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  • Open Access

    REVIEW

    An integrated analysis of mRNA-miRNA transcriptome data revealed hub regulatory networks in three genitourinary cancers

    Mian LIU1, Xumeng ZHANG2, *

    BIOCELL, Vol.41, No.1, pp. 19-26, 2017, DOI:10.32604/biocell.2017.41.019

    Abstract Bladder, kidney, prostate and testicular carcinoma are the top four genitourinary cancers in China. Here we analyzed mRNA and miRNA expression profiles of carcinomas of the bladder (TCC), kidney (ccRCC) and testis (TGCT) to uncover their specific regulatory mechanisms. The gene expression profiles of GSE31617 were downloaded from GEO database, which contained 27 samples, including 10 TCC, 7 TGCT and 10 ccRCC. Specific up- and downregulated differentially expressed genes (DEGs) and differentially expressed microRNAs (DEmiRNAs) of each cancer were selected and target genes of DEmiRNAs were predicted. Gene interaction network of the shared genes and… More >

  • Open Access

    ARTICLE

    A Controlled Conditions of Dynamic Cold Storage Using Nano fluid as PCM

    Bin Liu1, Zhaodan Yang1, Yahui Wang1, Rachid Bennacer1,2

    FDMP-Fluid Dynamics & Materials Processing, Vol.13, No.1, pp. 37-47, 2017, DOI:10.3970/fdmp.2017.013.037

    Abstract The dynamic thermal history of storage product system is related to the insulation and also to the inertia. Use a new porous media doped with nanofluid PCM to improve the system efficiency. The analysis of the porous sponge thickness with 8 mm, 16 mm and 20 mm, the integrated nanofluids with 0.1%, 0.15% and 0.2%, the mass of the PCM and the initial temperature of the stored product with -1°C, 4°C, 12°C is achieved in order to underline the advantages of the new saturated porous media (sponges) with the phase change material (PCM) /Al2O3-H2O nanofluid. The… More >

  • Open Access

    ARTICLE

    Mixed Convection of a Nanofluid in a Vertical Anisotropic Porous Channel with Heated/Cooled Walls

    S. Slama1, H. Kahalerras1, B. Fersadou1

    FDMP-Fluid Dynamics & Materials Processing, Vol.13, No.3, pp. 155-172, 2017, DOI:10.3970/fdmp.2017.013.155

    Abstract A numerical study is conducted to investigate the problem of mixed convection of a nanofluid in a vertical porous channel with one wall heated and the other cooled. The Darcy-Brinkman-Forchheimer model is used to describe the flow in the porous medium, considered as anisotropic in thermal conductivity, and the two-phase approach is adopted to simulate the motion of the nanofluid. The governing equations with the associated boundary conditions are solved by the finite volume method. The parametric study is focused on the variation of the Richardson number Ri, the heat fluxes ratio Rq, the Darcy number… More >

  • Open Access

    ARTICLE

    Lattice Boltzmann Method for Simulation of Nanoparticle Brownian Motion and Magnetic Field Effects on Free Convection in A Nanofluid-filled Open Cavity with Heat Generation/Absorption and Non Uniform Heating on the Left Solid Vertical Wall

    Mohamed Ammar Abbassi1, Bouchmel Mliki1, Ridha Djebali1,2

    FDMP-Fluid Dynamics & Materials Processing, Vol.13, No.2, pp. 59-83, 2017, DOI:10.3970/fdmp.2017.013.059

    Abstract This article reports a numerical study of nanoparticle Brownian motion and magnetic field effects by natural convection in a nanofluid-filled open cavity with non uniform boundary condition. Lattice Boltzmann Method (LBM) is used to simulate nanofluid flow and heat transfer. The effective thermal conductivity and viscosity of nanofluid are calculated by KKL (Koo-Kleinstreuer-Li) correlation. In this model effect of Brownian motion on the effective thermal conductivity and effective viscosity is considered and examined. Simulations have been carried out for the pertinent parameters in the following ranges: Rayleigh number (Ra=103−106), Hartmann number (Ha=0-60), nanoparticle volume concentration (Φ=0–0.04) and More >

  • Open Access

    ARTICLE

    Investigation of the Melting Coupled Natural Convection of Nano Phase Change Material: A Fan Less Cooling of Heat Sources

    Mustapha FARAJI1

    FDMP-Fluid Dynamics & Materials Processing, Vol.13, No.1, pp. 19-36, 2017, DOI:10.3970/fdmp.2017.013.019

    Abstract A two-dimensional numerical model that accounts for heat transfer by conduction and natural convection in the molten region of nano enhanced Phase Change Material (PCM) is performed. Numerical investigations were conducted using an enthalpy- porosity method in order to examine the impact of the dispersion of copper (CuO) nanoparticles on the heat source temperature and the effect on the heat sink secured working time and the melting rate. Results show that heat spreads more easily along the conducting plate and to the PCM and, consequently, the PCM melts rapidly and the heat source is efficiency More >

  • Open Access

    ARTICLE

    Cycle Time Reduction in Injection Molding by Using Milled Groove Conformal Cooling

    Mahesh S. Shinde1,*, Kishor M. Ashtankar2

    CMC-Computers, Materials & Continua, Vol.53, No.3, pp. 207-217, 2017, DOI:10.32604/cmc.2017.053.223

    Abstract This paper presents simulation study on Milled Grooved conformal cooling channels (MGCCC) in injection molding. MGCCC has a more effective cooling surface area which helps to provide efficient cooling as compared to conventional cooling. A case study of Encloser part is investigated for cycle time reduction and quality improvement. The performance designs of straight drilled are compared with MGCCC by using Autodesk Moldflow Insight (AMI) 2016. The results show total 32.1% reduction of cooling time and 9.86% reduction of warpage in case of MGCCC as compared to conventional cooling. More >

  • Open Access

    ARTICLE

    A Randomized Controlled Open-Label Pilot Study of Simvastatin Addition to Whole-Brain Radiation Therapy in Patients With Brain Metastases

    Manal El-Hamamsy*, Hesham Elwakil, Amr S. Saad, May A. Shawki*

    Oncology Research, Vol.24, No.6, pp. 521-528, 2016, DOI:10.3727/096504016X14719078133528

    Abstract Statins have been reported to have a potential radiosensitizing effect that has not been evaluated in clinical trials. The aim of this study was to evaluate the efficacy and safety of simvastatin in addition to whole-brain radiation therapy (WBRT) in patients with brain metastases (BM). A prospective randomized, controlled, open-label pilot study was conducted on 50 Egyptian patients with BM who were randomly assigned to receive 30-Gy WBRT (control group: 25 patients) or 30 Gy WBRT+ simvastatin 80 mg/day for the WBRT period (simvastatin group: 25 patients). The primary outcome was radiological response at 4… More >

  • Open Access

    ARTICLE

    Genetic diversity of guava (Psidium guajava L.) from Central Mexico revealed by morphological and RAPD markers

    Valera-Montero LL, PJ Muñoz-Rodríguez, H Silos-Espino, S Flores-Benítez

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 176-183, 2016, DOI:10.32604/phyton.2016.85.176

    Abstract Guava fruit produced in Calvillo, Aguascalientes (Mexico) is considered to be of the best quality in this country. Nevertheless, growers from this place empirically know that there is a noticeable variation among individual trees within the same orchard, and variation among individuals from different orchards. In order to have a clear evidence of this, morphology analysis of guava was performed taking data from seventy nine individuals out of thirty six orchards, while RAPD was performed on a subset of twenty six individuals. Similarity was found for morphology data ranging from 87-100%, while similarity from RAPD More >

  • Open Access

    REVIEW

    Nanocellulose-Enabled Electronics, Energy Harvesting Devices, Smart Materials and Sensors: A Review

    Ronald Sabo1*, Aleksey Yermakov2, Chiu Tai Law3, Rani Elhajjar4

    Journal of Renewable Materials, Vol.4, No.5, pp. 297-312, 2016, DOI:10.7569/JRM.2016.634114

    Abstract Cellulose nanomaterials have a number of interesting and unique properties that make them well-suited for use in electronics applications such as energy harvesting devices, actuators and sensors. Cellulose nanofibrils and nanocrystals have good mechanical properties, high transparency, and low coefficient of thermal expansion, among other properties that facilitate both active and inactive roles in electronics and related devices. For example, these nanomaterials have been demonstrated to operate as substrates for flexible electronics and displays, to improve the efficiency of photovoltaics, to work as a component of magnetostrictive composites and to act as a suitable lithium More >

  • Open Access

    ARTICLE

    A Finite Element Procedure for Analysis of Chemo-Mechanical Coupling Behavior of Hydrogels

    Wei Wei1,2, Qingsheng Yang1,3

    CMES-Computer Modeling in Engineering & Sciences, Vol.112, No.1, pp. 33-58, 2016, DOI:10.3970/cmes.2016.112.033

    Abstract Chemo-mechanical coupling behavior of materials is a transformation process between mechanical and chemical energy. In this paper, based on the coupled chemo-mechanical constitutive equations and governing equations during isothermal process, the equivalent integral forms of chemo-mechanical coupling governing equations and corresponding finite element procedure are obtained by using Hamilton's principle. An isoparametric plane element for chemo-mechanical coupling is associated into ABAQUS finite element package through user element subroutine UEL. The numerical examples exhibit that the ionic concentration variation can cause mechanical deformation and mechanical action can produce redistribution of ionic concentration for hydrogels. It is More >

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