Yangkyun kim¹, Sungcho Kim², Jongwook Choi², Jeong Soo Kim²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.11, No.4, pp. 123-124, 2009, DOI:10.3970/icces.2009.011.123

Abstract This paper analyzes computationally the flow field for the full geometry model of a commercial passenger airplane, Boeing747-400. The geometric dimension of an airplane was acquired by means of the reverse engineering technique adopting the photo scanning measurement. The steady three-dimensional viscous compressible flow field was calculated when the airplane cruises under side flow. The basic computational conditions were considered as the same to those of Boeing 747-400's cruising state, i.e., the atmospheric condition at 13 km above the sea level and Mach number of 0.85. The boundary conditions are the same that the freestream… More >

Jack Barkin

Canadian Journal of Urology, Vol.15, Suppl.4, pp. 21-30, 2008

Abstract Benign prostatic hyperplasia (BPH) is one of the commonest causes of lower urinary tract symptoms (LUTS) in men over age 50. Fifty percent of men over age 50 will require some type of management for BPH/LUTS symptoms. Until about 15 years ago, the most common management for BPH was a transurethral resection of the prostate (TURP) operation. Initially, once a diagnosis of BPH has been made, most men are treated medically. One must fi rst rule out other serious causes of these symptoms, such as prostate cancer, bladder cancer, and other obstructions. For men with… More >

Jack Barkin

Canadian Journal of Urology, Vol.15, No.6, pp. 4353-4358, 2008

Abstract Symptomatic benign prostatic hyperplasia (BPH) is one of the commonest causes of men presenting with lower urinary tract symptoms (LUTS). We can fi nd this in 50% of men over the age of fi fty. If BPH is not treated, then one can expect that the disease will progress in a signifi cant number of individuals. What we need to do is try to predict, based on certain baseline parameters such as International Prostate Score (IPSS), prostate volume, prostate-specifi c antigen (PSA) and the degree of bother, those men to whom we should offer therapy. More >

Jeffrey W. Nix, Culley C. Carson

Canadian Journal of Urology, Vol.14, Suppl.6, pp. 53-57, 2007

Abstract Benign prostatic hyperplasia (BPH) is a common condition of the aging male. The bladder outlet obstruction caused by this condition occurs despite variations in prostate size. Symptoms of BPH include the irritative and obstructive voiding symptoms termed lower urinary tract symptoms (LUTS). While transurethral surgery has long been the gold standard for treatment of LUTS, medical treatment has emerged as the first line of treatment for those men who fail expectant or watchful waiting treatment. Medical options include: alpha blockers, 5α-reductase inhibitors and newly identified PDE 5 inhibitors, drugs for erectile dysfunction that have a… More >

E. Shaik^∗, K.A. Hoffmann^∗, J-F. Dietiker^∗

Molecular & Cellular Biomechanics, Vol.4, No.1, pp. 41-54, 2007, DOI:10.3970/mcb.2007.004.041

Abstract A potential interaction between the local hemodynamics and the artery wall response has been suggested for vascular graft failure by intimal hyperplasia (IH). Among the various hemodynamic factors, wall shear stress has been implicated as the primary factor responsible for the development of IH. In order to explore the role of hemodynamics in the formation of IH in end-to-side anastomosis, computational fluid dynamics is employed. To validate the numerical simulations, comparisons with existing experimental data are performed for both steady and pulsatile flows. Generally, good agreement is observed with the velocity profiles whereas some discrepancies… More >

Hanna Bialkowska-Hobrzanska, David K. Driman, Robert Fletcher, Vimla Harry, Hassan Razvi

Canadian Journal of Urology, Vol.13, No.1, pp. 2967-2974, 2006

Abstract Background: The variable clinical behavior displayed by prostate cancer (PCa) warrants investigation of potential PCa-specific biomarkers that could identify more aggressive tumor types and therefore provide prognostic value. Upregulation of expression of human telomerase reverse transcriptase (hTERT), Survivin, DD3 and PCGEM1 mRNAs in PCa lesions has recently been described. The purpose of this study was to evaluate the clinical value of detection of overexpression of these biomarkers in the diagnosis and prognosis of PCa.
Material and methods: Archival formalin-fixed, paraffin-embedded (FFPE) prostatectomy tissue from 26 patients with PCa (Gleason score 3-9, mean 7) and 14 patients with… More >

François Meyer, Bernard Têtu, Isabelle Bairati, Louis Lacombe, Yves Fradet

Canadian Journal of Urology, Vol.13, No.5, pp. 3255-3260, 2006

Abstract Purpose: Prostatic intraepithelial neoplasia (PIN) is considered as a precursor lesion for adenocarcinoma of the prostate. Most data supporting this relationship comes from the short-term follow-up of patients with repeated biopsies. We report a study in which patients were followed-up for 11 years to assess the relationships between the presence of high grade PIN, low grade PIN, and atypical adenomatous hyperplasia (AAH) and the subsequent occurrence of prostate cancer.
Materials and methods: For 601 men treated by TURP in 1990-1993, prostate specimens were reviewed to assess the presence of high grade PIN, low grade PIN, and AAH.… More >

H. McDonald, M. Hux, M. Brisson, L. Bernard, J.C. Nickel

Canadian Journal of Urology, Vol.12, No.1, pp. 2508-2510, 2005

Abstract This article has no abstract. More >

J. Curtis Nickel¹, Sender Herschorn², Jacques Corcos², Bryan Donnelly¹, Doug Drover², Mostafa Elhilali¹, Larry Goldenberg¹, John Grantmyre², Bruno Laroche², Richard Norman¹, Bruce Piercy¹, Karen Psooy², Gary Steinhoff¹, John Trachtenberg¹, Fred Saad¹, Simon Tanguay¹

Canadian Journal of Urology, Vol.12, No.3, pp. 2677-2683, 2005

Abstract Objective: To develop the first Canadian guidelines for the management of lower urinary tract symptoms in men with benign prostatic hyperplasia (BPH).
Methods: These guidelines, developed under a mandate provided by the Canadian Urological Association (CUA), were a collaborative effort between the CUA guidelines committee and the Canadian Prostate Health Council. BPH guidelines developed by the American Urological Association, the European Association of Urology, the World Health Organization International Consultation on BPH, and similar committees from Germany, Sweden and Australia were reviewed. The committee further reviewed a systematic literature search, updated to May 2004, and systematically derived… More >

Fred Saad¹, J. Curtis Nickel², Luc Valiquette¹, Richard Casey³, Irwin Kuzmarov⁴, Mostafa Elhilali⁵

Canadian Journal of Urology, Vol.12, No.4, pp. 2745-2754, 2005

Abstract Introduction and objectives: A novel slow release formulation of alfuzosin should improve compliance by reducing dosing to one 10 mg tablet per day. The current study examined efficacy, at 9 days and 3 months, and safety of this formulation of alfuzosin in BPH patients.
Methods: ALF-X was a 3-month, non-comparative, observational study of 353 BPH patients from 39 Canadian Urology centres.
Results: At baseline (BL), mean age was 63.1±9.01 years, 92.6% of patients were Caucasian, 3.4% had a history of acute urinary retention, mean duration of the micturition disorder was 48.6±54.15 months, and mean PSA was 3.3±6.65 ng/mL.… More >