MAJA MILOSEVIC^1,2, MILOS LAZAREVIC^1,2, BOSKO TOLJIC¹, MILAN PETROVIC², MIROSLAV VUKADINOVIC², ZORAN JEZDIC², BOBAN ANICIC², DRAGO JELOVAC², SVETLANA JOVANOVIC³, JELENA MILASIN^1,*

BIOCELL, Vol.45, No.6, pp. 1543-1550, 2021, DOI:10.32604/biocell.2021.015060 - 01 September 2021

Abstract Specific cell subpopulations identified as cancer stem cells (CSCs) can be found in basal cell carcinoma (BCC). Generally, CSCs have a marked trans-differentiation potential that could potentially be used in differentiation therapies. However, there are no studies regarding BCC CSCs multipotency. The aim of the study was to analyze the characteristic of CSCs of BCC with emphasis on their differentiation potential upon specific induction. Specific staining and cell morphology were used for differentiation confirmation, along with the expression analysis of osteogenic (ALP, BSP, Runx2, OCN, BMP2), chondrogenic (COL1 and COL2A1), adipogenic (PPAR-γ) and neurogenic (Nestin More >

Arun Kumar^1,*, Sivabalan Ambigapathy², Mehedi Masud³, Emad Sami Jaha⁴, Sumit Chakravarty⁵, Kanchan Sengar¹

CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 2967-2981, 2021, DOI:10.32604/cmc.2021.019092 - 24 August 2021

Abstract The article introduces Non-Orthogonal Multiple Access (NOMA) and Filter Bank Multicarrier (FBMC), known as hybrid waveform (NOMA-FBMC), as two of the most deserving contenders for fifth-generation (5G) network. High spectrum access and clampdown of spectrum outflow are unique characteristics of hybrid NOMA-FBMC. We compare the spectral efficiency of Orthogonal Frequency Division Multiplexing (OFDM), FBMC, NOMA, and NOMA-FBMC. It is seen that the hybrid waveform outperforms the existing waveforms. Peak to Average Power Ratio (PAPR) is regarded as a significant issue in multicarrier waveforms. The combination of Selective Mapping-Partial Transmit Sequence (SLM-PTS) is an effective way More >

Mohammed Abd-Elnaby^*, Sameer Alsharif, Hesham Alhumyani, Fahad Alraddady

Intelligent Automation & Soft Computing, Vol.30, No.3, pp. 1033-1048, 2021, DOI:10.32604/iasc.2021.019341 - 20 August 2021

Abstract Non-orthogonal multiple access (NOMA) is one of the promising 5G technologies to improve spectral efficiency massive connectivity and cell-edge throughput. The performance of NOMA systems mainly depends on the efficiency of the subcarrier allocation algorithm. This paper aims to jointly optimize spectral efficiency (SE), outage probability, and fairness among users with respect to the subcarrier allocation for downlink NOMA systems. We propose a low-complexity greedy-based subcarrier allocation algorithm based on the lowest-opportunities user’s first precept. This precept is based on computing the number of opportunities for each user to select a subcarrier with good channel More >

A. Sheryl Oliver¹, T. Jayasankar², K. R. Sekar^3,*, T. Kalavathi Devi⁴, R. Shalini⁵, S. Poojalaxmi⁵, N. G. Viswesh⁵

Intelligent Automation & Soft Computing, Vol.30, No.3, pp. 755-770, 2021, DOI:10.32604/iasc.2021.016242 - 20 August 2021

Abstract Lung cancer is a poorly understood disease. Smokers may develop lung cancer due to the inhalation of carcinogenic substances while smoking, but non-smokers may develop this disease as well. Lung cancer can spread to other parts of the body and this process is called metastasis. Because the lung cancer is difficult to identify in the initial stages. The objective of this work is to reduce the mortality rate of the disease by identifying it at an earlier stage based on the existing symptoms. Artificial intelligence plays active roles in tasks such as entropy extraction through… More >

Jianming Zhao^1,2,3,4, Peng Zeng^1,2,3,4,*, Chunyu Chen^1,2,3,4, Zhiwei Dong⁵, Jongho Han⁶

Intelligent Automation & Soft Computing, Vol.30, No.1, pp. 337-350, 2021, DOI:10.32604/iasc.2021.016966 - 26 July 2021

Abstract As networked control systems continue to be widely used in large-scale industrial productions, industrial cyber-attacks have become an inevitable problem that can cause serious damage to critical infrastructures. In practice, industrial intrusion detection has been widely acknowledged to detect abnormal communication behaviors. However, unlike traditional IT systems, networked control systems have their own communication characteristics due to specific industrial communication protocols. Thus, simple cyber-attack modeling is inadequate and impractical for high-efficiency intrusion detection because the characteristics of network control systems are less considered. Based on the status information and transmission connection in industrial communication data… More >

Merna Gamal¹, Hala M. Abbas², Nour Moustafa^3,*, Elena Sitnikova³, Rowayda A. Sadek¹

CMC-Computers, Materials & Continua, Vol.69, No.2, pp. 1823-1837, 2021, DOI:10.32604/cmc.2021.012877 - 21 July 2021

Abstract Intrusion Detection Systems (IDSs) have a great interest these days to discover complex attack events and protect the critical infrastructures of the Internet of Things (IoT) networks. Existing IDSs based on shallow and deep network architectures demand high computational resources and high volumes of data to establish an adaptive detection engine that discovers new families of attacks from the edge of IoT networks. However, attackers exploit network gateways at the edge using new attacking scenarios (i.e., zero-day attacks), such as ransomware and Distributed Denial of Service (DDoS) attacks. This paper proposes new IDS based on… More >

ISIDORA PETROVIC¹, MILENA MILIVOJEVIC¹, ANA ARSENIJEVIC², ANDRIJANA LAZIC¹, NATASA KOVACEVIC GRUJICIC¹, MARIJA SCHWIRTLICH¹, JELENA POPOVIC³, MILENA STEVANOVIC^1,4,5,*

BIOCELL, Vol.45, No.5, pp. 1355-1367, 2021, DOI:10.32604/biocell.2021.015817 - 12 July 2021

Abstract Genetic and molecular heterogeneity, together with intrinsic and acquired resistance to therapy, represent the major obstacles to the successful treatment of different types of breast carcinoma. Increasing evidence demonstrates that SOX transcription factors in breast carcinomas could act both as oncogenes and tumor suppressors and have been associated with tumor stage and grade, poor prognosis, and therapy resistance. Both SOX2 and SOX18 overexpression has been correlated with poor prognosis in breast carcinomas, and these genes are recognized as potential antitumor targets. Our aim was to evaluate the effect of retinoic acid (RA), a well-known cyto-differentiating agent,… More >

TING LAN, SHENG QIN, XIAOJIN GONG, PING ZHENG, JIAXIN YAN, YANG LIU^*

BIOCELL, Vol.45, No.5, pp. 1313-1319, 2021, DOI:10.32604/biocell.2021.015923 - 12 July 2021

Abstract Invasive stratified mucin-producing carcinoma (ISMC) is a recently described histologic variant of high-risk human papillomavirus (HPV)-associated endocervical adenocarcinoma, as the putative invasive counterpart of the stratified mucin-producing intraepithelial lesion (SMILE). ISMC can display variable architectural patterns and usually coexists with other more conventional types of HPV-associated carcinomas, which makes diagnosis and differential diagnosis of ISMC is difficult for pathologists. Moreover, the prognosis of ISMC is still controversial. We analyzed 6 ISMCs with detailed pathological and clinical information. Intraepithelial lesion, including 1 high-grade squamous intraepithelial lesion and 1 SMILE, was found. Various architectures were observed (including… More >

Milica Karadzic Kocica¹, Hristina Ugrinovic¹, Dejan Lazovic², Nemanja Karamarkovic², Milos Grujic², Borivoje Lukic³, Oliver Radmili³, Vladimir Cvetic³, Mladen Kocica^2,*

Congenital Heart Disease, Vol.16, No.6, pp. 647-653, 2021, DOI:10.32604/CHD.2021.016923 - 08 July 2021

Abstract A single coronary artery is a very rare condition, commonly associated with other congenital anomalies. It could be generally considered as neither benign nor malignant form of congenital coronary artery anomalies since its pathophysiological and clinical implications grossly depend on different anatomical patterns defined by the site of origin and distribution of the branches. By presenting the patient who underwent successful coronary artery bypass grafting and aortic valve replacement surgery in a presence of isolated single coronary artery, we intend to emphasize natural and procedural risks and distinguish casual from causal in this extremely rare More >

Ruikun Li^1,*, Yun Li², Wen He^1,3, Lirong Chen¹, Jianchao Luo¹

CMES-Computer Modeling in Engineering & Sciences, Vol.128, No.1, pp. 381-398, 2021, DOI:10.32604/cmes.2021.016264 - 28 June 2021

Abstract Anomaly detection is an important method for intrusion detection. In recent years, unsupervised methods have been widely researched because they do not require labeling. For example, a nonlinear autoencoder can use reconstruction errors to attain the discrimination threshold. This method is not effective when the model complexity is high or the data contains noise. The method for detecting the density of compressed features in a hidden layer can be used to reduce the influence of noise on the selection of the threshold because the density of abnormal data in hidden layers is smaller than normal… More >