Thomas Makris, Georgios Stavroulakis, Demetrios Papadopoulos, Ioannis Paizis, Panagiota Krespi, Caterina Tsoukala, Antonios Hatzizacharias, Vasilios Votteas
European Cytokine Network, Vol.17, No.2, pp. 137-141, 2006
Abstract White coat hypertension (WCH) or isolated clinic hypertension is generally accepted to be a benign
condition, although some reports have suggested that it may be associated with an increased cardiovascular event
rate or other cardiovascular alterations. It has been previously shown that essential hypertension (EH) is
associated with abnormalities in haemostatic/fibrinolytic balance and endothelial function. The aim of our study
was to assess the impact of WCH on fibrinolytic balance and endothelial function by measuring plasma levels of
plasminogen activator inhibitor-1 (PAI-1), tissue plasminogen activator antigen (tPA), fibrinogen, and thrombomodulin.
These markers were determined in More >