Guila Delouuya^1,2, Carole Lambert^1,2, Jean-Paul Bahary^1,2, Marie-Claude Beauchemin^1,2, Maroie Barkati^1,2, Cynthia Ménard^1,2, Daniel Taussky^1,2

Canadian Journal of Urology, Vol.24, No.3, pp. 8822-8826, 2017

Abstract Introduction: We tested different classification systems in order to separate intermediate-risk prostate cancers into prognostic groups. We then examined which groups were most suited for either prostate seed brachytherapy (PB) or external beam radiotherapy (EBRT).
Materials and methods: We selected patients with D'Amico intermediate-risk prostate cancer who were treated exclusively with either PB or EBRT. Patients were excluded if they had received androgen deprivation therapy in combination with EBRT or a follow up of < 30 months without recurrence. The Kaplan-Meier method was used to compare groups.
Results: Our sample consisted of 475 patients treated from July 2002-September… More >

Ram A. Pathak¹, David D. Thiel¹, Alexander Parker², Michael G. Heckman³, Julia E. Crook³, Nancy N. Diehl³, Andrea Tavlarides², Scott W. Alford¹, Todd C. Igel¹

Canadian Journal of Urology, Vol.24, No.3, pp. 8795-8801, 2017

Abstract Introduction: To compare visual analog scale (VAS) pain scores between patients with a 2-minute versus 10-minute delay of peri-prostatic lidocaine injection prior to transrectal ultrasound-guided prostate biopsies (TRUS-bx).
Materials and methods: Eighty patients who underwent standard 12-core TRUS-bx by a single surgeon were prospectively randomized into four different treatment arms: bibasilar injection with a 2-minute delay, bibasilar injection plus a single apical injection with a 2-minute delay, bibasilar injection with a 10-minute delay, and bibasilar injection plus a single apical injection with a 10-minute delay. Patients were asked to report their level of pain on the VAS… More >

Rosa Park, Christopher Rjepaj, Kathleen Lehman, Jay D. Raman

Canadian Journal of Urology, Vol.24, No.6, pp. 9103-9106, 2017

Abstract Introduction: The Clavien-Dindo (CD) and Comprehensive Complication Index (CCI) are two grading systems that annotate adverse events following surgical procedures. We compare these two classification systems in a cohort of patients undergoing radical nephroureterectomy (RNU).
Materials and methods: The charts of 110 consecutive RNU patients were reviewed for complications occurring within 30 days of surgery. Grading by the CD classification system and values for CCI were calculated. Bivariate and multivariate analysis identified associations between perioperative variables and complications, as well as relationship to hospital length of stay.
Results: Sixty-seven men and 43 women with a median age of… More >

Ling Liu, Nianfeng Li, Qi Zhang, Jixiang Zhou, Ling Lin, Xinxin He

Oncology Research, Vol.25, No.9, pp. 1607-1616, 2017, DOI:10.3727/096504017X14938093512742

Abstract Transforming growth factor-b (TGF-β) and ERK signaling have been implicated in various human cancers including hepatocellular carcinoma, but the underlying mechanism remains largely unclear. In this study, we aimed to explore the role of ERK1/2 in the regulation of TGF-β’s promoting and suppressive activities in HCC cells. Our data showed that treatment with TGF-β1 enhanced invasion and epithelial–mesenchymal transition (EMT) in HCC HepG2 cells, accompanied with increased MMP9 production and activation of Smad2/3 and ERK1/2, but inhibited tumor cell proliferation. These effects were eliminated by treatment with SB431542, a TGF-β inhibitor. Afterward, treatment with the… More >

Kevin W. Irick^*

Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-7, 2017, DOI:10.5098/hmt.8.2

Abstract The Single-sided Guarded Hot Plate Method for Comparative Testing of Thermal Radiation Barriers in Vacuum was used to evaluate the performance of a variety of aerogel insulation specimens manufactured by Aspen Aerogels® against one another and against multi-layer insulation (MLI). Testing at the Air Force Research Laboratory (AFRL) shows that the effective thermal resistance, R_e, of all tested aerogel specimens are virtually bounded by the performance of 5-layer and 10-layer MLI specimens over a mean specimen temperature, T_m, range of about 270K to 315K. More >

Driss Achemlal^a,† , Mohammed Sriti^b , Mohamed El Haroui^b , Elyazid Flilihi^b , Mounir Kriraa^a

Frontiers in Heat and Mass Transfer, Vol.9, pp. 1-10, 2017, DOI:10.5098/hmt.9.34

Abstract In this paper we study the combined free convection, due to thermal and species diffusion, of a viscous incompressible non Newtonian fluid over a vertical plate embedded in a saturated porous medium with three thermal states of the surface and a constant concentration in the presence of a chemical reaction. The effect of temperature dependent viscosity is also investigated. The Ostwald-de Waele power-law model is used to characterize the non-Newtonian fluid behavior. The governing boundary layer equations along with the boundary conditions are first cast into a dimensionless form by a unique similarity transformation and More >

K. Ganesh Kumar¹ , G.K. Ramesh^2,*, B.J. Gireesha¹

Frontiers in Heat and Mass Transfer, Vol.9, pp. 1-8, 2017, DOI:10.5098/hmt.9.32

Abstract The present article addresses the double-diffusive convection flow of the Casson fluid with thermal radiation. With suitable independent transformations, the governing partial differential equations are first transformed into ordinary differential equations. The converted equations are solved numerically by using Runge-Kutta-Fehlberg forth-fifth technique (RKF45 Method) via shooting technique. The eects of the emerging parameters, the skin friction coecient, the Nusselt number, and the Sherwood number are analyzed on the dimensionless velocities, temperature, and concentration fields. Outcome shows that buoyancy forces due to temperature difference suppress the skin friction whereas it will enhance the local Nusselt and More >

T. Sravan Kumar, B. Rushi Kumar^*

Frontiers in Heat and Mass Transfer, Vol.9, pp. 1-7, 2017, DOI:10.5098/hmt.9.13

Abstract In this work, the steady natural convective boundary layer flow of nanofluid and heat transfer over a stretching sheet in the presence of a uniform transverse magnetic field is investigated. We consider two different base fluids and three different nanoparticles were examined as nanofluid. A new model was used in the simulation of nanofluid. Similarity transformations are used to obtain a system of nonlinear ordinary differential equations. The resulting equations are solved numerically by shooting method with Runge-Kutta fourth order scheme (MATLAB package). The effects of various parameters describing the transport in the presence of More >

Rahul H. Rathod^1,2, Brittney Jurgen^1,2, Rose A. Hamershock³, Kevin G. Friedman^1,2, Audrey C. Marshall^1,2, Mihail Samnaliev⁴, Dionne A. Graham³, Kathy Jenkins^1,2, James E. Lock^1,2, Andrew J. Powell^1,2

Congenital Heart Disease, Vol.12, No.6, pp. 768-776, 2017, DOI:10.1111/chd.12508

Abstract Background: Standardized Clinical Assessment and Management Plans (SCAMPs) are a quality improvement initiative designed to reduce unnecessary utilization, decrease practice variation, and improve patient outcomes. We created a novel methodology, the SCAMP managed episode of care (SMEOC), which encompasses multiple encounters to assess the impact of the arterial switch operation (ASO) SCAMP on total costs.
Methods: All ASO SCAMP patients (dates March 2009 to July 2015) were compared to a control group of ASO patients (January 2001 to February 2009). Patients were divided into “younger” (<2 years) and “older” (2–18 years) subgroups. Utilization included all cardiology visits,… More >

Monique M. Gardner, Meryl S. Cohen

Congenital Heart Disease, Vol.12, No.6, pp. 783-786, 2017, DOI:10.1111/chd.12506

Abstract Background: Noncompaction is a poorly understood form of cardiomyopathy that typically affects the left ventricle and may be associated with congenital heart disease. Right ventricular noncompaction (RVNC) may occur when the left ventricle is affected but is rarely seen in isolation. RVNC may have clinical significance affecting surgical and long-term outcomes. We describe the diagnosis and clinical course in three patients at our institution.
Methods: We performed a retrospective review of patients diagnosed with RVNC over a 12- month period at our institution and reviewed their imaging and clinical course.
Results: Three patients were identified. All had diagnosis… More >