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  • Open Access

    ARTICLE

    Efficient Clustering Network Based on Matrix Factorization

    Jieren Cheng1,3, Jimei Li1,3,*, Faqiang Zeng1,3, Zhicong Tao1,3, Yue Yang2,3

    CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 281-298, 2024, DOI:10.32604/cmc.2024.051816 - 18 July 2024

    Abstract Contrastive learning is a significant research direction in the field of deep learning. However, existing data augmentation methods often lead to issues such as semantic drift in generated views while the complexity of model pre-training limits further improvement in the performance of existing methods. To address these challenges, we propose the Efficient Clustering Network based on Matrix Factorization (ECN-MF). Specifically, we design a batched low-rank Singular Value Decomposition (SVD) algorithm for data augmentation to eliminate redundant information and uncover major patterns of variation and key information in the data. Additionally, we design a Mutual Information-Enhanced More >

  • Open Access

    REVIEW

    The pathogenesis of chronic subdural hematoma in the perspective of neomembrane formation and related mechanisms

    MINGYUE HUANG1,#, JUNFEI DAI1,#, XIANLIANG ZHONG2, JIN WANG2, JIANZHONG XU2, BO DU2,*

    BIOCELL, Vol.48, No.6, pp. 889-896, 2024, DOI:10.32604/biocell.2024.050097 - 10 June 2024

    Abstract Chronic subdural hematoma (CSDH) is a disease characterized by capsuled blood products that progressively occupy the intracranial space, causing intracranial hypertension and compression in the brain. CSDH frequently occurs in all demographics, especially in the elderly, but the pathogenesis of CSDH remains unclear. In this review, we discuss the origin, development, and current treatment strategies of CSDH. For the first time, we analyzed the cellular and molecular compositions of hematoma membranes with a focus on neomembrane formation, a complex early-stage interactive event in hematoma pathogenesis. We hypothesize that in patients with CSDH, dural border cells… More >

  • Open Access

    ARTICLE

    Path-Based Clustering Algorithm with High Scalability Using the Combined Behavior of Evolutionary Algorithms

    Leila Safari-Monjeghtapeh1, Mansour Esmaeilpour2,*

    Computer Systems Science and Engineering, Vol.48, No.3, pp. 705-721, 2024, DOI:10.32604/csse.2024.044892 - 20 May 2024

    Abstract Path-based clustering algorithms typically generate clusters by optimizing a benchmark function. Most optimization methods in clustering algorithms often offer solutions close to the general optimal value. This study achieves the global optimum value for the criterion function in a shorter time using the minimax distance, Maximum Spanning Tree “MST”, and meta-heuristic algorithms, including Genetic Algorithm “GA” and Particle Swarm Optimization “PSO”. The Fast Path-based Clustering “FPC” algorithm proposed in this paper can find cluster centers correctly in most datasets and quickly perform clustering operations. The FPC does this operation using MST, the minimax distance, and… More >

  • Open Access

    ARTICLE

    CMAES-WFD: Adversarial Website Fingerprinting Defense Based on Covariance Matrix Adaptation Evolution Strategy

    Di Wang, Yuefei Zhu, Jinlong Fei*, Maohua Guo

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2253-2276, 2024, DOI:10.32604/cmc.2024.049504 - 15 May 2024

    Abstract Website fingerprinting, also known as WF, is a traffic analysis attack that enables local eavesdroppers to infer a user’s browsing destination, even when using the Tor anonymity network. While advanced attacks based on deep neural network (DNN) can perform feature engineering and attain accuracy rates of over 98%, research has demonstrated that DNN is vulnerable to adversarial samples. As a result, many researchers have explored using adversarial samples as a defense mechanism against DNN-based WF attacks and have achieved considerable success. However, these methods suffer from high bandwidth overhead or require access to the target… More >

  • Open Access

    REVIEW

    HIFs in hypoxic regulation of the extracellular matrix: focus on little-known player HIF-3

    ALEKSANDRA GORNOSTAEVA, LUDMILA BURAVKOVA, MARGARITA LOBANOVA, ELENA ANDREEVA*

    BIOCELL, Vol.48, No.5, pp. 677-692, 2024, DOI:10.32604/biocell.2024.048873 - 06 May 2024

    Abstract The structural and associated molecules of the extracellular matrix (ECM) complex is an important component of the local milieu of cells, both for maintaining their functions and homeostasis. It is a dynamic structure that is finely tuned to changes in the microenvironment. One of these factors is hypoxia, which can arise in tissues due to physiological or pathological effects. As a result of the hypoxic effect, the properties of the ECM are significantly modified, stiffness increases, the balance between degradation and synthesis of structural proteins shifts, and the deposition of biologically active mediators’ changes. Hypoxia-inducible… More >

  • Open Access

    ARTICLE

    miR-200b-3p accelerates progression of pituitary adenomas by negatively regulating expression of RECK

    XIAOXI WANG1, YANFEI JIA2, QIANG LI2, QIANG YANG2, YINGFENG LIU1, BEIFENG WEI1, XIANG NIU1, YINJIE ZHANG1, XIAODONG LUO2, ZIYU ZHAO1,*, PENG WANG1,*

    Oncology Research, Vol.32, No.5, pp. 933-941, 2024, DOI:10.32604/or.2023.042581 - 23 April 2024

    Abstract MicroRNA (miR)-200b-3p has been associated with many tumors, but its involvement in pituitary adenoma is unclear. This study investigated the molecular mechanism underlying miR-200b-3p regulation in pituitary adenomas to provide a theoretical basis for treatment. Bioinformatics was used to analyze pituitary adenoma-related genes and screen new targets related to RECK and miRNA. As well, the relationship between miR-200b-3p and RECK protein was verified using a double-luciferase reporter gene assay. The expression of miR-200b-3p in clinical samples was analyzed by in situ hybridization. Transfection of the miR-200b-3p inhibitor and small interfering-RECK (si-RECK) was verified by qPCR. GH3… More >

  • Open Access

    ARTICLE

    Matrix Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF)-Mass Spectrometry and 13C-NMR-Identified New Compounds in Paraberlinia bifoliolata (Ekop-Beli) Bark Tannins

    Liliane Nga1, Benoit Ndiwe1,2, Achille Bernard Biwolé1, Antonio Pizzi3,*, Jean Jalin Eyinga Biwole1, Joseph Zobo Mfomo1

    Journal of Renewable Materials, Vol.12, No.3, pp. 553-568, 2024, DOI:10.32604/jrm.2023.046568 - 11 April 2024

    Abstract Extracts of plant origin, particularly tannins, are attracting growing interest for the sustainable development of materials in the industrial sector. The discovery of new tannins is therefore necessary. The aim of this work was to contribute to the understanding of the properties of Paraberlinia bifoliolata tannin by Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectroscopy MALDI-TOF/MS and Carbon 13 Nuclear Magnetic Resonance (13C NMR). The chemical composition of tannin extracted from Paraberlinia bifoliolata bark was determined, as was the mechanical strength of the resin hardened with Acacia nilotica extracts. Yield by successive water extraction was 35%. MALDI-TOF/MS… More >

  • Open Access

    REVIEW

    Overview of Jute Fibre as Thermoplastic Matrix Polymer Reinforcement

    Tezara Cionita1,*, Mohammad Hazim Mohamad Hamdan2, Januar Parlaungan Siregar3,4,*, Deni Fajar Fitriyana5, Ramli Junid6, Wong Ling Shing7, Jamiluddin Jaafar8, Agustinus Purna Irawan9, Teuku Rihayat10, Rifky Ismail11, Athanasius Priharyoto Bayuseno11, Emilianus Jehadus12

    Journal of Renewable Materials, Vol.12, No.3, pp. 457-483, 2024, DOI:10.32604/jrm.2024.045814 - 11 April 2024

    Abstract Recent decades have seen a substantial increase in interest in research on natural fibres that is aligned with sustainable development goals (SDGs). Due to their renewable resources and biodegradability, natural fiber-reinforced composites have been investigated as a sustainable alternative to synthetic materials to reduce the usage of hazardous waste and environmental pollution. Among the natural fibre, jute fibre obtained from a bast plant has an increasing trend in the application, especially as a reinforcement material. Numerous research works have been performed on jute fibre with regard to reinforced thermoset and thermoplastic composites. Nevertheless, current demands More >

  • Open Access

    ARTICLE

    NFT Security Matrix: Towards Modeling NFT Ecosystem Threat

    Peng Liao1, Chaoge Liu2, Jie Yin1,3,*, Zhi Wang2, Xiang Cui2

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3255-3285, 2024, DOI:10.32604/cmes.2024.043855 - 11 March 2024

    Abstract Digital assets have boomed over the past few years with the emergence of Non-fungible Tokens (NFTs). To be specific, the total trading volume of digital assets reached an astounding $55.5 billion in 2022. Nevertheless, numerous security concerns have been raised by the rapid expansion of the NFT ecosystem. NFT holders are exposed to a plethora of scams and traps, putting their digital assets at risk of being lost. However, academic research on NFT security is scarce, and the security issues have aroused rare attention. In this study, the NFT ecological process is comprehensively explored. This… More >

  • Open Access

    ARTICLE

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

    PING YANG1,2,3, YUANXIANG LAN1,2, ZHONG ZENG1,2, YAN WANG1,2, HECHUN XIA1,2,*

    BIOCELL, Vol.48, No.1, pp. 149-162, 2024, DOI:10.32604/biocell.2023.042367 - 30 January 2024

    Abstract Background: As a form of biological therapy, placenta-derived mesenchymal stem cells (PDMSCs) exhibit considerable promise in addressing the complex pathological processes of traumaticbrain injury (TBI) due to their multi-target and multi-pathway mode of action. Material & Methods: This study investigates the protective mechanisms and benefits of PDMSCs in mitigating the effects of controlled cortical impact (CCI) in rats and glutamate-induced oxidative stress injury in HT22 cells in vitro. Our primary objective is to provide evidence supporting the clinical application of PDMSCs. Results: In the in vivo arm of our investigation, we observed a swift elevation of matrix metalloproteinase-9… More > Graphic Abstract

    Placenta-derived mesenchymal stem cells attenuate secondary brain injury after controlled cortical impact in rats by inhibiting matrix metalloproteinases

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