Aleš Belšak¹, Jurij Prezelj²

Structural Durability & Health Monitoring, Vol.3, No.4, pp. 239-246, 2007, DOI:10.3970/sdhm.2007.003.239

Abstract Noise source vizualization represents an important tool in the field of technical acoustics. There are many different techniques of noise source visualization. Most of them, however, are intended for a specific noise source in a specific type of acoustic environment. Consequently, a certain visualization method can be used only for certain types of noise sources in a specific acoustic environment and in a restricted frequency area. This paper presents a new visualization method of complex noise sources on the basis of the use of an acoustic camera. A new algorithm has been used, which makes More >

KIVANÇ ERGEN^*, MUHAMMET BEKTAŞ^**, SINA GÖKÇE^**, RÜSTEM NURTEN^**

BIOCELL, Vol.31, No.1, pp. 61-66, 2007, DOI:10.32604/biocell.2007.31.061

Abstract Eukaryotic elongation factor 2 (eEF-2) can undergo ADP-ribosylation in the absence of diphtheria toxin. The binding of free ADP-ribose and endogenous transferase-dependent ADP-ribosylation were distinct reactions for eEF-2, as indicated by different findings. Incubation of eEF-2 tryptic fragment 32/33 kDa (32F) with NAD was ADP-ribosylated and gave rise to the covalent binding of ADP-ribose to eEF-2. 32F was revealed to be at the C-terminal by Edman degradation sequence analysis.
In our study, the elution of 32F from SDS-PAGE was ADP-ribosylated both in the presence and absence of diphtheria toxin. These results suggest that endogenous ADP-ribosylation More >

L. Susmel^1,2, D. Taylor², R. Tovo¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.1, No.2, pp. 81-86, 2007, DOI:10.3970/icces.2007.001.081

Abstract This paper investigates some practical aspects related to the use of the Theory of Critical Distances (TCD) when employed to estimate notch fatigue limits. The accuracy of different formalisations of the theory was checked by using experimental data taken from the literature. This exercise allowed us to confirm that the simplest formalisation of the TCD, in which both critical distance and critical stress are material constants [1], is also the most accurate one, giving predictions falling within an error interval of about ±20%. The TCD is also accurate when applied to notches having large opening More >

T. Tanaka¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.4, No.4, pp. 251-256, 2007, DOI:10.3970/icces.2007.004.251

Abstract The viscoplastic constitutive relations with kinematic strain hardening-softening model for geomaterials are developed. The constitutive models include strain-rate dependent properties based on the thoery by Duvaut-Lions. The dynamic relaxation method for static problems and the dynamic analysis for earthquake responses are applied to boundary value problems using finite element methods. More >

S.Y. Wang^1,2, K.M. Lim^2,3, B.C. Khoo^2,3, M.Y. Wang⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.21, No.1, pp. 1-40, 2007, DOI:10.3970/cmes.2007.021.001

Abstract The level set method is a numerical technique for simulating moving interfaces. In this paper, an unconditionally BIBO (Bounded-Input-Bounded-Output) time-stable consistent meshfree level set method is proposed and applied as a more effective approach to simultaneous shape and topology optimization. In the present level set method, the meshfree infinitely smooth inverse multiquadric Radial Basis Functions (RBFs) are employed to discretize the implicit level set function. A high level of smoothness of the level set function and accuracy of the solution to the Hamilton-Jacobi partial differential equation (PDE) can be achieved. The resulting dynamic system of… More >

Shuji Takashima¹, Michihiko Nakagaki², Noriyuki Miyazaki¹

CMES-Computer Modeling in Engineering & Sciences, Vol.20, No.3, pp. 193-202, 2007, DOI:10.3970/cmes.2007.020.193

Abstract Composite materials have complicated microstructures. These microstructures affect the macroscopic deformation of composite materials. In the present study, we focus on the effect of particle size in a particle-dispersed composite material on the mechanical strength of the material. For this purpose, we derived a macroscopic elastic-plastic constitutive equation using a modified version of the Eshelby's equivalent inclusion method combined with the gradient plasticity. We incorporated this macroscopic elastic-plastic constitutive equation into a finite element program and performed a homogenized finite element analysis of a particle-dispersed composite material in which both the macroscopic and microscopic behaviors More >

Dorota Kierszniewska-Stepień¹, Tadeusz Pietras¹, Pawel Górski¹, Henryk Stepien²

European Cytokine Network, Vol.17, No.1, pp. 75-79, 2006

Abstract Chronic obstructive pulmonary disease (COPD) is a disorder which encompasses not only morphological changes in parenchyma, central and peripheral airways but also in structural and functional changes of pulmonary vessels. The role of angiogenic factors leading to abnormal pulmonary vessel remodeling remains unclear. We have investigated a cytokine vascular endothelial growth factor (VEGF) known to be involved in angiogenesis, and its soluble receptors (sVEGF R1, sVEGF R2) in the serum of 20 patients with mild COPD and 10 patients with very severe COPD, using sensitive enzyme-linked immunoassays. The control group consisted of 10 healthy volunteers.… More >

Angela Garau¹, Riccardo Bertini², Marco Mosca², Cinzia Bizzarri², Roberto Anacardio², Sara Triulzi¹, Marcello Allegretti², Pietro Ghezzi¹, Pia Villa^1,3

European Cytokine Network, Vol.17, No.1, pp. 35-41, 2006

Abstract The chemokine receptors CXCR1 and CXCR2 present on polymorphonuclear neutrophils (PMN), bind the chemokine CXC ligand 8 (CXCL8)/interleukin-8 (IL-8), and have a key role in PMN recruitment in inflammation. Based on the structure of reparixin, a small-molecular-weight allosteric inhibitor of CXCR1, we designed a dual inhibitor of CXCR1 and CXCR2 with a longer in vivo half-life, DF2156A. This molecule inhibited human and rat PMN migration in response to CXCR1 and CXCR2 ligands and showed an elimination half-life following i.v. administration, of 19 hours. In a rat model of cerebral ischemia/reperfusion induced by temporary (90 min) More >

Soraya Meghari¹, Benoît Desnues¹, Christian Capo¹, Georges E. Grau^1,2, Didier Raoult¹, Jean-Louis Mege¹

European Cytokine Network, Vol.17, No.4, pp. 253-259, 2006, DOI:10.1684/ecn.2006.0041

Abstract Q fever is an infectious disease caused by Coxiella burnetii, which may become chronic when cytokine network and cell-mediated immune responses are altered. Chemokines, such as Regulated upon Activation, Normal T cell Expressed and Secreted (RANTES, CCL5) and Monocyte Chemoattractant Protein-1 (MCP-1, CCL2), are specialized in the trafficing of peripheral blood mononuclear cells (PBMC), and are associated with T cell polarization that is essential for intracellular survival of C. burnetii. The present study investigated whether or not the infection status (no infection and acute or chronic infection with C. burnetii) of donors, affected the production of the two… More >

Gabriel P. Haas

Canadian Journal of Urology, Vol.13, No.6, pp. 3307-3307, 2006

Abstract This article has no abstract. More >