N. Liu,¹,W. Gao ¹, C.M. Song¹, N. Zhang²

CMES-Computer Modeling in Engineering & Sciences, Vol.72, No.2, pp. 79-102, 2011, DOI:10.3970/cmes.2011.072.079

Abstract This paper presents the probabilistic dynamic analysis of vehicle-bridge interaction systems. The bridge's and vehicle's parameters are considered as random variables as well as the road surface roughness is modeled as random process. A two-degree-of-freedom spring-mass system is used to represent a moving vehicle and the bridge is modeled as an Euler-Bernoulli beam. From the equation of motion for the vehicle-bridge coupling system, the expressions for mean value and standard deviation of bridge response are developed by using the random variable's functional moment method. The effects of the individual system parameters and the road surface More >

Chun Yang^1,2, Dalin Tang², Satya Atluri³

CMES-Computer Modeling in Engineering & Sciences, Vol.72, No.1, pp. 53-78, 2011, DOI:10.3970/cmes.2011.072.053

Abstract Previously, we introduced a computational procedure based on three-dimensional meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data to quantify patient-specific carotid atherosclerotic plaque growth functions and simulate plaque progression. Structure-only models were used in our previous report. In this paper, fluid-stricture interaction (FSI) was added to improve on prediction accuracy. One participating patient was scanned three times (T1, T2, and T3, at intervals of about 18 months) to obtain plaque progression data. Blood flow was assumed to laminar, Newtonian, viscous and incompressible. The Navier-Stokes equations with arbitrary Lagrangian-Eulerian (ALE) formulation… More >

C. T. Wu¹, F.-L. Yang², D. L. Young³

CMC-Computers, Materials & Continua, Vol.23, No.2, pp. 135-154, 2011, DOI:10.3970/cmc.2011.023.135

Abstract This paper proposes a method that can calculate the hydrodynamic force of a non-circular object in an inviscid, irrotational, and incompressible flow with the presence of external flow singularities. In order to handle irregular object, the method of fundamental solutions (MFS) is employed to numerically construct the singularity system that describes the body and the flow motion and meets the boundary condition. The obtained singularity system is then integrated into the generalized Lagally theorem to compute the instantaneous hydrodynamic force via algebraic calculations and to describe the unsteady interaction of the object and its ambient… More >

J. Sladek¹, V. Sladek¹, P. Stanak¹, Ch. Zhang², M. Wünsche²

CMC-Computers, Materials & Continua, Vol.23, No.1, pp. 35-68, 2011, DOI:10.3970/cmc.2011.023.035

Abstract A contour integral method is developed for the computation of stress intensity, electric and magnetic intensity factors for cracks in continuously nonhomogeneous magnetoelectroelastic solids under a transient dynamic load. It is shown that the asymptotic fields in the crack-tip vicinity in a continuously nonhomogeneos medium are the same as in a homogeneous one. A meshless method based on the local Petrov-Galerkin approach is applied for the computation of the physical fields occurring in the contour integral expressions of intensity factors. A unit step function is used as the test functions in the local weak-form. This More >

Khalil Khanafer^a, Kambiz Vafai^b,*

Frontiers in Heat and Mass Transfer, Vol.1, No.2, pp. 1-9, 2010, DOI:10.5098/hmt.v1.2.3004

Abstract A study was conducted to demonstrate the applications of microcantilevers in biomedical and thermo/fluid fields. The deflection of the microcantilevers due to biomaterial and turbulence effects was highlighted in this work. The novel patented microcantilever assemblies that were presented in this study can increase the signal and decrease the unfavorable deflection due to flow disturbances. This work paves the road for researchers in the area microcantilever based biosensors to design efficient microsensor systems that exhibit minimal errors in the measurements. Fluid-structure interaction was also utilized to investigate some aspects of the fluid flow and heat More >

LUCIANA MAZZEI¹, ISABEL MERCEDES GARCÍA¹, VALERIA CACCIAMANI¹, MARÍA EUGENIA BENARDÓN¹ AND WALTER MANUCHA^{1, 2, 3}

BIOCELL, Vol.34, No.3, pp. 121-132, 2010, DOI:10.32604/biocell.2010.34.121

Abstract Wilms tumor gene 1 (wt-1), a key regulator of mesenchymal-epithelial transformation, is downregulated during congenital obstructive nephropathy, leading to apoptosis. There is a functional interaction between WT-1 and inducible nitric oxide synthase (iNOS). In this regard, we reported that after neonatal unilateral ureteral obstruction, rosuvastatin prevents apoptosis through an increase in nitric oxide bioavailability, which in turn is linked to higher Hsp70 expression. Hence, the goal of this study was to determine whether a nitric oxide/Hsp70 interaction is involved in changes in WT-1 mRNA expression after ureteral obstruction. Neonatal rats submitted to experimental ureteral obstruction were… More >

Kandus¹ M, D Almorza³, R Boggio Ronceros², JC Salerno¹

Phyton-International Journal of Experimental Botany, Vol.79, pp. 39-46, 2010, DOI:10.32604/phyton.2010.79.039

Abstract Our objective was to determine the genotype-environment interaction (GxE) in a hybrid integrated by maize lines either carrying or not balanced lethal systems. Experiments were conducted in three locations over a period of two years considering each yearlocation combination as a different environment. Yield data were analysed using the Additive Main Effects and Multiplicative Interaction (AMMI) model and the Sites Regression Analysis (SREG). Results were represented by biplots. The AMMI analysis was the best model for determining the interaction. More >

Yu.A. Goritskiy¹, D.G. Tigetov¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.14, No.4, pp. 99-102, 2010, DOI:10.3970/icces.2010.014.099

Abstract It is well-known that process of friction depends immensely on the surface roughness. Also, surfaces change while in friction. Roughness change is influenced by many factors such as shape of asperities, physical characteristics of materials, load, sliding velocity, lubricant and others. It was shown experimentally that roughness reaches a steady form (known as ``equilibrium roughness'') while running-in process. It is ``equilibrium roughness'' that determines a stationary friction mode. More >

M. S. Bapat¹, Y. J. Liu^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.58, No.2, pp. 161-184, 2010, DOI:10.3970/cmes.2010.058.161

Abstract A new definition of the interaction list in the fast multipole method (FMM) is introduced in this paper, which can reduce the moment-to-local (M2L) translations by about 30-40% and therefore improve the efficiency for the FMM. In addition, an adaptive tree structure is investigated, which is potentially more efficient than the oct-tree structure for thin and slender domains as in the case of micro-electro-mechanical systems (MEMS). A combination of the modified interaction list (termed L2 modification in the adaptive fast multipole BEM) and the adaptive tree structure in the fast multipole BEM has been implemented… More >

F.E. Mensah^∗,†, R. Sridhar^†, P. Misra^†

Molecular & Cellular Biomechanics, Vol.7, No.4, pp. 203-212, 2010, DOI:10.3970/mcb.2010.007.203

Abstract This work presents an overview of the use of liposomes for targeted delivery of photosensitizers to tumors for Photodynamic Therapy (PDT). It assesses the results of a quantitative model to explain the interaction of short-pulsed lasers (in the nanosecond and picosecond domains) with a liposome-dye complex in terms of a localized photo-induced thermal mechanism. Incorporation of an organic dye (sulforhodamine) within lipid vesicles has been investigated in conjunction with the effect of laser irradiation on the integrity of the liposome-dye complex. The variation of the absorption coefficient as a function of wavelength for dye-encapsulated liposomes More >