E. Brambilla, A. A. Heck, J. G. Cao, G. T. Toniazzo, L. Petteffi

Canadian Journal of Urology, Vol.14, No.4, pp. 3649-3650, 2007

Abstract Renal infiltration of colon adenocarcinoma is a rare event. The authors present the case report of a 52-year-old female who had a high carcinoembryonic antigen level 18 months after right hemicolectomy and a chemotherapy regimen to treat transverse colon adenocarcinoma. The patient presented with cancer reccurrence after 12 months, and underwent a paraaortic lymphadenoctomy and a second adjuvant chemotherapy with the folfox regimen. Abdomen computerized tomography revealed two solid masses in the right kidney, without evidence of any other metastatic sites. A nephrectomy was performed in the right kidney followed by adjuvant chemotherapy. More >

Mustafa Sofikerim¹, İbrahim Gülmez¹, Fatma Tokat², Özlem Er³, İnci Gülmez⁴

Canadian Journal of Urology, Vol.14, No.4, pp. 3643-3645, 2007

Abstract We report a case of epidermoid-cell carcinoma of the lung that developed a metastatic lesion in the penis.A 50-year-old male patient was admitted to our hospital with bloody sputum and cough. He had a left pneumectomy and was diagnosed with epidermoid carcinoma of the lung at stage IIB (T2N1M0). He was started on an adjuvant chemotherapy protocol consisting of cisplatin and paclitaxel. He was admitted to our urology clinic with obstructive symptoms during urination and pain during penile erection.Physical examination revealed a firm, 3 cm x 2 cm palpable mass on the radix of his More >

Danny M. Rabah

Canadian Journal of Urology, Vol.14, No.4, pp. 3640-3642, 2007

Abstract The traditional treatment of choice for urachal carcinoma has been either an open radical cystectomy or the more recently accepted extended partial cystectomy and umbilectomy. Recently a laparoscopic technique has been reported. We report for the first time a robot-assisted technique for an extended partial cystectomy with en bloc umbilectomy for the management of urachal carcinoma in a 49-year-old man. More >

Frederick P. Mendiola, Kevin C. Zorn, Ofer N. Gofrit, Albert A. Mikhail, Marcelo A. Orvieto, Lambda P. Msezane, Gary D. Steinberg

Canadian Journal of Urology, Vol.14, No.4, pp. 3628-3634, 2007

Abstract Introduction: Radical cystectomy (RC) with urinary diversion remains as one of the more complex urological procedures despite considerable progress in surgical technique. Increasing patient age, along with associated age-related comorbidities, may portend a poor outcome in those undergoing such complicated surgical procedures. Herein, we report our experience with radical cystectomy in the elderly population.
Methods: We retrospectively reviewed our RC results from 1995 to 2003. Patients ≥80 years old were included in this analysis. Perioperative outcomes, as well as overall and disease-free survival were evaluated.
Results: A total of 517 patients underwent RC with urinary diversion during… More >

Canadian Journal of Urology, Vol.14, No.4, pp. 3616-3620, 2007

Abstract Objective: The current standard of care for radiographically identified enhancing renal lesions is surgical removal. However, some of these lesions prove to be benign and did not truly warrant extirpation. Mass size has been traditionally described as a parameter to predict the malignant potential. We compiled our experience with surgically treated renal masses and correlated lesion size with final pathology.
Materials and methods: We performed a retrospective analysis of extirpative renal surgery and resultant renal mass pathology from 1998-January 2006. Nephrectomies performed for non-malignant disease or transitional cell carcinomas were excluded. Renal tumors were staged by the… More >

Can Talug, Jeffrey Mullins, Susan E. Saunders, Stanley Zaslau

Canadian Journal of Urology, Vol.14, No.5, pp. 3707-3709, 2007

Abstract In a patient with a prior history of pancreatitis or abdominal trauma, radiographic imaging may only show abnormalities in the urinary tract. When these patients are first seen with subcapsular or perinephric fluid collections, percutaneous drainage can be both diagnostic and therapeutic. More >

S. Marwaha, P. M. Venner, S. A. North

Canadian Journal of Urology, Vol.14, No.5, pp. 3692-3696, 2007

Abstract Objective: The primary objective was to evaluate the effect of etoposide dose in a 3-day cisplatin/etoposide/bleomycin (PEB) regimen on progression free survival (PFS) and overall survival (OS). Secondary objectives were to determine the impact of a paclitaxel-based salvage regimen on OS and to compare the risk distribution of germ cell patients seen at a tertiary care center to that quoted in the International Germ Cell Consensus Classification (IGCCC).
Methods: A retrospective chart review of all 302 metastatic germ cell patients requiring cisplatin-based chemotherapy between January 1980 and December 2004 was conducted. Data collected on initial treatment… More >

Yoh Matsuoka^1,3, Gaku Arai¹, Hisashi Ishimaru¹, Kentaro Takagi¹, Yuji Ito²

Canadian Journal of Urology, Vol.14, No.6, pp. 3764-3766, 2007

Abstract We report a rare case of primary signet-ring cell carcinoma of the prostate in an advanced stage. A 62-year-old man with serum level of prostate-specific antigen at 364.70 ng/ml was diagnosed as having cT4N1M1c prostatic signet-ring cell carcinoma of Gleason score 5 + 4 = 9. Immunohistochemical examination demonstrated cytoplasmic immunoreactivity to prostate-specific antigen in signet-ring cancer cells. The intracytoplasmic vacuoles in the signet-ring cells showed mucin production with a positive staining with periodic acid-Schiff. Although the patient received hormonal therapy, the disease progressed and lead to death 15 months after the diagnosis. The clinical More >

Kristian T. Schafernak¹, Ximing J. Yang^1,2, Wei Hsueh³, Jan L. Leestma³, Jennifer Stagl⁴, Stewart Goldman⁴

Canadian Journal of Urology, Vol.14, No.6, pp. 3739-3744, 2007

Abstract Pediatric renal cell carcinoma (RCC) is relatively rare and appears to comprise a group of tumors distinct from RCCs typically seen in adults. Recently described tumors show an association with neuroblastoma or specific chromosomal translocations. Only rarely have other childhood cancers been associated with pediatric RCC. We present two cases of pediatric RCC following treatment of other childhood malignancies not previously described, supratentorial primitive neuroectodermal tumor and acute lymphoblastic leukemia, and review the literature on pediatric RCC. As the RCCs were discovered as incidental radiologic findings, we emphasize the importance of close follow-up (including imaging) More >

Ivar Bleumer¹, Pieter H. M. de Mulder², Peter F. A. Mulders¹

Canadian Journal of Urology, Vol.13, Suppl.2, pp. 57-62, 2006

Abstract Renal cell carcinoma (RCC) presents as localized disease in 54% of the cases. For these patients, surgery is the primary curative treatment. Unfortunately, up to 65% of all patients show recurrent disease. For metastatic RCC non-specific immunotherapy is currently the treatment of choice. Nevertheless, several new modalities, e.g. WX-G250, oncophage and anti-angiogenic compounds like sunitinib and sorafenib are being explored with favorable results. Still, their place in the primary treatment of advanced RCC has yet to be determined. Because of the high percentage of recurrent disease, there is a need to identify these patients with… More >