TARYN E. SYMON¹, RAMÓN GAXIOLA-ROBLES^1,2, CLAUDIA J. HERNÁNDEZ-CAMACHO³, TANIA ZENTENO-SAVÍN^1,*

BIOCELL, Vol.45, No.6, pp. 1621-1630, 2021, DOI:10.32604/biocell.2021.016302 - 01 September 2021

Abstract Marine mammals undergo cycles of tissue ischemia and reperfusion during the dive response. Reperfusion injury can result in oxidative tissue damage and the activation of a pro-inflammatory immune response. The risk of oxidative damage is reduced by antioxidants. Our hypothesis is that the reported higher antioxidant defenses within marine mammal tissues provide additional protection in situations that produce oxidative stress, like inflammation, in comparison to terrestrial mammal tissues. Leukocytes were isolated from the whole blood of Pacific bottlenose dolphins (Tursiops truncatus gilli) and humans (Homo sapiens) and were exposed to lipopolysaccharides (LPS, 10 µg/mL) in vitro to simulate… More >

Mengyuan Dong^#, Rong Sun^#, Qianhui Yang, Lantian Zhang, Yangying Yong, Yunxia Fang, Xian Zhang, Xiaoqin Zhang^*, Dawei Xue^*

Phyton-International Journal of Experimental Botany, Vol.90, No.6, pp. 1589-1598, 2021, DOI:10.32604/phyton.2021.017465 - 28 June 2021

Abstract In recent years, zinc oxide nanoparticles (ZnO NPs) have been widely used as zinc fertilizers and pesticides. The use of ZnO NPs in this way can provide benefits to humans, but also has potential risks. ZnO NPs inevitably enter the environment during their production and use, which affects the ecological environment and crop growth. In order to investigate the phenotype, physiology, and gene expression of barley (Hordeum vulgare L.) seedlings under ZnO NPs stress, the barely cultivars ZJU3 (P21), Golden Promise (GP) and L23 were chosen for study. Different ZnO NPs concentrations were applied to compare… More >

CHUNJIAO LIU^1,2, QINHONG KONG^1,2, FENG PAN^1,2, SHAN JIANG^1,2, LINGJIE MENG^1,2, GAI HUANG^1,2, LIDAN LU^1,2, SANHUA LI^1,2,*, YUN LIU^1,2,3,*

BIOCELL, Vol.45, No.4, pp. 943-951, 2021, DOI:10.32604/biocell.2021.015836 - 22 April 2021

Abstract Traditional Chinese medicine (TCM) has been increasingly applied in both preventing and treating a variety of cancers in the last decades, attributing to its fewer side effects as compared with chemotherapy drugs. Hellebrigenin, a component of Chanpi from the skin of Bufo bufogargarizans Cantor or Duttaphrynus melanostictus has been reported to have an obvious anti-cancer activity on various cancers. However, the effect and mechanism of hellebrigenin on colorectal cancers were still unknown. Herein, the present study demonstrated hellebrigenin significantly reduced viability and triggered apoptosis via the intrinsic pathway in colorectal cancer cell lines HCT116 and HT29 in More >

CHUNKUN FAN, YONGPENG ZHANG, CHUNBAO YANG, YAWEI TANG, JI QU, BU JIE, DEJI QUZHEN, LIYUN GAO^*

BIOCELL, Vol.45, No.4, pp. 1121-1135, 2021, DOI:10.32604/biocell.2021.014336 - 22 April 2021

Abstract Salinity is a serious challenge for agriculture production by limiting the arable land. Rice is a major staple food crop but very sensitive to salt stress. In this study, we used Arabidopsis for the functional characterization of a rice F-box gene LOC_Os04g48270 (OsPP12-A13) under salinity stress. OsPP12-A13 is a nuclear-localized protein that is strongly upregulated under salinity stress in rice and showed the highest expression in the stem, followed by roots and leaves. Two types of transgenic lines for OsPP12-A13 were generated, including constitutive tissue over-expression using the CaMV35S promoter and phloem specific over-expression using the pSUC2 promoter.… More >

ZIXUAN WANG^1,#, HONGMEI PENG^2,#, WEI SHI^4,#, LU GAN¹, LIPING ZHONG¹, JIAN HE¹, LINLIN XIE¹, PAN WU¹, YONGXIANG ZHAO¹, ZHIMING DENG^3,*, HONGLIANG TANG⁴, YONG HUANG^1,3,*

BIOCELL, Vol.45, No.3, pp. 489-500, 2021, DOI:10.32604/biocell.2021.014439 - 03 March 2021

Abstract Although great achievements have been made in the past decades in medicine, cancer remains a worldwide public health issue. Surgery is usually accompanied by shortcomings such as residual lesions and poor treatment effects, and the successive appearance of other treatment methods, such as radiotherapy and chemotherapy, has not changed the postoperative recurrence rate, toxicity, and side effects. However, the advent of photodynamic therapy has greatly improved this situation. Photodynamic therapy is an emerging tumor diagnosis and treatment technology with good application prospects, photodynamic therapy uses a specific wavelength of light to excite a photosensitizer to More >

Abdul Awal Chowdhury Masud¹, Md. Fazlul Karim¹, M. H. M. Borhannuddin Bhuyan², Jubayer Al Mahmud³, Kamrun Nahar⁴, Masayuki Fujita⁵, Mirza Hasanuzzaman^1,*

Phyton-International Journal of Experimental Botany, Vol.90, No.2, pp. 353-372, 2021, DOI:10.32604/phyton.2021.013259 - 07 February 2021

Abstract Drought is the most common form of abiotic stress that reduces plant growth and productivity. It causes plant injuries through elevated production of reactive oxygen species (ROS). Potassium (K) is a vital plant nutrient that notably ameliorates the detrimental effect of drought stress in the plant. A pot experiment was conducted at the Laboratory of Plant Stress Responses, Faculty of Agriculture, Kagawa University, Japan, under controlled environment of green house to explore the role of K in mitigating drought severity in wheat (Triticum asevitum L.) seedlings. Three days after germination, seedlings were exposed to three water… More >

Hailin Shi^#, Shiwei Sun^#, Xiaohong Liu, Jiahe Fan, Jin Wang, Ke Zhao, Wei Wang^*

Phyton-International Journal of Experimental Botany, Vol.90, No.1, pp. 159-170, 2021, DOI:10.32604/phyton.2020.011620 - 20 November 2020

Abstract Allelopathic plants are important resources for the discovery of bioherbicides. Rosebay willowherb [Chamaenerion angustifolium (L.) Scop. syn. Epilobium angustifolium L.] widely distributes in Western Asia, Europe, and North America, and behaves as a dominant species within the community due to the production of substances that restrict growth of other plants. This study aims at investigating the allelopathic potential of rosebay willowherb by evaluation of the effects of aqueous extracts from different parts on seed germination and seedling growth in lettuce (Lactuca sativa L.), as well as measuring the accumulation of reactive oxygen species and structural analysis of root… More >

Qie Guo^*, Xiao Li^*, Meng-Na Cui^*, Jia-Lin Sun^*, Hong-Yan Ji^*, Bei-Bei Ni^*, Mei-Xing Yan^†

Oncology Research, Vol.28, No.5, pp. 533-540, 2020, DOI:10.3727/096504020X15919605976853

Abstract Cancer is one of the most serious diseases that are harmful to human health. Systemic chemotherapy is an optimal therapeutic strategy for the treatment of cancer, but great difficulty has been encountered in its administration in the form of multidrug resistance (MDR). As an enzyme on the outer cell surface, CD13 is documented to be involved in the MDR development of tumor cells. In this review, we will focus on the role of CD13 in MDR generation based on the current evidence. More >

Mahmuda Binte Monsur¹, Nasrin Akter Ivy¹, M. Moynul Haque², Mirza Hasanuzzaman³, Ayman EL Sabagh^4,5,*, Md. Motiar Rohman^6,*

Phyton-International Journal of Experimental Botany, Vol.89, No.3, pp. 497-517, 2020, DOI:10.32604/phyton.2020.09144 - 22 June 2020

Abstract The research was conducted to investigate comparative oxidative damage including probable protective roles of antioxidant and glyoxalase systems in rice (Oryza sativa L.) seedlings under salinity stress. Seedlings of two rice genotypes: Pokkali (tolerant) and BRRI dhan28 (sensitive) were subjected to 8 dSm⁻¹ salinity stress for seven days in a hydroponic system. We observed significant variation between Pokkali and BRRI dhan28 in phenotypic, biochemical and molecular level under salinity stress. Carotenoid content, ion homeostasis, antioxidant enzymes, ascorbate and glutathione redox system and proline accumulation may help Pokkali to develop defense system during salinity stress. However, the activity More >

Zhenzhen SHI, Jiaxin CAO, Hailong PANG, Lingyun JIA, Kun SUN, Hanqing FENG^*

BIOCELL, Vol.44, No.1, pp. 89-99, 2020, DOI:10.32604/biocell.2020.08059 - 01 March 2020

Abstract Cadmium (Cd) is one of the most widespread and toxic heavy metals to plants. Extracellular ATP (exATP) is thought to be an extracellular effector in regulating the physiological responses of plant cells to environmental stresses. However, the function of exATP in Cd-stressed plant cells is much unknown. The present work showed that treating tobacco (Nicotiana tabacum L. cv. Bright Yellow-2) cell-suspension cultures with exogenous CdCl₂ reduced the cell viability, exATP level, and Mg content. However, the production of reactive oxygen species (ROS), Cd content, and electrolyte leakage of the cells were enhanced by exogenous CdCl₂. When the… More >