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  • Open Access

    ARTICLE

    Variation in care practices across pediatric acute care cardiology units: Results of the Pediatric Acute Care Cardiology Collaborative (PAC3 ) hospital survey

    Amanda Hoerst1, Adnan Bakar2, Steven C. Cassidy3, Martha Clabby4, Erica Del Grippo5, Margaret Graupe1, Ashraf S. Harahsheh6, Anthony M. Hlavacek7, Stephen A. Hart3, Alaina K. Kipps8, Nicolas L. Madsen1, Dora D. O’Neil9, Sonali S. Patel10, Courtney M. Strohacker11, Ronn E. Tanel12

    Congenital Heart Disease, Vol.14, No.3, pp. 419-426, 2019, DOI:10.1111/chd.12739

    Abstract Background: The Pediatric Acute Care Cardiology Collaborative (PAC3) was estab‐ lished in 2014 to improve the quality, value, and experience of hospital‐based cardiac acute care outside of the intensive care unit. An initial PAC3 project was a compre‐ hensive survey to understand unit structure, practices, and resource utilization across the collaborative. This report aims to describe the previously unknown degree of practice variation across member institutions.
    Methods: A 126‐stem question survey was developed with a total of 412 possible response fields across nine domains including demographics, staffing, available re‐ sources and therapies, and standard care practices. Five supplemental questions ad‐… More >

  • Open Access

    ARTICLE

    Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood

    Charlotte A. Houck1,2, Reinder Evertz3, Christophe P. Teuwen1, Jolien W. Roos‐Hesselink1, Janneke A. E. Kammeraad4, Anthonie L. Duijnhouwer3, Natasja M. S. de Groot3, Ad J. J. C. Bogers2

    Congenital Heart Disease, Vol.14, No.2, pp. 280-287, 2019, DOI:10.1111/chd.12724

    Abstract Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD.
    Study design: In this retrospective multicenter study, 74 patients (68% female) with a cAVSD repaired in childhood were included. Patients’ medical files were evaluated for occurrence of SND, atrioventricular conduction block (AVB), atrial and ventricular tachyarrhythmias.
    Results: Median age at repair was… More >

  • Open Access

    ARTICLE

    Use of 3D models of congenital heart disease as an education tool for cardiac nurses

    Giovanni Biglino1,2, Claudio Capelli2,3, Despina Koniordou3, Di Robertshaw2, Lindsay-Kay Leaver2, Silvia Schievano2,3, Andrew M. Taylor2,3, Jo Wray2

    Congenital Heart Disease, Vol.12, No.1, pp. 113-118, 2017

    Abstract Background: Nurse education and training are key to providing congenital heart disease (CHD) patients with consistent high standards of care as well as enabling career progression. One approach for improving educational experience is the use of 3D patient-specific models.
    Objectives: To gather pilot data to assess the feasibility of using 3D models of CHD during a training course for cardiac nurses; to evaluate the potential of 3D models in this context, from the nurses’ perspective; and to identify possible improvements to optimise their use for teaching.
    Design: A cross-sectional survey.
    Setting: A national training week for cardiac nurses.
    Participants: One… More >

  • Open Access

    ARTICLE

    Comparative Evaluation of Flow Quantification across the Atrioventricular Valve in Patients with Functional Univentricular Heart after Fontan’s Surgery and Healthy Controls: Measurement by 4D Flow Magnetic Resonance Imaging and Streamline Visualization

    Hoi Lam She*, Arno A.W. Roest, Emmeline E. Calkoen, Pieter J. van den Boogaard, Rob J. van der Geest, Mark G. Hazekamp§, Albert de Roos, Jos J.M. Westenberg

    Congenital Heart Disease, Vol.12, No.1, pp. 40-48, 2017

    Abstract Purpose. To evaluate the inflow pattern and flow quantification in patients with functional univentricular heart after Fontan’s operation using 4D flow magnetic resonance imaging (MRI) with streamline visualization when compared with the conventional 2D flow approach.
    Method. Seven patients with functional univentricular heart after Fontan’s operation and twenty-three healthy controls underwent 4D flow MRI. In two orthogonal two-chamber planes, streamline visualization was applied, and inflow angles with peak inflow velocity (PIV) were measured. Transatrioventricular flow quantification was assessed using conventional 2D multiplanar reformation (MPR) and 4D MPR tracking the annulus and perpendicular to the streamline inflow at PIV, and they… More >

  • Open Access

    ABSTRACT

    On the Image-Based Non-Invasive Diagnosis of Cardiovascular Diseases

    Peng Wu1,*, Qi Gao2, Runjie Wei3, Hongping Wang3, Lizhong Wang3

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 27-28, 2019, DOI:10.32604/mcb.2019.05711

    Abstract Cardiovascular diseases are the leading cause of human deaths worldwide. Traditional diagnostic tools of cardiovascular diseases are either based on 2D static medical images, or invasive, bringing troubles to both patients and doctors. Our team is committed to the development of image-based non-invasive diagnostic system for cardiovascular diseases. We have made progress mainly in the following areas: 1) 4D flow technology for heart and large blood vessels. According to MRI 4D Flow data, three-dimensional velocity fields within blood vessels were constructed. Divergence-fee smoothing (DFS) was proposed to eliminate the high frequency noise in the hemodynamic flow field, and make the… More >

  • Open Access

    ABSTRACT

    Multi-Modality Image-Based Modeling Approach for Cardiovascular Disease: Simulation, Assessment, Prediction, and Virtual Surgery

    Dalin Tang1,2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 11-11, 2019, DOI:10.32604/mcb.2019.05170

    Abstract Medical imaging and image-based modeling have made considerable progress in recent years in cardiovascular research, such as identifying atherosclerotic plaque morphological and mechanical risk factors which may be used in developing improved patient screening strategies, and performing virtual heart surgery seeking optimal surgical procedures for best post-surgical outcome. We will report recent progress in using multi-modality image-based models to predict vulnerable plaque progression and vulnerability change. In particular, we will report our recent results using IVUS+OCT data to obtain more accurate stress/strain calculations. Inflammation and cap erosion will affect cap material properties. If OCT image could provide inflammation and erosion… More >

  • Open Access

    ABSTRACT

    Preface: The First International Symposium on Biomechanics and Mechanobiology in Cardiovascular System

    Zhiyong Li1,2,*, Dalin Tang1,3

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 1-7, 2019, DOI:10.32604/mcb.2019.05830

    Abstract Cardiovascular disease remains as the leading cause of death worldwide, and the technologies developed by different groups need to be communicated and shared with all related research communities for a boarder implementation. Challenges in imaging technology, mathematical modelling, material description, mechanical representation, disease progression, prediction methods, and final transition to clinical applications are calling for collaborative effort of the entire research community to act together and bring research effort closer to actual clinical applications. Researchers from different disciplines need to reach out to share their expertise, as well as to listen to other people to understand the big picture, understand… More >

  • Open Access

    EDITORIAL

    Preface: Innovations and Current Trends in Computational Cardiovascular Modeling and Beyond: Molecular, Cellular, Tissue and Organ Biomechanics with Clinical Applications

    Dalin Tang1,2,*, Zhiyong Li1

    CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.2, pp. 109-113, 2018, DOI:10.31614/cmes.2018.04201

    Abstract This article has no abstract. More >

  • Open Access

    ABSTRACT

    Intravascular Ultrasound (IVUS)-Based Computational Modeling and Planar Biaxial Artery Material Properties for Human Coronary Plaque Vulnerability Assessment

    Mingchao Cai, Chun Yang, Mehmet H. Kural, Richard Bach, David Muccigrosso, Deshan Yang, Jie Zheng, Kristen L. Billiar, Dalin Tang

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.19, No.4, pp. 97-104, 2011, DOI:10.3970/icces.2011.019.097

    Abstract Image-based computational modeling has been introduced for vulnerable atherosclerotic plaques to identify critical mechanical conditions which may be used for better risk assessment and rupture predictions. In vivo patient-specific coronary plaque models are lagging due to limitations on non-invasive image resolution, flow data, and vessel material properties. We propose a procedure where intravascular ultrasound (IVUS) imaging, biaxial mechanical testing and computational modeling are combined together to acquire better and more complete plaque data and make more accurate plaque vulnerability assessment and predictions. More >

  • Open Access

    ABSTRACT

    Image-Based Computational Modeling for Cardiovascular Diseases with Potential Clinical Applications

    Dalin Tang1, Chun Yang2, Pedro N. del Nido3, Tal Geva3, Chun Yuan4, Tom Hatsukami5, Fei Liu4, Jie Zheng6, Pamela K. Woodard6

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.1, No.1, pp. 1-6, 2007, DOI:10.3970/icces.2007.001.001

    Abstract Image-based computational models for blood flow in the heart and diseased arteries have been developed for disease assessment and potential clinical applications. Models with fluid-structure interactions for human right ventricle (RV) remodeling surgery design, carotid and coronary atherosclerotic plaques and abdominal aortic aneurysm (AAA) were presented. Organ morphology, material properties, governing equations, proper initial and boundary conditions, controlling factors and research focuses for each model were discussed. More >

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