 2005, DOI:10.3970/mcb.2005.002.105

    Abstract Cell-cell adhesion is an extremely important phenomenon as it influences several biologically important processes such as inflammation, cell migration, proliferation, differentiation and even cancer metastasis. Furthermore, proteins involved in cell-cell adhesion are also important from the perspective of facilitating better drug delivery across epithelia. The adhesion forces imparted by proteins involved in cell-cell adhesion have been the focus of research for sometime. However, with the advent of nanotechnological techniques such as the atomic force microscopy (AFM), we can now quantitatively probe these adhesion forces not only at the cellular but also molecular level. Here, we More >

  • Open Access

    ARTICLE

    On the Nature and Structure of Possible Three-dimensional Steady Flows in Closed and Open Parallelepipedic and Cubical Containers under Different Heating Conditions and Driving Forces.

    Marcello Lappa1, 2

    FDMP-Fluid Dynamics & Materials Processing, Vol.1, No.1, pp. 1-20, 2005, DOI:10.3970/fdmp.2005.001.001

    Abstract Possible natural transport mechanisms in cubical and shallow cavities with different heating conditions (from below or from the side) are investigated by means of numerical solution of the non-linear model equations and multiprocessor computations. Attention is focused on a variety of three-dimensional steady effects that can arise in such configurations in the case of low-Pr liquids (silicon melt) even for relatively small values of the temperature gradient due to localized boundary effects and/or true instabilities of the flow. Such aspects are still poorly known or completely ignored owing to the fact that most of the More >

  • Open Access

    REVIEW

    Review : Uterine mast cells: A new hypothesis to understand how we are born

    M. ISOLDE RUDOLPH1, I. GINA ROJAS2, ALICIA B. PENISSI3

    BIOCELL, Vol.28, No.1, pp. 1-11, 2004, DOI:10.32604/biocell.2004.28.001

    Abstract Birth is the result of complex, well-defined, and coordinated events, that are tightly regulated by endocrine, nervous, and immune responses, and take place primarily in the female reproductive tract. Various mechanisms and mediators involved in pregnancy, labor, and delivery, are highly conserved among different mammalian species and mast cells emerge as potential and crucial participants in these processes, as it is discussed in this review. More >

  • Open Access

    ARTICLE

    Fast Multipole Boundary Element Analysis of Corrosion Problems

    S.Aoki1, K.Amaya2, M.Urago3, A.Nakayama4

    CMES-Computer Modeling in Engineering & Sciences, Vol.6, No.2, pp. 123-132, 2004, DOI:10.3970/cmes.2004.006.123

    Abstract The Fast Multipole Boundary Element Method(FMBEM) which is suitable for a large scale computation is applied to corrosion analysis. Many techniques of the FMBEM on the potential problems can be usefully employed. Additionally, some procedures are developed for corrosion analysis. To cope with the non-linearity due to the polarization curve, the Bi-CGSTAB iterative method which is commonly used in the FMBEM is modified. To solve infinite domain problems, the M00 which is obtained naturally in the multipole expansion is conveniently used. A pipe element for the FMBEM is developed. A couple of example problems are More >

  • Open Access

    ARTICLE

    Entry Length and Wall Shear Stress in Uniformly Collapsed-Pipe Flow

    M. Thiriet1, S. Naili2, C. Ribreau2

    CMES-Computer Modeling in Engineering & Sciences, Vol.4, No.3&4, pp. 473-488, 2003, DOI:10.3970/cmes.2003.004.473

    Abstract The laminar steady flow of incompressible Newtonian fluid is studied in rigid pipes with cross configuration of a collapsed tube to determine both the entry length and the wall shear stress (WSS). The cross section shapes have been defined from the collapse of an infinitely long elastic tube subjected to an uniform transmural pressure. Five characteristic collapsed configurations, from the unstressed down to the point-contact states, with a finite and infinite curvature radius at the contact point, are investigated, although the wall contact is not necessary observed in veins. Such collapsed shapes induce cross gradient More >

  • Open Access

    ARTICLE

    Three Dimensional Wave Scattering by Rigid Circular Pipelines Submerged in an Acoustic Waveguide

    António Tadeu, Andreia Pereira, Luís Godinho1

    CMES-Computer Modeling in Engineering & Sciences, Vol.2, No.1, pp. 49-62, 2001, DOI:10.3970/cmes.2001.002.049

    Abstract The Boundary Element Method (BEM) is used to compute the three-dimensional variation pressure field generated by a point pressure source inside a flat waveguide channel filled with a homogeneous fluid, in the presence of infinite rigid circular pipelines. The problem is solved in the frequency domain, using boundary elements to model the pipeline and an appropriate Green's function to simulate the free surface and the rigid floor of the channel. Because of the 2 ---1/2 ---D geometry of the problem, the separation of variables has been used, and the solution at each frequency is expressed in… More >

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