ANURADHA SEHRAWAT AND VIJAY KUMAR^*

BIOCELL, Vol.36, No.2, pp. 63-71, 2012, DOI:10.32604/biocell.2012.36.063

Abstract The flower of Butea monosperma (Lam.) (Fabaceae) has been used in traditional Indian medicine in the treatment of many ailments including liver disorders. To understand the pharmacological basis of its beneficial effects, the extracts of dried flowers in water, methanol, butanol, ethyl acetate and acetone were evaluated for free radical scavenging and pro-apoptotic activities in cell cultures (human hepatoma Huh-7 cell line and immortalized AML-12 mouse hepatocytes). Butrin and butein -the active constituents of flower extracts- were used as reference molecules. The levels of cell injury markers like lactate dehydrogenase, glutathione and lipid peroxidation and primary… More >

RANA IMANI¹, SHAHRIAR HOJJATI EMAMI¹, HOSSEIN FAKHRZADEH², NAFISEH BAHEIRAEI¹, ALI M SHARIFI^{* 2,3,4}

BIOCELL, Vol.36, No.1, pp. 37-45, 2012, DOI:10.32604/biocell.2012.36.037

Abstract The ultimate goal of tissue engineering is to design and fabricate functional human tissues that are similar to natural cells and are capable of regeneration. Preparation of cell aggregates is one of the important steps in 3D tissue engineering technology, particularly in organ printing. Two simple methods, hanging drop (HD) and conical tube (CT) were utilized to prepare cell aggregates. The size and viability of the aggregates obtained at different initial cell densities and pre-culture duration were compared. The proliferative ability of the cell aggregates and their ability to spread in culture plates were also… More >

C. Jiang^1,2, X. Han¹, D. Li³

CMC-Computers, Materials & Continua, Vol.27, No.3, pp. 275-304, 2012, DOI:10.3970/cmc.2011.027.275

Abstract For optimization or decision-making problems with interval uncertainty, the interval comparison relation plays a very important role, as only based on it a better or best decision can be determined. In this paper, a new kind of interval comparison relation termed as reliability-based possibility degree of interval is proposed to give quantitative evaluations on "how much better" of one interval than another, which is more suitable for engineering reliability analysis and numerical computation than the existing relations. In the new relation, the range of the comparing values is extended into the whole real number field, and the precise comparison More >

N. Thai-Quang¹, N. Mai-Duy¹, C.-D Tran¹, T. Tran-Cong¹

CMES-Computer Modeling in Engineering & Sciences, Vol.89, No.3, pp. 189-220, 2012, DOI:10.3970/cmes.2012.089.189

Abstract In this paper, the alternating direction implicit (ADI) method reported in [You(2006)] for the convection-diffusion equation is implemented in the context of compact integrated radial basis function (CIRBF) approximations. The CIRBF approximations are constructed over 3-point stencils, where extra information is incorporated via two forms: only nodal second-order derivative values (Scheme 1), and both nodal first- and second-order derivative values (Scheme 2). The resultant algebraic systems are sparse, especially for Scheme 2 (tridiagonal matrices). Several steady and non-steady problems are considered to verify the present schemes and to compare their accuracy with some other ADI More >

A. Ramachandra Murthy¹ , G.S. Palani¹ , Nagesh R. Iyer¹ , Smitha Gopinath¹ and V. Ramesh Kumar¹

CMES-Computer Modeling in Engineering & Sciences, Vol.86, No.5, pp. 409-434, 2012, DOI:10.3970/cmes.2012.086.409

Abstract This paper presents the details of projectile impact on reinforced concrete structural components. Nonlinear explicit transient dynamic analysis has been carried out by using finite element method. Concrete damage model has been employed to represent the nonlinear behaviour of target under impact load. Various methods of modeling of reinforcement have been explained. A brief note on equation of state for concrete, contact algorithms and nonlinear explicit transient dynamic analysis has been given. Numerical studies have been carried out to compute the response of concrete target due to impact of projectile. The computed penetration depth have More >

Souli, M.¹, Gabrys, J.²

CMES-Computer Modeling in Engineering & Sciences, Vol.85, No.2, pp. 177-192, 2012, DOI:10.3970/cmes.2012.085.177

Abstract Bird impacts on aircraft are very common and cause significant safety threats to commercial and military aircraft. According to FAA ( Federal American Aviation) regulations, aircraft should be able to land safely following specified types of bird impact on components such as radomes, windshields, engines leading edge structures and other exposed components. Thus exposed components are required to be certified for bird impact. In order to evaluate whether the aircraft is compliant to FAA requirements, several experimental tests and numerical simulations of bird impact on components need to be preformed. This paper presents an experimental More >

N. Thai-Quang¹, K. Le-Cao¹, N. Mai-Duy¹, T. Tran-Cong¹

CMES-Computer Modeling in Engineering & Sciences, Vol.84, No.6, pp. 528-558, 2012, DOI:10.3970/cmes.2012.084.528

Abstract This study is concerned with the development of integrated radial-basis-function (IRBF) method for the simulation of two-dimensional steady-state incompressible viscous flows governed by the pressure-velocity formulation on Cartesian grids. Instead of using low-order polynomial interpolants, a high-order compact local IRBF scheme is employed to represent the convection and diffusion terms. Furthermore, an effective boundary treatment for the pressure variable, where Neumann boundary conditions are transformed into Dirichlet ones, is proposed. This transformation is based on global 1D-IRBF approximators using values of the pressure at interior nodes along a grid line and first-order derivative values of… More >

T.-T. Hoang-Trieu¹, N. Mai-Duy¹, T. Tran-Cong¹

CMES-Computer Modeling in Engineering & Sciences, Vol.84, No.2, pp. 171-204, 2012, DOI:10.3970/cmes.2012.084.171

Abstract In this paper, new compact local stencils based on integrated radial basis functions (IRBFs) for solving fourth-order ordinary differential equations (ODEs) and partial differential equations (PDEs) are presented. Five types of compact stencils - 3-node and 5-node for 1D problems and 5×5-node, 13-node and 3×3 -node for 2D problems - are implemented. In the case of 3-node stencil and 3×3-node stencil, nodal values of the first derivative(s) of the field variable are treated as additional unknowns (i.e. 2 unknowns per node for 3-node stencil and 3 unknowns per node for 3×3-node stencil). The integration constants… More >

Weiwei Gong, Yan Liu, Xiong Zhang, Honglei Ma

CMES-Computer Modeling in Engineering & Sciences, Vol.83, No.5, pp. 527-546, 2012, DOI:10.3970/cmes.2012.083.527

Abstract Owing to its low density and good energy absorption capability, aluminum foam is an excellent protective material for spacecraft against debris impact. However, because of its complicated microstructure, it is very difficult to generate a FEM mesh accounting for the real microstructure of the alluminum foam. On the contrary, it is very easy to model three-dimensional problems with very complicated geometry with meshfree/meshless methods. Furthermore, the material point method has obvious advantages in modeling problems involving extreme large deformation problems like hypervelocity impact problem. In this paper, a three-dimensional material point model accounting for the More >

Li Shan, Ning Cui, Ming Cheng, Kaixin Liu

CMES-Computer Modeling in Engineering & Sciences, Vol.83, No.4, pp. 353-384, 2012, DOI:10.3970/cmes.2012.083.353

Abstract In the present paper, a combined scheme of discrete element method (DEM) and meshless method for numerical simulation of impact problems is proposed. Based on the basic principle of continuum mechanics, an axisymmetric DEM framework is established for modeling the elastoplastic behavior of solid materials. Failure criteria are introduced to model the transformation from a continuum to a discontinuum. The friction force between contact elements is also considered after the failure appears. So our scheme can calculate not only the behavior of continuum and discontinuum, but also the transformation process from a continuum to a More >