Mustafa Sofikerim¹, İbrahim Gülmez¹, Fatma Tokat², Özlem Er³, İnci Gülmez⁴

Canadian Journal of Urology, Vol.14, No.4, pp. 3643-3645, 2007

Abstract We report a case of epidermoid-cell carcinoma of the lung that developed a metastatic lesion in the penis.A 50-year-old male patient was admitted to our hospital with bloody sputum and cough. He had a left pneumectomy and was diagnosed with epidermoid carcinoma of the lung at stage IIB (T2N1M0). He was started on an adjuvant chemotherapy protocol consisting of cisplatin and paclitaxel. He was admitted to our urology clinic with obstructive symptoms during urination and pain during penile erection.Physical examination revealed a firm, 3 cm x 2 cm palpable mass on the radix of his More >

Muhammad H. Zaman^*

Molecular & Cellular Biomechanics, Vol.4, No.3, pp. 133-142, 2007, DOI:10.3970/mcb.2007.004.133

Abstract Tumor metastasis is the leading cause of nearly all cancer related deaths. While several experimental and computational studies have addressed individual stages of the complex metastasis process, a comprehensive systems-biology model that links various stages of metastasis has not been put forth as of yet. In this paper we discuss the formulation and application of such a model that utilizes basic principles of cell biology, physics and mechanics to study the migratory patterns of tumor cells as they move from the parent tumor site to the connective tissue via the basement membrane. The model is More >

Ithaar H. Derweesh¹, Hazem R. Ismail¹, Cristina Magi-Galluzzi^1,2, Jonathan Hale³, David A. Goldfarb¹

Canadian Journal of Urology, Vol.13, No.5, pp. 3281-3282, 2006

Abstract Introduction: Renal metastasis by non-small cell lung cancer is uncommon and usually described at autopsy.
Case presentation: We report the rare case of a 77-year-old man with localized non-small cell lung carcinoma who underwent extirpative surgery and 2 years later presented with gross hematuria and was noted to have a large infiltrating renal mass on computed tomography.
Conclusions: In patients with a prior history of resected localized non-small cell lung carcinoma, presence of a renal lesion should prompt the clinician to consider the possibility of metastasis. Further evaluation should consider this scenario. More >

Nabeel Al-Brahim¹, Salem Alowami¹, Ian Davis², Dean Daya¹

Canadian Journal of Urology, Vol.11, No.6, pp. 2463-2466, 2004

Abstract An 83- year-old male presented with intermittent hematuria and obstructive symptoms. A CT scan of the abdomen and pelvis showed diffuse thickening of the urinary bladder and a large 10 cm liver mass. Histopathological examination of bladder biopsy demonstrated two distinct lesions. The surface showed non-invasive urothelial carcinoma and the submucosa demonstrated metastatic hepatocellular carcinoma showing bile pigment and expressed Hep Par 1 and CD10. To the best of our knowledge, this is the first case report of synchronous transitional cell carcinoma and metastatic hepatocellular carcinoma of the urinary bladder. More >

W. Kassouf, S. Binsaleh, D. D. Cohen, S. Carrier

Canadian Journal of Urology, Vol.11, No.6, pp. 2461-2462, 2004

Abstract We report a case of collecting duct carcinoma presenting as pyelonephritis with hypercalcemia and metastasis to the ovary. Case management and literature review being presented. More >

M. S. Deshpande, J. N. Kulkarni

Canadian Journal of Urology, Vol.10, No.1, pp. 1770-1771, 2003

Abstract Testicular metastasis presenting as a testicular mass is an extremely rare condition. There are only nine previously reported cases where testicular mass was the first clinical manifestation of underlying malignancy. Here we report a case of metastatic mucin secreting adenocarcinoma in testis presenting as a testicular mass with unknown primary. We have given a brief review of literature about the spread of tumor to testes. More >

Ö. L. Özdal¹, Y. K. Yakupoglu¹, A. Çiçek¹, Ö. Erdem², L. Memis², A. Memis¹

Canadian Journal of Urology, Vol.9, No.2, pp. 1498-1499, 2002

Abstract We report a 55 year old man complaining of painless left testicular swelling that developed over 2 months. The imaging studies revealed an epididymal mass separate from the testicle. The patient underwent left radical orchiectomy. The histopathological examination of the orchiectomy specimen revealed poorly differentiated signet cell metastatic adenocarcinoma. More >