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  • Open Access

    ARTICLE

    β-Cyclodextrin-Based Nitrosoglutathione Improves the Storage Quality of Peach by Regulating the Metabolism of Endogenous Nitric Oxide, Hydrogen Sulfide, and Phenylpropane

    Chen Chen, Shuhua Zhu*

    Phyton-International Journal of Experimental Botany, Vol.92, No.4, pp. 1091-1107, 2023, DOI:10.32604/phyton.2023.026331 - 06 January 2023

    Abstract Nitrosoglutathione (GSNO) and β-cyclodextrin (β-CD) exhibit positive roles in regulating fruit quality. However, there are few reports about the effects of GSNO and β-CD on enhancing storability and boosting nitric oxide (NO), hydrogen sulfide (H2S), and phenylpropane metabolism in fruits during storage. “Xintaihong” peach were treated with 0.5, 1.0, 1.5 mmol L−1 GSNO in 0.5% (w/v) β-CD solution (GSNO/β-CD). The effects of GSNO/β-CD on endogenous NO, H2S, and phenylpropane metabolism were investigated. Treatment with GSNO/β-CD increased the color difference of peach and inhibited the increase of respiratory intensity, weight loss, and relative conductivity. Treatment with 1.0 mmol… More >

  • Open Access

    REVIEW

    Translocation and transformation of engineered nanomaterials in plant cells and their effect on metabolism

    WEICHEN ZHAO1, PINGFAN ZHOU1, BENZHEN LOU1, YAQI JIANG1, YUANBO LI1, MINGSHU LI1, NOMAN SHAKOOR1, YUKUI RUI1,2,3,4,*

    BIOCELL, Vol.47, No.3, pp. 493-502, 2023, DOI:10.32604/biocell.2023.025740 - 03 January 2023

    Abstract As the climate worsens and the demand for food grows, so does the interest in nanoagriculture. The interaction between plants and nanomaterials (NMs) has been extensively and intensively examined. However, stopping at the outcome of a phenomenon is often insufficient. Therefore, we introduce three important processes of nanoparticle-plant interactions: translocation, transformation, and plant metabolism. During the migration of nanoparticles, size and surface electrical properties are the main determining factors. Additionally, the interaction of nanoparticles with cell membranes is another key aspect of research. The transformation of nanoparticles in plants is mainly due to redox substances. More >

  • Open Access

    ARTICLE

    A model based on eight iron metabolism-related genes accurately predicts acute myeloid leukemia prognosis

    ZHANSHU LIU1, XI HUANG2,*

    BIOCELL, Vol.47, No.3, pp. 593-605, 2023, DOI:10.32604/biocell.2023.024148 - 03 January 2023

    Abstract Purpose: Iron metabolism maintains the balance between iron absorption and excretion. Abnormal iron metabolism can cause numerous diseases, including tumor. This study determined the iron metabolism-related genes (IMRGs) signature that can predict the prognosis of acute myeloid leukemia (AML). The roles of these genes in the immune microenvironment were also explored. Methods: A total of 514 IMRGs were downloaded from the Molecular Characteristics Database (MSigDB). IMRGs related to AML prognosis were identified using Cox regression and LASSO analyses and were used to construct the risk score model. AML patients were stratified into high-risk groups (cluster 1)… More >

  • Open Access

    ARTICLE

    Silicon and Nitric Oxide-Mediated Regulation of Growth Attributes, Metabolites and Antioxidant Defense System of Radish (Raphanus sativus L.) under Arsenic Stress

    Savita Bhardwaj1, Tunisha Verma1, Ali Raza2,*, Dhriti Kapoor1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.3, pp. 763-782, 2023, DOI:10.32604/phyton.2023.025672 - 29 November 2022

    Abstract

    Arsenic (As) contaminated food chains have emerged as a serious public concern for humans and animals and are known to affect the cultivation of edible crops throughout the world. Therefore, the present study was designed to investigate the individual as well as the combined effects of exogenous silicon (Si) and sodium nitroprusside (SNP), a nitric oxide (NO) donor, on plant growth, metabolites, and antioxidant defense systems of radish (Raphanus sativus L.) plants under three different concentrations of As stress, i.e., 0.3, 0.5, and 0.7 mM in a pot experiment. The results showed that As stress reduced the

    More >

  • Open Access

    REVIEW

    Drosophila melanogaster as an indispensable model to decipher the mode of action of neurotoxic compounds

    MONALISA MISHRA1,2,*, PUNYATOYA PANDA1, BEDANTA KUMAR BARIK1, AMRITA MONDAL1, MRUTUNJAYA PANDA1

    BIOCELL, Vol.47, No.1, pp. 51-69, 2023, DOI:10.32604/biocell.2022.023392 - 26 September 2022

    Abstract Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in the later stage of life. Those toxic compounds are termed as a neurotoxicant, which can be a physical factor, a toxin, an infection, radiation, or maybe a drug. The incongruities caused due to a neurotoxicant further depend on the toxicity of the compound. More importantly, the neurotoxicity of the compound is associated with the concentration and the time point of exposure. The neurodevelopmental defect appears depending on the toxicity of the compound. A neurodevelopmental defect may be associated with a More >

  • Open Access

    REVIEW

    The remodeling roles of lipid metabolism in colorectal cancer cells and immune microenvironment

    JIATENG ZHONG1,2, JINGYU GUO1, XINYU ZHANG1, SHUANG FENG1, WENYU DI2, YANLING WANG3,*, HUIFANG ZHU1,*

    Oncology Research, Vol.30, No.5, pp. 231-242, 2022, DOI:10.32604/or.2022.027900 - 03 February 2023

    Abstract Lipid is a key component of plasma membrane, which plays an important role in the regulation of various cell biological behaviors, including cell proliferation, growth, differentiation and intracellular signal transduction. Studies have shown that abnormal lipid metabolism is involved in many malignant processes, including colorectal cancer (CRC). Lipid metabolism in CRC cells can be regulated not only by intracellular signals, but also by various components in the tumor microenvironment, including various cells, cytokines, DNA, RNA, and nutrients including lipids. In contrast, abnormal lipid metabolism provides energy and nutrition support for abnormal malignant growth and distal More >

  • Open Access

    ARTICLE

    A Metabolism-Related Gene Signature Predicts the Prognosis of Breast Cancer Patients: Combined Analysis of High-Throughput Sequencing and Gene Chip Data Sets

    Lei Hu1,2,#, Meng Chen2,3,#, Haiming Dai2,3,4, Hongzhi Wang2,3,4,*, Wulin Yang2,3,4,*

    Oncologie, Vol.24, No.4, pp. 803-822, 2022, DOI:10.32604/oncologie.2022.026419 - 31 December 2022

    Abstract Background and Aim: Hundreds of consistently altered metabolic genes have been identified in breast cancer (BC), but their prognostic value remains to be explored. Therefore, we aimed to build a prediction model based on metabolism-related genes (MRGs) to guide BC prognosis. Methods: Current work focuses on constructing a novel MRGs signature to predict the prognosis of BC patients using MRGs derived from the Virtual Metabolic Human (VMH) database, and expression profiles and clinicopathological data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. Results: The 3-MRGs-signature constructed by SERPINA1, QPRT and PXDNL was found… More >

  • Open Access

    ARTICLE

    Ampelopsin Inhibits Breast Cancer Glucose Metabolism Reprogramming Based on Network Pharmacology and Molecular Docking

    Rong Zeng1,#, Lin Liu1,2,#, Jingshan Zhao1,2,3,#, Wenmei Zhang3, Guohong Zhang1, Yunfeng Li1,2,*

    Oncologie, Vol.24, No.3, pp. 483-498, 2022, DOI:10.32604/oncologie.2022.025148 - 19 September 2022

    Abstract Background: Breast cancer (BC) is the most frequent type of gynecology tumors with high morbidity and mortality. Ampelopsin, the main active compound of Ampelopsis grossedentata, exerts an anti-tumor effect on a variety of cancers. However, the anti-cancer role of ampelopsin in BC remains unclear. The aim of this study is to explore the mechanism of ampelopsin against breast cancer. Materials and Methods: The target genes of ampelopsin in the treatment of breast cancer were determined and analyzed by network pharmacology and molecular docking. Cytoscape software was used to identify the core target genes and construct a protein–protein interaction… More >

  • Open Access

    ARTICLE

    Effects of arbuscular mycorrhizal fungi and plant growth-promoting rhizobacteria on growth and reactive oxygen metabolism of tomato fruits under low saline conditions

    WEI ZHOU, MENGMENG ZHANG, KEZHANG TAO, XIANCAN ZHU*

    BIOCELL, Vol.46, No.12, pp. 2575-2582, 2022, DOI:10.32604/biocell.2022.021910 - 10 August 2022

    Abstract Land salinization is a major form of land degradation, which is not conducive to the growth and quality of fruits and vegetables. Plant salt tolerance can be enhanced by arbuscular mycorrhizal fungi (AMF) or plant growth-promoting rhizobacteria (PGPR). This study examined the effects of inoculation with PGPR singly or in combination with AMF, on the growth and quality of tomato fruits under low saline conditions. Tomatoes were cultivated in a greenhouse with sterilized soil, inoculated with PGPR, AMF, or co-inoculated with PGPR and AMF, and NaCl solution (1%) was added to the soil. The results… More >

  • Open Access

    ARTICLE

    Effects of Drought Stress on Key Enzymes of Carbon Metabolism, Photosynthetic Characteristics and Agronomic Traits of Soybean at the Flowering Stage under Different Soil Substrates

    Shuang Song1, Xiaomei Li2, Xin Wang1, Qi Zhou1, Yongping Li1, Xiaojing Wang1, Shoukun Dong1,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.11, pp. 2475-2490, 2022, DOI:10.32604/phyton.2022.021090 - 12 July 2022

    Abstract Soybean is an important legume food crop, and its seeds are rich in nutrients, providing humans and animals with edible oil and protein feed. However, soybean is sensitive to water requirements, and drought is an important factor limiting soybean yield and quality. This study used Heinong 84 (drought resistant variety) and Hefeng 46 (intermediate variety) as tested varieties planted in chernozem, albic, and black soils. The effects of drought stress on the activities of key enzymes in carbon metabolism and photosynthetic characteristics of soybean were studied during the flowering stage, most sensitive to water. (1)… More >

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