Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (33)
  • Open Access


    The Primacy of Moringa (Moringa oleifera Lam.) in Boosting Nutrition Status and Immunity Defence Amidst the COVID-19 Catastrophe: A Perspective

    Hirdayesh Anuragi1, Rajesh Kumar Singhal2, Yashfa Tanveer3, Humaira Yasmin3, Ambati Srijan4, Alka Bharati1, Lal Chand5, Sukumar Taria1, Kunasekaran Rajarajan1, Asha Ram1, Arun Kumar Handa1, Ayyanadar Arunachalam1, Khalid Rehman Hakeem6,7,8,*, Deniz Özbilici9, Ayman EL Sabagh10,11,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.9, pp. 1831-1858, 2022, DOI:10.32604/phyton.2022.020540

    Abstract A severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led novel coronavirus disease (COVID-19) outbreak spread through China has become the biggest global public health challenge today. The virus upon several mutations has led to the resurgence of more infectious and lethal variants infecting over 298 million people with more than 5.46 million deaths worldwide by the end of December, 2021. Though vaccines are available, various preventive measures particularly a high body immunity is still extremely important which determines the likelihood of disease severity and subsequent recovery in the current and future pandemics. This review acknowledges the potentiality of miraculous Moringa oleiferaMore >

  • Open Access


    SARS-CoV-2 induced myocarditis: Current knowledge about its molecular and pathophysiological mechanisms


    BIOCELL, Vol.46, No.8, pp. 1779-1788, 2022, DOI:10.32604/biocell.2022.020009

    Abstract The existence of an inflammatory process in the heart muscle, related to a progressive worsening of myocardial function, different etiopathogenetic mechanisms concur and often overlap, thus making the diagnosis and the therapeutic approach complex. As the COVID-19 pandemic progresses, the effects of the disease on the organ systems and in particular on the cardiovascular system are becoming more and more profound. Cardiac involvement is a well-known event with a high percentage of findings in the heart’s magnetic field, even in asymptomatic areas. There are numerous uncertainties regarding their evolution, in the long and short term, due not only to a… More >

  • Open Access


    Secondary antiviral metabolites from fungi with special reference to coronaviruses


    BIOCELL, Vol.46, No.8, pp. 1979-1988, 2022, DOI:10.32604/biocell.2022.019301

    Abstract Profound inspection of the life forms on the earth teaches how to be the complexity of interrelationships among the various systems. Because of the emergence of novel viruses all the time and the inadequate of vaccines and antivirals, viral contagions are amongst the most causative diseases affecting people worldwide. Fungi exemplify a massive source of bioactive molecules as, many fungal secondary metabolities like Oxoglyantrypine, Carneic acid F, Scedapin C, Asteltoxin E, Phomanolide, Norquinadoline A and Quinadoline B have antiviral activity. This review deals with how secondary metabolites of fungi can help in the war against viruses in general and especially… More >

  • Open Access


    Intelligent Approach for Clustering Mutations’ Nature of COVID-19 Genome

    Ankur Dumka1, Parag Verma2, Rajesh Singh3, Anuj Bhardwaj4, Khalid Alsubhi5, Divya Anand6,7,*, Irene Delgado Noya7,8, Silvia Aparicio Obregon7,9

    CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 4453-4466, 2022, DOI:10.32604/cmc.2022.023974

    Abstract In December 2019, a group of people in Wuhan city of Hubei province of China were found to be affected by an infection called dark etiology pneumonia. The outbreak of this pneumonia infection was declared a deadly disease by the China Center for Disease Control and Prevention on January 9, 2020, named Novel Coronavirus 2019 (nCoV-2019). This nCoV-2019 is now known as COVID-19. There is a big list of infections of this coronavirus which is present in the form of a big family. This virus can cause several diseases that usually develop with a serious problem. According to the World… More >

  • Open Access


    Should we continue breastfeeding after SARS-CoV-2 infection or mRNA vaccination?


    BIOCELL, Vol.46, No.6, pp. 1425-1433, 2022, DOI:10.32604/biocell.2022.019868

    Abstract The coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed a potential threat to infant health. The World Health Organization recommended that the benefits of breastfeeding far outweigh the potential risk of transmission, but there is no denying that the current evidence is insufficient. Moreover, although the COVID-19 mRNA vaccine has played an effective role in protection against infection, individuals have increasing concerns about the safety of breastfeeding after vaccination, and which have caused some breastfeeding women to postpone vaccination or stop breastfeeding early. Thus, in this review, we provide an in-depth… More >

  • Open Access


    Investigation of SARS-CoV-2 Main Protease Potential Inhibitory Activities of Some Natural Antiviral Compounds Via Molecular Docking and Dynamics Approaches

    Nada M. Mostafa1,5,#, Muhammad I. Ismail2,#, Amr M. El-Araby3, Dina M. Bahgat1, Ahmed M. Elissawy1,5, Ahmed M. Mostafa4, Omayma A. Eldahshan1,5,*, Abdel Nasser B. Singab1,5,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.5, pp. 1089-1104, 2022, DOI:10.32604/phyton.2022.018239

    Abstract Coronaviruses caused an outbreak pandemic disease characterized by a severe acute respiratory distress syndrome leading to the infection of more than 200 million patients and the death of more than 4 million individuals. The primary treatment is either supportive or symptomatic. Natural products have an important role in the development of various drugs. Thus, screening of natural compounds with reported antiviral activities can lead to the discovery of potential inhibitory entities against coronaviruses. In the current study, an in-silico molecular docking experiment was conducted on the effects of some of these natural antiviral phytoconstituents, (e.g., procyanidin B2, theaflavin, quercetin, ellagic… More >

  • Open Access


    Prediction of COVID-19 Transmission in the United States Using Google Search Trends

    Meshrif Alruily1, Mohamed Ezz1,2, Ayman Mohamed Mostafa1,3, Nacim Yanes1,4, Mostafa Abbas5, Yasser El-Manzalawy5,*

    CMC-Computers, Materials & Continua, Vol.71, No.1, pp. 1751-1768, 2022, DOI:10.32604/cmc.2022.020714

    Abstract Accurate forecasting of emerging infectious diseases can guide public health officials in making appropriate decisions related to the allocation of public health resources. Due to the exponential spread of the COVID-19 infection worldwide, several computational models for forecasting the transmission and mortality rates of COVID-19 have been proposed in the literature. To accelerate scientific and public health insights into the spread and impact of COVID-19, Google released the Google COVID-19 search trends symptoms open-access dataset. Our objective is to develop 7 and 14-day-ahead forecasting models of COVID-19 transmission and mortality in the US using the Google search trends for COVID-19… More >

  • Open Access


    Blockchain and Artificial Intelligence Applications to Defeat COVID-19 Pandemic

    Mohammed Baz1, Sabita Khatri2, Abdullah Baz3, Hosam Alhakami4, Alka Agrawal2, Raees Ahmad Khan2,*

    Computer Systems Science and Engineering, Vol.40, No.2, pp. 691-702, 2022, DOI:10.32604/csse.2022.019079

    Abstract The rapid emergence of novel virus named SARS-CoV2 and unchecked dissemination of this virus around the world ever since its outbreak in 2020, provide critical research criteria to assess the vulnerabilities of our current health system. The paper addresses our preparedness for the management of such acute health emergencies and the need to enhance awareness, about public health and healthcare mechanisms. In view of this unprecedented health crisis, distributed ledger and AI technology can be seen as one of the promising alternatives for fighting against such epidemics at the early stages, and with the higher efficacy. At the implementation level,… More >

  • Open Access


    Predicting Genotype Information Related to COVID-19 for Molecular Mechanism Based on Computational Methods

    Lejun Gong1,2,*, Xingxing Zhang1, Li Zhang3, Zhihong Gao4

    CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.1, pp. 31-45, 2021, DOI:10.32604/cmes.2021.016622

    Abstract Novel coronavirus disease 2019 (COVID-19) is an ongoing health emergency. Several studies are related to COVID-19. However, its molecular mechanism remains unclear. The rapid publication of COVID-19 provides a new way to elucidate its mechanism through computational methods. This paper proposes a prediction method for mining genotype information related to COVID-19 from the perspective of molecular mechanisms based on machine learning. The method obtains seed genes based on prior knowledge. Candidate genes are mined from biomedical literature. The candidate genes are scored by machine learning based on the similarities measured between the seed and candidate genes. Furthermore, the results of… More >

  • Open Access


    A Vicenary Analysis of SARS-CoV-2 Genomes

    Sk Sarif Hassan1, Ranjeet Kumar Rout2, Kshira Sagar Sahoo3, Nz Jhanjhi4, Saiyed Umer5, Thamer A. Tabbakh6,*, Zahrah A. Almusaylim7

    CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 3477-3493, 2021, DOI:10.32604/cmc.2021.017206

    Abstract Coronaviruses are responsible for various diseases ranging from the common cold to severe infections like the Middle East syndromes and the severe acute respiratory syndrome. However, a new coronavirus strain known as COVID-19 developed into a pandemic resulting in an ongoing global public health crisis. Therefore, there is a need to understand the genomic transformations that occur within this family of viruses in order to limit disease spread and develop new therapeutic targets. The nucleotide sequences of SARS-CoV-2 are consist of several bases. These bases can be classified into purines and pyrimidines according to their chemical composition. Purines include adenine… More >

Displaying 11-20 on page 2 of 33. Per Page