LORIS RIZZELLO^1,2,3, VALERIA DE MATTEIS^4,*

BIOCELL, Vol.46, No.11, pp. 2369-2380, 2022, DOI:10.32604/biocell.2022.021059

Abstract The SARS-CoV-2 outbreaks highlighted the need for effective, reliable, fast, easy-to-do and cheap diagnostics procedures. We pragmatically experienced that an early positive-case detection, inevitably coupled with a mass vaccination campaign, is a milestone to control the COVID-19 pandemic. Gold nanoparticles (AuNPs) can indeed play a crucial role in this context, as their physicochemical, optics and electronics properties are being extensively used in photothermal therapy (PTT), radiation therapy (RT), drug delivery and diagnostic. AuNPs can be synthesized by several approaches to obtain different sizes and shapes that can be easily functionalized with many kinds of molecules such as antibodies, proteins, probes,… More >

Fawaz Alsolami¹, Abdullah Saad Al-Malaise Alghamdi², Asif Irshad Khan^1,*, Yoosef B. Abushark¹, Abdulmohsen Almalawi¹, Farrukh Saleem², Alka Agrawal³, Rajeev Kumar⁴, Raees Ahmad Khan³

CMC-Computers, Materials & Continua, Vol.73, No.2, pp. 2591-2618, 2022, DOI:10.32604/cmc.2022.025703

Abstract The COVID-19 pandemic has triggered a global humanitarian disaster that has never been seen before. Medical experts, on the other hand, are undecided on the most valuable treatments of therapy because people ill with this infection exhibit a wide range of illness indications at different phases of infection. Further, this project aims to undertake an experimental investigation to determine which treatments for COVID-19 disease is the most effective and preferable. The research analysis is based on vast data gathered from professionals and research journals, making this study a comprehensive reference. To solve this challenging task, the researchers used the HF… More >

Hirdayesh Anuragi¹, Rajesh Kumar Singhal², Yashfa Tanveer³, Humaira Yasmin³, Ambati Srijan⁴, Alka Bharati¹, Lal Chand⁵, Sukumar Taria¹, Kunasekaran Rajarajan¹, Asha Ram¹, Arun Kumar Handa¹, Ayyanadar Arunachalam¹, Khalid Rehman Hakeem^6,7,8,*, Deniz Özbilici⁹, Ayman EL Sabagh^10,11,*

Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 1831-1858, 2022, DOI:10.32604/phyton.2022.020540

Abstract A severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led novel coronavirus disease (COVID-19) outbreak spread through China has become the biggest global public health challenge today. The virus upon several mutations has led to the resurgence of more infectious and lethal variants infecting over 298 million people with more than 5.46 million deaths worldwide by the end of December, 2021. Though vaccines are available, various preventive measures particularly a high body immunity is still extremely important which determines the likelihood of disease severity and subsequent recovery in the current and future pandemics. This review acknowledges the potentiality of miraculous Moringa oleifera… More >

DOMENICO MARIA CARRETTA^1,§, MARINA DI DOMENICO^2,§, ROBERTO LOVERO³, ROBERTO ARRIGONI⁴, ANGELIKA ELZBIETA WEGIERSKA⁵, MARIAROSARIA BOCCELLINO^2,*, ANDREA BALLINI^2,6,*, IOANNIS ALEXANDROS CHARITOS^7,#, LUIGI SANTACROCE^5,#

BIOCELL, Vol.46, No.8, pp. 1779-1788, 2022, DOI:10.32604/biocell.2022.020009

Abstract The existence of an inflammatory process in the heart muscle, related to a progressive worsening of myocardial function, different etiopathogenetic mechanisms concur and often overlap, thus making the diagnosis and the therapeutic approach complex. As the COVID-19 pandemic progresses, the effects of the disease on the organ systems and in particular on the cardiovascular system are becoming more and more profound. Cardiac involvement is a well-known event with a high percentage of findings in the heart’s magnetic field, even in asymptomatic areas. There are numerous uncertainties regarding their evolution, in the long and short term, due not only to a… More >

MOHAMED SALEM^1,2, MOHAMMAD EL-METWALLY³, WESAMELDIN SABER^4,*, SALLY NEGM^5,6, ATTALLA EL-KOTT^7.8, YASSER MAZROUA^9,10, ABEER MAKHLOUF¹¹, MAHMOUD MOUSTAFA^7,12

BIOCELL, Vol.46, No.8, pp. 1979-1988, 2022, DOI:10.32604/biocell.2022.019301

Abstract Profound inspection of the life forms on the earth teaches how to be the complexity of interrelationships among the various systems. Because of the emergence of novel viruses all the time and the inadequate of vaccines and antivirals, viral contagions are amongst the most causative diseases affecting people worldwide. Fungi exemplify a massive source of bioactive molecules as, many fungal secondary metabolities like Oxoglyantrypine, Carneic acid F, Scedapin C, Asteltoxin E, Phomanolide, Norquinadoline A and Quinadoline B have antiviral activity. This review deals with how secondary metabolites of fungi can help in the war against viruses in general and especially… More >

Ankur Dumka¹, Parag Verma², Rajesh Singh³, Anuj Bhardwaj⁴, Khalid Alsubhi⁵, Divya Anand^6,7,*, Irene Delgado Noya^7,8, Silvia Aparicio Obregon^7,9

CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 4453-4466, 2022, DOI:10.32604/cmc.2022.023974

Abstract In December 2019, a group of people in Wuhan city of Hubei province of China were found to be affected by an infection called dark etiology pneumonia. The outbreak of this pneumonia infection was declared a deadly disease by the China Center for Disease Control and Prevention on January 9, 2020, named Novel Coronavirus 2019 (nCoV-2019). This nCoV-2019 is now known as COVID-19. There is a big list of infections of this coronavirus which is present in the form of a big family. This virus can cause several diseases that usually develop with a serious problem. According to the World… More >

FEI CHEN^1,*, CHUN LUAN¹, ZICHUN WEI¹, DECHEN CAI¹, ZHIWEN CUI¹, YUYANG LI¹, HAO WU², XIAOXIA ZHANG¹, XIAOLI WU²

BIOCELL, Vol.46, No.6, pp. 1425-1433, 2022, DOI:10.32604/biocell.2022.019868

Abstract The coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed a potential threat to infant health. The World Health Organization recommended that the benefits of breastfeeding far outweigh the potential risk of transmission, but there is no denying that the current evidence is insufficient. Moreover, although the COVID-19 mRNA vaccine has played an effective role in protection against infection, individuals have increasing concerns about the safety of breastfeeding after vaccination, and which have caused some breastfeeding women to postpone vaccination or stop breastfeeding early. Thus, in this review, we provide an in-depth… More >

Nada M. Mostafa^1,5,#, Muhammad I. Ismail^2,#, Amr M. El-Araby³, Dina M. Bahgat¹, Ahmed M. Elissawy^1,5, Ahmed M. Mostafa⁴, Omayma A. Eldahshan^1,5,*, Abdel Nasser B. Singab^1,5,*

Phyton-International Journal of Experimental Botany, Vol.91, No.5, pp. 1089-1104, 2022, DOI:10.32604/phyton.2022.018239

Abstract Coronaviruses caused an outbreak pandemic disease characterized by a severe acute respiratory distress syndrome leading to the infection of more than 200 million patients and the death of more than 4 million individuals. The primary treatment is either supportive or symptomatic. Natural products have an important role in the development of various drugs. Thus, screening of natural compounds with reported antiviral activities can lead to the discovery of potential inhibitory entities against coronaviruses. In the current study, an in-silico molecular docking experiment was conducted on the effects of some of these natural antiviral phytoconstituents, (e.g., procyanidin B2, theaflavin, quercetin, ellagic… More >

Meshrif Alruily¹, Mohamed Ezz^1,2, Ayman Mohamed Mostafa^1,3, Nacim Yanes^1,4, Mostafa Abbas⁵, Yasser El-Manzalawy^5,*

CMC-Computers, Materials & Continua, Vol.71, No.1, pp. 1751-1768, 2022, DOI:10.32604/cmc.2022.020714

Abstract Accurate forecasting of emerging infectious diseases can guide public health officials in making appropriate decisions related to the allocation of public health resources. Due to the exponential spread of the COVID-19 infection worldwide, several computational models for forecasting the transmission and mortality rates of COVID-19 have been proposed in the literature. To accelerate scientific and public health insights into the spread and impact of COVID-19, Google released the Google COVID-19 search trends symptoms open-access dataset. Our objective is to develop 7 and 14-day-ahead forecasting models of COVID-19 transmission and mortality in the US using the Google search trends for COVID-19… More >

Mohammed Baz¹, Sabita Khatri², Abdullah Baz³, Hosam Alhakami⁴, Alka Agrawal², Raees Ahmad Khan^2,*

Computer Systems Science and Engineering, Vol.40, No.2, pp. 691-702, 2022, DOI:10.32604/csse.2022.019079

Abstract The rapid emergence of novel virus named SARS-CoV2 and unchecked dissemination of this virus around the world ever since its outbreak in 2020, provide critical research criteria to assess the vulnerabilities of our current health system. The paper addresses our preparedness for the management of such acute health emergencies and the need to enhance awareness, about public health and healthcare mechanisms. In view of this unprecedented health crisis, distributed ledger and AI technology can be seen as one of the promising alternatives for fighting against such epidemics at the early stages, and with the higher efficacy. At the implementation level,… More >