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  • Open Access

    ARTICLE

    Risk factors for postoperative Clostridium difficile infection after radical cystectomy for bladder cancer: a NSQIP database analysis

    Canadian Journal of Urology, Vol.29, No.3, pp. 11170-11174, 2022

    Abstract Introduction: Patients undergoing cystectomy for bladder cancer are at an increased risk for Clostridium difficile infection (CDI) due to prolonged antibiotics and underlying comorbidities. We aim to evaluate CDI risk factors in cystectomy patients.
    Materials and methods: Utilizing National Surgical Quality Improvement Program (NSQIP), patients undergoing cystectomy with diagnosis of bladder cancer between 2015-2017 were included. Baseline demographics including age, sex, comorbidities, and preoperative labs were collected. Univariate and multivariable logistic regression were used to evaluate risk factors for and complications of CDI during the index hospitalization.
    Results: There were a total of 6,432 patients included in the… More >

  • Open Access

    REVIEW

    Epidemiology of Breast Cancer

    Chao Shang, Dongkui Xu*

    Oncologie, Vol.24, No.4, pp. 649-663, 2022, DOI:10.32604/oncologie.2022.027640 - 31 December 2022

    Abstract All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence… More >

  • Open Access

    ARTICLE

    Incidence and Related Risk Factors of Junctional Ectopic Tachycardia in Infants after Cardiac Surgery for Congenital Heart Disease

    Jae Hee Seol1,4,#, Se Yong Jung1,#, Jae Young Choi1, Han Ki Park2, Young Hwan Park2, Nam Kyun Kim1,3,*

    Congenital Heart Disease, Vol.17, No.5, pp. 569-578, 2022, DOI:10.32604/chd.2022.018436 - 06 September 2022

    Abstract Objective: Junctional ectopic tachycardia is common after cardiac surgery for congenital heart disease. However, its incidence and related risk factors in infants after cardiac surgery are not well known. The objective of this study was to determine the overall incidence and related risk factors for junctional ectopic tachycardia in neonates and infants. Methods: We enrolled a total of 271 patients aged <1 year who underwent open cardiac surgery at Severance Cardiovascular Hospital from January 2018 to December 2020. Exclusion criteria were immediate postoperative mortality, other arrhythmias detected in the perioperative period, and prematurity. Result: The overall incidence of… More >

  • Open Access

    ARTICLE

    Risk Factors and Gender Differences for Depression in Chilean Older Adults: A Cross-Sectional Analysis from the National Health Survey 2016–2017

    Gabriela Nazar1,2,*, Carlos-María Alcover3, Yeny Concha-Cisternas4,5, Igor Cigarroa5, Ximena Díaz-Martínez6, Mariela Gatica-Saavedra7, Fabián Lanuza8,9, Ana María Leiva-Ordónez10, María Adela Martínez-Sanguinetti11, Miquel Martorell2,12, Fanny Petermann-Rocha13,14, Claudia Troncoso-Pantoja15, Carlos Celis-Morales16

    International Journal of Mental Health Promotion, Vol.24, No.5, pp. 679-697, 2022, DOI:10.32604/ijmhp.2022.020105 - 27 July 2022

    Abstract Depressive disorders are recognized as one of the most common mental health conditions across different age groups. However, the risk factors associated with depression among older people from low-and middle-income countries remains unclear. This study aims to identify socio-demographic, health and psychosocial-related factors associated with depression in Chilean older adults. A cross-sectional study was carried out in a representative sample of 1,765 adults aged ≥60 years participants from the Chilean National Health Survey 2016–2017. Depression was assessed with the Composite International Diagnostic Interview (CIDI-SF). Associations between the exposure variables and depression were investigated using Poisson… More >

  • Open Access

    ARTICLE

    Dynamic Voting Classifier for Risk Identification in Supply Chain 4.0

    Abdullah Ali Salamai1, El-Sayed M. El-kenawy2, Ibrahim Abdelhameed3,*

    CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 3749-3766, 2021, DOI:10.32604/cmc.2021.018179 - 24 August 2021

    Abstract Supply chain 4.0 refers to the fourth industrial revolution’s supply chain management systems, which integrate the supply chain’s manufacturing operations, information technology, and telecommunication processes. Although supply chain 4.0 aims to improve supply chains’ production systems and profitability, it is subject to different operational and disruptive risks. Operational risks are a big challenge in the cycle of supply chain 4.0 for controlling the demand and supply operations to produce and deliver products across IT systems. This paper proposes a voting classifier to identify the operational risks in the supply chain 4.0 based on a Sine… More >

  • Open Access

    ARTICLE

    Relationship between PON-1 enzymatic activity and risk factors for pesticide poisoning in farmers from the Cienega, Jalisco, Mexico

    HAZAEL RAMIRO CEJA-GALVEZ1, ERANDIS DHENI TORRES-SÁNCHEZ1, JUAN HERIBERTO TORRES-JASSO2, EMMANUEL REYESURIBE1, JOEL SALAZAR-FLORES1,*

    BIOCELL, Vol.45, No.5, pp. 1241-1250, 2021, DOI:10.32604/biocell.2021.015771 - 12 July 2021

    Abstract Paraoxonase-1 (PON-1) is an enzyme that hydrolyzes organophosphate pesticides. The presence of polymorphisms in PON-1 (L55M and Q192R) decreases its enzyme activity and increases the risk of central nervous system (CNS) toxicity in occupationally exposed farmers, leading to chronic degenerative diseases and death. We studied 103 farmers in the region of Cienega Jalisco, Mexico, which were exposed mainly to organophosphate pesticides. We used serum and plasma samples to assay PON-1 activity and perform polymorphism analysis (L55M and Q192R) using qPCR and TaqMan probes, respectively. For both polymorphisms, there was high percentage of heterozygosity (55 LL… More >

  • Open Access

    ARTICLE

    Hypertension and Heart Failure as Predictors of Mortality in an Adult Congenital Heart Defect Population

    Cheryl Raskind-Hood1,*, Kashaine A. Gray2,3, Jayne Morgan3, Wendy M. Book4,*

    Congenital Heart Disease, Vol.16, No.4, pp. 333-355, 2021, DOI:10.32604/CHD.2021.014384 - 19 April 2021

    Abstract Early intervention to prevent premature mortality is vital for adults with congenital heart defects (CHD). Anatomic complexity and comorbid conditions are thought to contribute to CHD mortality. Since hypertension (HTN) and heart failure (HF) are the comorbid conditions among the most prevalent causes of death in the United States, and commonly accompany CHD, it is crucial to evaluate whether they are reliable predictors of mortality for adults with CHD (ACHD) independent of anatomic CHD complexity. A retrospective cross-sectional analysis of ACHD, aged 18–64, with concomitant HTN and/or HF and at least one health care encounter… More >

  • Open Access

    ARTICLE

    Acquired Coronary Artery Disease in Patients with Congenital Heart Disease: Issues in Diagnosis and Management

    Sotiria C. Apostolopoulou1,*, Stella Brili2, Eftihia Sbarouni3, Dimitris Tousoulis2, Konstantinos Toutouzas2

    Congenital Heart Disease, Vol.15, No.5, pp. 369-375, 2020, DOI:10.32604/CHD.2020.012092 - 23 September 2020

    Abstract Objective: Acquired coronary artery disease, initially thought to rarely affect survivors of congenital heart disease, is increasingly recognized in this population, as these patients grow in age and numbers in the recent era. This study reports our experience with coronary artery disease in adults with congenital heart disease and discusses treatment issues and the existing literature. Methods: Retrospective review of all charts of adults with congenital heart disease and acquired coronary artery disease was performed. Patients’ clinical characteristics, diagnosis, risk factors, noninvasive and invasive imaging and management data were recorded. Results: Coronary artery disease was diagnosed at… More >

  • Open Access

    ARTICLE

    Atrial Septal Defect in Children: The Incidence and Risk Factors for Diagnosis

    Gustaf Tanghöj1,*, Anna Lindam2, Petru Liuba3,4, Gunnar Sjöberg5, Estelle Naumburg1

    Congenital Heart Disease, Vol.15, No.5, pp. 287-299, 2020, DOI:10.32604/CHD.2020.011977 - 23 September 2020

    Abstract Objective: Secundum atrial septal defect (ASD II) is a common congenital heart defect, and interatrial communications among preterm children is even more common. The objective of this study was to calculate the incidence of ASD II in children, with assessment to gestational age at birth. Further, to assess maternal, prenatal and postnatal risk factors associated with ASD II among children of different gestational age at birth. Design: This national registry based retrospective incidence study was supplemented with a national case-control study, using the Swedish Register of Congenial Heart Disease, Swedish Medical Birth Register and Statistics Sweden.… More >

  • Open Access

    ARTICLE

    Incidence, Risk Factors, and Outcomes of Hyperferritinemia after Pediatric Cardiac Surgery with Cardiopulmonary Bypass: A Retrospective Study

    Shengwen Guo, Yuanyuan Tong, Liting Bai, Peiyao Zhang, Xin Duan*, Jinping Liu*

    Congenital Heart Disease, Vol.15, No.5, pp. 275-285, 2020, DOI:10.32604/CHD.2020.011894 - 23 September 2020

    Abstract Objective: Serum ferritin has been identified as a prognostic marker in patients with a variety of diseases. In the present study we aim to determine the prevalence of risk factors and outcomes for hyperferritinemia in children undergoing cardiac surgery with cardiopulmonary bypass for congenital heart defects. Methods: The serum ferritin levels of 457 children between the ages of twentyeight days and three years undergoing cardiopulmonary bypass surgery between June 1, 2017 and June 1, 2018 were analyzed. The prevalence of early postoperative hyperferritinemia was investigated; hyperferritinemia was defined as a ferritin level ≥250 ng/ml. Multivariable regression… More >

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