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  • Open Access

    ABSTRACT

    Neovascularization and Intraplaque Hemorrhage in Atherosclerotic Plaque Destabilization-A Mathematical Model

    Muyi Guo1, Yan Cai1, Zhiyong Li1,2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 49-49, 2019, DOI:10.32604/mcb.2019.05727

    Abstract Observational studies have identified angiogenesis from the adventitial vasa vasorum and intraplaque hemorrhage (IPH) as critical factors in atherosclerotic plaque progression and destabilization. Here we propose a mathematical model incorporating intraplaque neovascularization and hemodynamic calculation for the quantitative evaluation of atherosclerotic plaque hemorrhage. An angiogenic microvasculature based on histology of a patient’s carotid plaque is generated by two-dimensional nine-point model of endothelial cell migration. Three key cells (endothelial cells, smooth muscle cells and macrophages) and three key chemicals (vascular endothelial growth factors, extracellular matrix and matrix metalloproteinase) are involved in the intraplaque angiogenesis model, and… More >

  • Open Access

    ARTICLE

    Histopathological patterns of ovarian lesions: A study of 161 cases

    Abdulkareem Younis SULEIMAN1, Intisar Salim PITY2, Mohammed R MOHAMMED2, Bashar Abduljabar HASSAWI2

    BIOCELL, Vol.43, No.3, pp. 175-181, 2019, DOI:10.32604/biocell.2019.06884

    Abstract Ovarian lesions are commonly encountered pathologies that cannot be categorized clinicoradiologically. Definite diagnosis is of great importance for therapeutic and prognostic purposes. Histopathology gives accurate diagnosis in most cases. Few cases need supportive tests like immunohistochemistry. Objective: to study the histomorphological diversity of ovarian lesions, their age and location in North of Iraq (Mosul and Duhok). Patients and methods: In the period extended from January 2008 to December 2011, 161 cases of ovarian lesions were collected from pathology departments in Azadi General Hospital “Duhok” and Al-Jamhori Teaching Hospital “Mosul”. Automated tissue processor was used More >

  • Open Access

    ARTICLE

    Deterioration of Antioxidant Competence in Barley Lesion Mimic Mutant 194

    Qunqun Hao1,#, Bo Lyu2,#, Yuhan Tang1,#, Deya Wang1, Yuanyuan Li1, Qingliang Li1, Yuhai Wang1,* and Wenqiang Wang1,*

    Phyton-International Journal of Experimental Botany, Vol.88, No.2, pp. 109-117, 2019, DOI:10.32604/phyton.2019.06734 - 10 May 2024

    Abstract A barley mutant, 194, was observed to exhibit a leaf spot phenotype over the whole course of its growing period. In this study, the phenotype and antioxidant competence were studied in the lesion mimic mutant 194. Plant height was slightly higher in mutant 194 than in the wild type (WT). In addition, leaf spot per plant in mutant 194 was significantly higher than in WT. Antioxidant competence, as indicated by reactive oxygen species (ROS) accumulation, antioxidant enzyme activity, and the expression of antioxidant enzyme-encoding genes was also assessed in mutant 194. Compared to the WT, More >

  • Open Access

    ARTICLE

    A Novel Reversible Data Hiding Scheme Based on Lesion Extraction and with Contrast Enhancement for Medical Images

    Xingxing Xiao1, Yang1,*, Rui Li2, Weiming Zhang3

    CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 101-115, 2019, DOI:10.32604/cmc.2019.05293

    Abstract The medical industry develops rapidly as science and technology advance. People benefit from medical resource sharing, but suffer from privacy leaks at the same time. In order to protect patients’ privacy and improve quality of medical images, a novel reversible data hiding (RDH) scheme based on lesion extraction and with contrast enhancement is proposed. Furthermore, the proposed scheme can enhance the contrast of medial image's lesion area directly and embed high-capacity privacy data reversibly. Different from previous segmentation methods, this scheme first adopts distance regularized level set evolution (DRLSE) to extract lesion and targets at… More >

  • Open Access

    RESIDENT’S CORNER

    The disappearing PI-RADS 5 prostate lesion

    Vikram K. Sabarwal1,2, Cayde Ritchie3, Kareem Rayn4, Baris Turkbey5, Peter Pinto2

    Canadian Journal of Urology, Vol.25, No.2, pp. 9281-9283, 2018

    Abstract Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) identifies prostate cancer on the basis of multiparametric MRI (mpMRI). As an assessment tool, it correctly predicts clinically significant cancer in the vast majority of cases. In this light, we report a rare patient, for whom a PI-RADS 5 lesion vanished over the course of 13 months. More >

  • Open Access

    RESIDENT’S CORNER

    Benign fibrous pseudotumor resulting in orchiectomy despite intraoperative frozen section

    Tomy Y. Perez1, Brian J. O’Hara2, Irvin H. Hirsch1

    Canadian Journal of Urology, Vol.24, No.6, pp. 9132-9136, 2017

    Abstract Fibrous pseudotumors are rare benign lesions that originate within the paratesticular tissues. Local excision is the preferred method of treatment of these tumors over radical orchiectomy, however a definitive diagnosis must be made beforehand given the similarity of these tumors to malignant entities. We present a case of fibrous pseudotumor of the tunica vaginalis and cauda epididymis. A diagnosis of fibrous pseudotumor could not be established despite the use of intraoperative frozen section, therefore necessitating radical orchiectomy. More >

  • Open Access

    ARTICLE

    Coronary artery bypass grafting in infants, children, and young adults for acquired and congenital lesions

    Constantine Mavroudis

    Congenital Heart Disease, Vol.12, No.5, pp. 644-646, 2017, DOI:10.1111/chd.12491

    Abstract Coronary artery disease ranges from congenital in origin such as anomalous aortic origin of a coronary artery (AAOCA) to acquired diseases such as Kawasaki disease, and previously repaired conditions such as transposition of the great arteries. It is not uncommon, in the long run, for proximal coronary stenosis to develop following arterial switch, AAOCA repair, Ross procedure and Kawasaki disease leading to coronary artery bypass grafing (CABG). The objective of this report is to discuss the indications, challenges, and outcomes of CABG in infants, children, and young adults with acquired and congenital lesions. More >

  • Open Access

    RESIDENT’S CORNER

    Management of extramammary Paget’s disease with a staged, modified Mohs technique

    Anant Shukla1, Matthew Stringer2, Pansy Uberoi2, Steven Hudak2, George Kallingal2

    Canadian Journal of Urology, Vol.23, No.4, pp. 8382-8384, 2016

    Abstract Extramammary Paget’s disease (EMPD) is a rare intraepithelial adenocarcinoma arising from apocrine glands. We describe an innovative surgical technique to manage extensive cutaneous malignancies in a notoriously challenging location. The patient is a 78-year-old male who presented with “jock itch” on his left groin refractory to topical treatment. A shave biopsy of the lesion demonstrated non-invasive EMPD which yielded a urology consult. Rather than the standard wide local excision (WLE), which can lead to positive margins, progression, and recurrence, we used a modified the Mohs technique and staged the procedure, providing excellent oncologic and cosmetic More >

  • Open Access

    ARTICLE

    Magnetic resonance imaging for intratesticular and extratesticular scrotal lesions

    Jeffrey M. Woldrich, Ronald D. Im, Fiona M. Hughes-Cassidy, Lejla Aganovic, Kyoko Sakamoto

    Canadian Journal of Urology, Vol.20, No.4, pp. 6855-6859, 2013

    Abstract Introduction: To evaluate magnetic resonance imaging (MRI) utility in intratesticular and extratesticular scrotal diseases.
    Materials and methods: Two radiologists retrospectively reviewed images of patients who underwent ultrasound followed by MRI, categorizing them as intratesticular or extratesticular and malignant, benign, indeterminate, or inadequate study. For patients who underwent surgical excision, pathologic results were also correlated to the presurgical ultrasound and MRI diagnoses.
    Results: Of 69 cases, 38 were intratesticular lesions and 31 were extratesticular lesions. MRI and ultrasound diagnoses were discordant in 21 (55.32%) intratesticular and 19 (61.3%) extratesticular lesions. MRI diagnosis was malignant after an indeterminate ultrasound in… More >

  • Open Access

    RESIDENT’S CORNER

    Adrenal lymphangioma: a rare cystic lesion of the adrenal

    Michael W. Sourial1, Nicole van Rossum2, Robert Sabbagh1

    Canadian Journal of Urology, Vol.20, No.5, pp. 6968-6970, 2013

    Abstract We herein report the case of a left adrenal lymphangioma in a 52-year-old asymptomatic female and review the pertinent literature relatable to this rare, benign lesion. More >

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