Pengcheng Nie^1,2, Xikai Jiang¹, Xu Zheng¹, Dongshi Guan^1,2,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.1, pp. 1-2, 2023, DOI:10.32604/icces.2023.09838

Abstract “How can we measure interface phenomena on the microscopic level” is a fundamental question that has been with us for many years and is also listed in recent Science 125 question. It is even harder to explore the electrified interface. In this work, we report atomic-force-microscope measurements of interfacial dynamics of an electrified room-temperature ionic liquid (RTIL)-solid interface. RTILs are intriguing fluids that have drawn much attention in applications ranging from tribology and catalysis to energy storage. With strong electrostatic interaction between ions, their interfacial behaviors can be modulated by controlling energetics of the electrified… More >

EFFAT ALEMZADEH¹, LEILA ALLAHQOLI², HAMIDEH DEHGHAN³, AFROOZ MAZIDIMORADI⁴, ALIREZA GHASEMPOUR³, HAMID SALEHINIYA^5,*

Oncology Research, Vol.31, No.5, pp. 667-675, 2023, DOI:10.32604/or.2023.028406 - 21 July 2023

Abstract Liquid biopsy, including both circulating tumor cells and circulating tumor DNA, is becoming more popular as a diagnostic tool in the clinical management of breast cancer. Elevated concentrations of these biomarkers during cancer treatment may be used as markers for cancer progression as well as to understand the mechanisms underlying metastasis and treatment resistance. Thus, these circulating markers serve as tools for cancer assessing and monitoring through a simple, non-invasive blood draw. However, despite several study results currently noting a potential clinical impact of ctDNA mutation tracking, the method is not used clinically in cancer More > Graphic Abstract

Qifen Li, Yuanbo Hou^*, Yongwen Yang, Liting Zhang, Xiaoxiao Yan

Journal of Renewable Materials, Vol.11, No.8, pp. 3333-3350, 2023, DOI:10.32604/jrm.2023.027464 - 26 June 2023

Abstract Reducing CO₂ to produce methane through microbial electrolytic cell (MEC) is one of the important methods of CO₂ resource utilization. In view of the problem of low methanogenesis rate and weak CO₂ conversion rate in the reduction process, the flow field environment of the cathode chamber is changed by changing the upper gas circulation rate and the lower liquid circulation rate of the cathode chamber to explore the impact on the reactor startup and operation and products. The results showed that under certain conditions, the CO₂ consumption and methane production rate could be increased by changing the… More >

SHA ZHU^#, NANWEI XU^#, JIAYU LIANG, FENGNIAN ZHAO, ZILIN WANG, YUCHAO NI, JINDONG DAI, JINGE ZHAO, XINGMING ZHANG, JUNRU CHEN, GUANGXI SUN, PENGFEI SHEN^*, HAO ZENG^*

Oncology Research, Vol.31, No.4, pp. 605-614, 2023, DOI:10.32604/or.2023.028321 - 25 June 2023

Abstract Background: KMT2 (lysine methyltransferase) family enzymes are epigenetic regulators that activate gene transcription. KMT2C is mainly involved in enhancer-associated H3K4me1, and is also one of the top mutated genes in cancer (6.6% in pan-cancer). Currently, the clinical significance of KMT2C mutations in prostate cancer is understudied. Methods: We included 221 prostate cancer patients diagnosed between 2014 and 2021 in West China Hospital of Sichuan University with cell-free DNA-based liquid biopsy test results in this study. We investigated the association between KMT2C mutations, other mutations, and pathways. Furthermore, we evaluated the prognostic value of KMT2C mutations, measured by… More >

Jiuxuan Liu, Yong Zeng^*, Xueya Zhao, Hongbo Chen, Bin Yan, Qian Lu

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.10, pp. 2499-2518, 2023, DOI:10.32604/fdmp.2023.028413 - 25 June 2023

Abstract

A method combining computational fluid dynamics (CFD) and an analytical approach is proposed to develop a prediction model for the variable thickness of the spray-induced liquid film along the surface of a cylindrical workpiece. The numerical method relies on an Eulerian-Eulerian technique. Different cylinder diameters and positions and inclinations of the spray gun are considered and useful correlations for the thickness of the liquid film and its distribution are determined using various data fitting algorithms. Finally, the reliability of the proposed method is verified by means of experimental tests where the robot posture is changed. The

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Gang Xiang^1,2, Xiaoyu Cheng³, Wei He^3,4,*, Peng Han³

Computer Systems Science and Engineering, Vol.47, No.1, pp. 273-298, 2023, DOI:10.32604/csse.2023.037892 - 26 May 2023

Abstract A liquid launch vehicle is an important carrier in aviation, and its regular operation is essential to maintain space security. In the safety assessment of fluid launch vehicle body structure, it is necessary to ensure that the assessment model can learn self-response rules from various uncertain data and not differently to provide a traceable and interpretable assessment process. Therefore, a belief rule base with interpretability (BRB-i) assessment method of liquid launch vehicle structure safety status combines data and knowledge. Moreover, an innovative whale optimization algorithm with interpretable constraints is proposed. The experiments are carried out… More >

Wenqi Zhao¹, Wenbin Sun^1,2,3,*, Zhenbo Cao¹, Jianbang Hao¹

Journal of Renewable Materials, Vol.11, No.7, pp. 3073-3089, 2023, DOI:10.32604/jrm.2023.026409 - 05 June 2023

Abstract Mine grouting reinforcement and water plugging projects often require large amounts of grouting materials. To reduce the carbon emission of grouting material production, improve the utilization of solid waste from mining enterprises, and meet the needs of mine reinforcement and seepage control, a double-liquid grouting material containing a high admixture of coal gangue powder/bottom ash geopolymer was studied. The setting time, fluidity, bleeding rate, and mechanical properties of grouting materials were studied through laboratory tests, and SEM analyzed the microstructure of the materials. The results show that the total mixture of calcined gangue does not More >

ALESSANDRO GOZZETTI^*, MONICA BOCCHIA

Oncology Research, Vol.31, No.3, pp. 271-274, 2023, DOI:10.32604/or.2023.028668 - 22 May 2023

Abstract Novel drug availability has increased the depth of response and revolutionised the outcomes of multiple myeloma patients. Minimal residual disease evaluation is a surrogate for progression-free survival and overall survival and has become widely used not-only in clinical trials but also in daily patient management. Bone marrow aspiration is the gold standard for response evaluation, but due to the patchy nature of myeloma, false negatives are possible. Liquid biopsy and blood-based minimal residual disease evaluation consider circulating plasma cells, mass spectrometry or circulating tumour DNA. This approach is less invasive, can provide a more comprehensive More >

Qi Zhuang^a,* , Dong Liu^b, Bo Liu^c, Mei Liu^a

Frontiers in Heat and Mass Transfer, Vol.20, pp. 1-6, 2023, DOI:10.5098/hmt.20.13

Abstract In the actual operation of wet gas pipeline, liquid accumulation is easy to form in the low-lying and uphill sections of the pipeline, which leads to a series of problems such as reduced pipeline transportation efficiency, increased pipeline pressure drop, hydrate formation, slug flow and intensified corrosion in the pipeline. Accurate calculation of liquid holdup is of great significance to the research of flow pattern identification, pipeline corrosion evaluation and prediction, and gas pipeline transportation efficiency calculation. Based on the experimental data of liquid holdup in horizontal pipeline, a commonly used BP neural network (BPNN)… More >

HONG YANG^1,2, WAN LI^1,2, LIWEN REN^1,2, YIHUI YANG^1,2, YIZHI ZHANG^1,2, BINBIN GE^1,2, SHA LI^1,2, XIANGJIN ZHENG^1,2, JINYI LIU^1,2, SEN ZHANG^1,2, GUANHUA DU^1,2, BO TANG³, HONGQUAN WANG³, JINHUA WANG^1,2,*

Oncology Research, Vol.31, No.2, pp. 83-99, 2023, DOI:10.32604/or.2023.028905 - 10 April 2023

Abstract Pancreatic cancer is a malignant disease characterized by low survival and high recurrence rate, whose patients are mostly at the stage of locally advanced or metastatic disease when first diagnosed. Early diagnosis is particularly important because prognostic/predictive markers help guide optimal individualized treatment regimens. So far, CA19-9 is the only biomarker for pancreatic cancer approved by the FDA, but its effectiveness is limited by low sensitivity and specificity. With recent advances in genomics, proteomics, metabolomics, and other analytical and sequencing technologies, the rapid acquisition and screening of biomarkers is now possible. Liquid biopsy also occupies More > Graphic Abstract