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  • Open Access

    ARTICLE

    Utilization of inhaled nitric oxide after surgical repair of truncus arteriosus: A multicenter analysis

    Christine M. Riley1, Christopher W. Mastropietro2, Peter Sassalos3, Jason R. Buckley4, John M. Costello4, Ilias Iliopoulos5, Aimee Jennings6, Katherine Cashen7, Sukumar Suguna Narasimhulu8, Keshava M. N. Gowda9, Arthur J. Smerling10, Michael Wilhelm11, Aditya Badheka12, Adnan Bakar13,14, Elizabeth A. S. Moser15, Venu Amula16

    Congenital Heart Disease, Vol.14, No.6, pp. 1078-1086, 2019, DOI:10.1111/chd.12849

    Abstract Background: Elevated pulmonary vascular resistance (PVR) is common following repair of truncus arteriosus. Inhaled nitric oxide (iNO) is an effective yet costly therapy that is frequently implemented postoperatively to manage elevated PVR.
    Objectives: We aimed to describe practice patterns of iNO use in a multicenter cohort of patients who underwent repair of truncus arteriosus, a lesion in which recovery is often complicated by elevated PVR. We also sought to identify patient and center factors that were more commonly associated with the use of iNO in the postoperative period.
    Design: Retrospective cohort study.
    Setting: 15 tertiary care pediatric referral centers.
    Patients:More >

  • Open Access

    ARTICLE

    Coupled Digital Image Correlation and Peridynamics for Full-Field Deformation Measurement and Local Damage Prediction

    Tianyi Li1, Xin Gu1, Qing Zhang1,*, Dong Lei1

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.2, pp. 425-444, 2019, DOI:10.32604/cmes.2019.06700

    Abstract Digital image correlation (DIC) measurement technique and peridynamics (PD) method have been applied in specific fields extensively owing to their respective advantages in obtaining full-field deformation and local failure of loaded materials and structures. This study provides a simple way to couple DIC measurements with PD simulations, which can circumvent the difficulties of DIC in dealing with discontinuous deformations. Taking the failure analysis of a compact tension specimen of aluminum alloy and a static three-point bending concrete beam as examples, the DIC experimental system firstly measures the full-field displacements, and then the PD simulation is More >

  • Open Access

    ARTICLE

    Genetic-Frog-Leaping Algorithm for Text Document Clustering

    Lubna Alhenak1, Manar Hosny1,*

    CMC-Computers, Materials & Continua, Vol.61, No.3, pp. 1045-1074, 2019, DOI:10.32604/cmc.2019.08355

    Abstract In recent years, the volume of information in digital form has increased tremendously owing to the increased popularity of the World Wide Web. As a result, the use of techniques for extracting useful information from large collections of data, and particularly documents, has become more necessary and challenging. Text clustering is such a technique; it consists in dividing a set of text documents into clusters (groups), so that documents within the same cluster are closely related, whereas documents in different clusters are as different as possible. Clustering depends on measuring the content (i.e., words) of… More >

  • Open Access

    ABSTRACT

    Mechano-Electric Feedback and Arrhythmogenic Current Generation in A Computational Model of Coupled Myocytes

    Viviane Timmermann1, Kevin Vincent2, Joakim Sundnes1, Andrew D. McCulloch2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 133-133, 2019, DOI:10.32604/mcb.2019.07311

    Abstract Heterogeneous mechanical dyskinesis has been implicated in arrhythmogenic phenotypes. Strain-induced perturbations to cardiomyocyte electrophysiology (EP) may trigger arrhythmias via a variety of mechano-electric feedback (MEF) mechanisms. While the role of stretch-activated ionic currents (SACs) has been investigated intensively using computational models, experimental studies have shown that mechanical strain can also trigger intra- and inter-cellular calcium waves. To investigate whether the inherent strain dependence of myofilament calcium affinity may promote arrhythmogenic intra- and inter-cellular calcium waves under conditions of pathologic mechanical heterogeneity, we coupled a mathematical model of excitation-contraction coupling (ECC) in rabbit ventricular myocytes to… More >

  • Open Access

    ABSTRACT

    Fully-Coupled Fluid-Structure Interaction (FSI) Simulations of Heart Valve-Left Ventricle Dynamics

    Wei Sun1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 64-64, 2019, DOI:10.32604/mcb.2019.08533

    Abstract Fluid–structure interaction (FSI) is a common phenomenon in biological systems. FSI problems of practical interest, such as fish/mammalian swimming, insect/bird flight, and human cardiac blood flow and respiration often involve multiple 3D immersed bodies with complex geometries undergoing very large structural displacements, and inducing very complex flow phenomena. Simulation of heart valve FSI is a technically challenging problem due to the large deformation of the valve leaflets through the cardiac fluid domain in the atrium and ventricular chambers.
    Recently, we developed a FSI computational framework [1] for modeling patient-specific left heart (LH) dynamics using smoothed… More >

  • Open Access

    ARTICLE

    Partitioned Method of Insect Flapping Flight for Maneuvering Analysis

    Minato Onishi1, Daisuke Ishihara1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.1, pp. 145-175, 2019, DOI:10.32604/cmes.2019.06781

    Abstract This study proposed a partitioned method to analyze maneuvering of insects during flapping flight. This method decomposed the insect flapping flight into wing and body subsystems and then coupled them via boundary conditions imposed on the wing’s base using one-way coupling. In the wing subsystem, the strong coupling of the flexible wings and surrounding fluid was accurately analyzed using the finite element method to obtain the thrust forces acting on the insect’s body. The resulting thrust forces were passed from the wing subsystem to the body subsystem, and then rigid body motion was analyzed in… More >

  • Open Access

    ARTICLE

    Efficient Solution of 3D Solids with Large Numbers of Fluid-Filled Pores Using Eigenstrain BIEs with Iteration Procedure

    Donghong He1, Hang Ma2, *

    CMES-Computer Modeling in Engineering & Sciences, Vol.118, No.1, pp. 15-40, 2019, DOI:10.31614/cmes.2019.04327

    Abstract To deal with the problems encountered in the large scale numerical simulation of three dimensional (3D) elastic solids with fluid-filled pores, a novel computational model with the corresponding iterative solution procedure is developed, by introducing Eshelby’s idea of eigenstrain and equivalent inclusion into the boundary integral equations (BIE). Moreover, by partitioning all the fluid-filled pores in the computing domain into the near- and the far-field groups according to the distances to the current pore and constructing the local Eshelby matrix over the near-field group, the convergence of iterative procedure is guaranteed so that the problem… More >

  • Open Access

    ARTICLE

    Study on Thermal Insulation Performance of Cross-Laminated Bamboo Wall

    Qingfang Lv1,*, Weiyang Wang1, Ye Liu1

    Journal of Renewable Materials, Vol.7, No.11, pp. 1231-1250, 2019, DOI:10.32604/jrm.2019.08345

    Abstract In recent years, bamboo, as a green building material, has attracted more and more attention worldwide. Inspired by the investigation of cross-laminated timber in structural systems, a new engineered cross-laminated bamboo (CLB) consisting of the cross lamination of bamboo scrimber plates is proposed in this paper. To evaluate its potential in structural applications, the thermal insulation performances of the CLB walls and CLB walls with the EPS foam plate were studied and evaluated by the temperature-controlled box-heat flow meter method. Test results indicated that the thermal insulation performance improved with the increase of thickness, but More >

  • Open Access

    ARTICLE

    Systematically Monitoring, Relational Database and Technology Roadmapping for Trends and Innovation Opportunities in Biopolymers

    Selma B. Jaconis1,*, Augusto T. Morita2, Paulo L. A. Coutinho3, Suzana Borschiver1

    Journal of Renewable Materials, Vol.7, No.11, pp. 1221-1230, 2019, DOI:10.32604/jrm.2019.00025 - 14 July 2021

    Abstract In recent years environmental and sustainability concerns have impacted the global chemical industry and instituted a rush to produce products from renewable raw materials. This dynamic, complex and turbulent organizational scenario, around themes touching on the issue of sustainable development model, was created involving a large number of different actors: chemical/petrochemical industries, agroindustry companies, oil/gas companies, brand owners and end users, biotechnology startups, governments, universities and society. This paper proposed the application of a structured and dynamic method of technological prediction for biopolymers in three levels: systematic monitoring process, relational database and the “alive” Technology More >

  • Open Access

    ARTICLE

    Characterization of Manmade and Recycled Cellulosic Fibers for Their Application in Building Materials

    Nadezda Stevulova1,*, Viola Hospodarova1, Adriana Estokova1, Eva Singovszka1, Marian Holub1, Stefan Demcak1, Jaroslav Briancin2, Anton Geffert3, Frantisek Kacik3, Vojtech Vaclavik4, Tomas Dvorsky4

    Journal of Renewable Materials, Vol.7, No.11, pp. 1121-1145, 2019, DOI:10.32604/jrm.2019.07556

    Abstract The aim of this study was to characterize two types of cellulosic fibers obtained from bleached wood pulp and unbleached recycled waste paper with different cellulose content (from 47.4 percent up to 82 percent), to compare and to analyze the potential use of the recycled fibers for building application, such as plastering mortar. Changes in the chemical composition, cellulose crystallinity and degree of polymerization of the fibers were found. The recycled fibers of lower quality showed heterogeneity in the fiber sizes (width and length), and they had greater surface roughness in comparison to high purity… More >

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