MICHAEL HUBER^*, SANDRO CAPELLMANN

BIOCELL, Vol.46, No.5, pp. 1125-1129, 2022, DOI:10.32604/biocell.2022.018513 - 06 January 2022

Abstract Mast cells (MCs), hematopoietic cells of the myeloid lineage, are well-known for their pro-inflammatory nature contributing to the development of various allergic and autoimmune diseases. One of the characteristic receptors on MCs, the high-affinity receptor for IgE (FcεRI), is activated in its IgE-bound state via binding and crosslinking by polyvalent antigen. This results in its phosphorylation by the SRC family kinase LYN, initiating differential signaling pathways, eventually triggering immunological effector functions, such as degranulation and cytokine production. Few publications have reported on FcεRI-dependent but antigen-independent MC activation by antibody-mediated crosslinking of membrane molecules (e.g., transmembrane More >

HAN ZHAO¹, JING GUO¹, QINGJIA CHI², MENG FANG^1,*

BIOCELL, Vol.46, No.5, pp. 1245-1259, 2022, DOI:10.32604/biocell.2022.018117 - 06 January 2022

Abstract Hepatocellular carcinoma (HCC) is a worldwide malignant tumor that caused irreversible consequences. Tanshinone IIA has been shown to play a notable role in HCC treatment. However, the potential targets and associating mechanism of Tanshinone IIA against HCC remain unknown. We first screened out 105 overlapping genes by integrating the predicted targets of Tanshinone IIA from multiple databases and the differentially expressed genes of HCC from the Cancer Genome Atlas (TCGA) database. Then, we performed weighted gene co-expression network analysis (WGCNA) using the RNA-seq profiles of overlapping genes and HCC-related clinical information. 23 genes related to… More >

YUNLONG ZHANG^1,#, JINGWEI ZHANG^2,#, YU ZHU¹, BIN CAI^1,*

BIOCELL, Vol.46, No.5, pp. 1329-1338, 2022, DOI:10.32604/biocell.2022.015592 - 06 January 2022

Abstract Diabetic patients often exhibit delayed or incomplete progress in the healing of acute wounds, owing to poor blood perfusion. Platelet-rich plasma (PRP) has attracted much attention as a means to improve wound healing, because it contains high growth factor concentrations. However, the burst-like release of PRP growth factors results in a short half-life of these therapeutic proteins, thus greatly limiting the therapeutic effect. In this study, we prepared PRP from human umbilical cord blood and developed an in situ photocrosslinkable PRP hydrogel glue (HNPRP) by adding a photoresponsive hyaluronic acid (HA-NB) into PRP. The HNPRP hydrogel… More >

Mohammad Zubair Khan^1,*, Muhammad Awais Javed², Hamza Ghandorh¹, Omar H. Alhazmi¹, Khalid S. Aloufi³

Intelligent Automation & Soft Computing, Vol.33, No.1, pp. 305-315, 2022, DOI:10.32604/iasc.2022.024091 - 05 January 2022

Abstract Next-generation Intelligent Transportation Systems (ITS) use wirelessly connected vehicles for safety and non-safety applications such as autonomous driving, cooperative awareness, route guidance and multimedia transmissions. This network known as the Internet of Vehicles (IoVs) suffers from many challenges such as collisions due to hidden terminals, and interference from simultaneously transmitting vehicles. Moreover, the packet reception ratio of transmissions between vehicles is significantly reduced at high vehicle densities and severe fading scenarios. As safety applications require periodic broadcast of safety messages from each vehicle to all other vehicles in the neighborhood, the development of an efficient… More >

R. Manikandan^1,*, G. Ranganathan², V. Bindhu³

Intelligent Automation & Soft Computing, Vol.33, No.1, pp. 173-189, 2022, DOI:10.32604/iasc.2022.023922 - 05 January 2022

Abstract This paper presents development and analysis of different control strategies for smart automated system. The dynamic role of an electrical motor and sensor interfacing with wireless module becomes an essential element in a smart agriculture system to monitor various environmental parameters. The various key parameters such as temperature, humidity, air pressure, soil health and solar radiation are widely used to analyze the growth of plants and soil health based on different climate conditions. However, the smart development of an automatic system to measure these vital parameters provides a feasible approach and helps the farmers to… More >

V. Vijayal^1,*, K. Krishnamoorthi²

Intelligent Automation & Soft Computing, Vol.33, No.1, pp. 651-667, 2022, DOI:10.32604/iasc.2022.023890 - 05 January 2022

Abstract In high power medium voltage applications, the utilization of 5-H Bridge Multi-Level Inverter (MLI) has grown vastly in recent years. The 5-H Bridge MLI can effectively control link voltage as well as power factor. However, the inverter imparts harmonics owing to the high switching frequency. Hence Inductance Capacitance Inductance (LCL) filter is implemented at its output to mitigate harmonics in presence of non-linear load. It’s of highly important to choose LCL parameters wisely in order to attain good filtering effect. This work investigates the application of 5-H Bridge MLI with LCL filter at the output… More >

G. Chamundeeswari¹, S. Srinivasan^1,*, S. Prasanna Bharathi^1,2

Intelligent Automation & Soft Computing, Vol.33, No.1, pp. 515-534, 2022, DOI:10.32604/iasc.2022.023449 - 05 January 2022

Abstract Remote sensing (RS) is a very reliable and effective way to monitor the environment and landscape changes. In today’s world topographic maps are very important in science, research, planning and management. It is quite possible to detect the changes based on RS data which is obtained at two different times. In this paper, we propose an optimal technique that handles problems like urban green space destruction and detection of crop stress assessment. Firstly, the optimal preprocessing is performed on the given RS dataset, for image enhancement using geometric correction and image registration. Secondly, we propose… More >

T. Viveka^1,*, C. Christopher Columbus², N. Senthil Velmurugan³

Intelligent Automation & Soft Computing, Vol.33, No.1, pp. 535-547, 2022, DOI:10.32604/iasc.2022.022976 - 05 January 2022

Abstract Because of the increasing workload, people are having several clinical examinations to determine their health status, resulting in limited time. Here, we present a healthful consuming device based on rule mining that can modify your parameter dependency and recommend the varieties of meals that will boost your fitness and assist you to avoid the types of meals that increase your risk for sicknesses. Using the meals database, the data mining technique is useful for gathering meal energy from breakfast, after breakfast, lunch, after lunch, dinner, after dinner, and bedtime for ninety days. The purpose of… More >

Arun Kumar¹, Sumit Chakravarty², S. Suganya³, Mehedi Masud^4,*, Sultan Aljahdali⁴

Computer Systems Science and Engineering, Vol.42, No.2, pp. 483-492, 2022, DOI:10.32604/csse.2022.022899 - 04 January 2022

Abstract The implementation of Peak Average to Power Ratio (PAPR) reduction technologies will play an important role in the regularization of Fifth Generation (5G) radio communication. PAPR reduction in the advanced waveform will be the key part of designing a 5G network for different applications. This work introduces the simulation of an Advanced Partial Transmission Sequence (A-PTS) reduction techniques for Orthogonal Frequency Division Multiplexing (OFDM) and Filter Bank Multi-Carrier (FBMC) transmission schemes. In the projected A-PTS, the FBMC signals are mapped into the number of sub-blocks and Inverse Fast Fourier transform (IFFT) is performed to estimate More >

Mehran Mokhtari¹, Homayun Motameni^1,*, Peyman Bayat²

Computer Systems Science and Engineering, Vol.42, No.2, pp. 659-675, 2022, DOI:10.32604/csse.2022.021729 - 04 January 2022

Abstract In this study, a new feature is added to the smart message passing interface (SMPI) approach (SMPIA) based on the prioritization method, which can completely eliminate the task starvation and lack of sufficient resources problems through prioritizing the tasks. The proposed approach is based on prioritizing the tasks and the urgency of implementation. Tasks are prioritized based on execution time, workload, the task with a more sensitive priority is executed earlier by the free source. The idea of demand-bound functions (DBFs) was extended to the SMPIA setting based on partitions and caps. For each task,… More >