Kazuhiro Yamamoto^*, Takeshi Ioroi^*, Kazuaki Shinomiya^†, Ayaka Yoshida^*, Kenichi Harada^‡, Masato Fujisawa^‡, Tomohiro Omura^*, Yasuaki Ikemi^§, Shunsaku Nakagawa^§, Atsushi Yonezawa^§, Osamu Ogawa^¶, Kazuo Matsubara^§, Takuya Iwamoto^#, Kohei Nishikawa^**, Sayaka Hayashi^††, Daichi Tohara^††, Yoji Murakami^‡‡, Takanobu Motoshima^‡‡, Hirofumi Jono^††, Ikuko Yano^*§

Oncology Research, Vol.29, No.1, pp. 11-23, 2021, DOI:10.3727/096504022X16418911579334

Abstract We evaluated the association of signal transducer and activator of transcription 3 (STAT3) polymorphisms with the incidence of mammalian target of rapamycin (mTOR) inhibitor-induced interstitial lung disease (ILD) in patients with renal cell carcinoma (RCC). We also used lung-derived cell lines to investigate the mechanisms of this association. Japanese patients with metastatic RCC who were treated with mTOR inhibitors were genotyped for the STAT3 polymorphism, rs4796793 (−1697C/G). We evaluated the association of the STAT3 genotype with the incidence of ILD and therapeutic outcome. In the 57 patients included in the primary analysis, the ILD rate… More >

Zhong Yuan¹, Wei Fang^1,2,*, Yongming Zhao^3,*, Victor S. Sheng⁴

Journal on Artificial Intelligence, Vol.3, No.4, pp. 145-152, 2021, DOI:10.32604/jai.2021.026902 - 07 February 2022

Abstract Insects play an important role in the natural ecology, it is of great significance for ecology to research on insects. Nowadays, the invasion of alien species has brought serious troubles and a lot of losses to local life. However, there is still much room for improvement in the accuracy of insect recognition to effectively prevent the invasion of alien species. As the latest target detection algorithm, YOLOv5 has been used in various scene detection tasks, because of its powerful recognition capabilities and extremely high accuracy. As the problem of imbalance of feature maps at different… More >

Jiancheng Zou¹, Jiaxin Li^1,*, Juncun Wei¹, Zhengzheng Li¹, Xin Yang²

Journal on Artificial Intelligence, Vol.3, No.3, pp. 123-134, 2021, DOI:10.32604/jai.2021.027069 - 25 January 2022

Abstract Facial expression recognition is a research hot spot in the fields of computer vision and pattern recognition. However, the existing facial expression recognition models are mainly concentrated in the visible light environment. They have insufficient generalization ability and low recognition accuracy, and are vulnerable to environmental changes such as illumination and distance. In order to solve these problems, we combine the advantages of the infrared and visible images captured simultaneously by array equipment our developed with two infrared and two visible lens, so that the fused image not only has the texture information of visible… More >

Mengdan Ma^1,2, Yuchen Liu^1,*, Weiren Huang^1,*

Oncologie, Vol.23, No.4, pp. 463-492, 2021, DOI:10.32604/oncologie.2022.019415 - 31 December 2021

Abstract The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system, which is an RNA-guided nuclease system, plays an important role in the adaptive immune response of bacteria, and it is a rapidly developing gene editing technology. It has been widely used in a variety of cells, microorganisms, plants, and animals. This technique has helped to overcome the limitations of previous gene editing methods, and it has promoted the development of synthetic biology, genetics, and proteomics. The ability of the CRISPR-Cas system to modify the genetic components of a system has led to various practical applications, such… More >

J. V. Anand¹, R. Praveena^2,*, T. R. Ganesh Babu²

Journal on Internet of Things, Vol.3, No.4, pp. 139-147, 2021, DOI:10.32604/jiot.2021.016747 - 30 December 2021

Abstract The underwater wireless communication with the complexity of attenuation and low propagation speed makes resource constraints in networking sensor nodes and sink. Underwater Sensor Transmission with Attenuation Calculation using Non Orthogonal Multiple Access (UWSTAC-NOMA) protocol has been proposed. This protocol calculates channel gain along with attenuation in underwater channels and provides internetworking sensor for rate allocation minimizing interference. Successive Interference Cancellation has been used at the receiving sensor to decode the information sent. The network level performance of sensors and increasing the data rate improves the overall throughput. Simultaneously, connecting several sensors to sink based More >

Jianqiao Sheng¹, Mengzhu Xu², Jin Han^3,*, Xingyan Deng²

Journal on Big Data, Vol.3, No.4, pp. 183-190, 2021, DOI:10.32604/jbd.2021.024892 - 20 December 2021

Abstract Lightning disaster risk assessment, as an intuitive method to reflect the risk of regional lightning disasters, has aroused the research interest of many researchers. Nowadays, there are many schemes for lightning disaster risk assessment, but there are also some shortcomings, such as the resolution of the assessment is not clear enough, the accuracy rate cannot be verified, and the weight distribution has a strong subjective trend. This paper is guided by lightning disaster data and combines lightning data, population data and GDP data. Through support vector machine (SVM), it explores a way to combine More >

Peter M. Pinsky^*

CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.3, pp. 1329-1350, 2021, DOI:10.32604/cmes.2021.017740 - 25 November 2021

Abstract A fundamental problem for cells with their fragile membranes is the control of their volume. The primordial solution to this problem is the active transport of ions across the cell membrane to modulate the intracellular osmotic pressure. In this work, a theoretical model of the cellular pump-leak mechanism is proposed within the general framework of linear nonequilibrium thermodynamics. The model is expressed with phenomenological equations that describe passive and active ionic transport across cell membranes, supplemented by an equation for the membrane potential that accounts for the electrogenicity of the ionic pumps. For active ionic More >

Belal Almassri^1,*, Ali Safiyeh²

Structural Durability & Health Monitoring, Vol.15, No.4, pp. 349-366, 2021, DOI:10.32604/sdhm.2021.016889 - 23 November 2021

Abstract This study focuses on advanced finite element (FE) analyses on The Church of Nativity located in Bethlehem (Palestine), one of the most historic structures in the world. To ensure the model quality, a 3D FE model was created using two types of typical commercial software, DIANA FEA and SAP2000. From analyses, one of the expected behaviors for this kind of masonry structure “low modal period” was found. The seismic behavior of the church was studied using pushover analyses, which were conducted using DIANA FEA. The first unidirectional mass proportional load pattern was created in both… More >

Mian Ahmad Hanan^1,*, Arooj Arshad², Noshina Saleem³, Shamaila Asad²

International Journal of Mental Health Promotion, Vol.23, No.4, pp. 565-575, 2021, DOI:10.32604/IJMHP.2021.011168 - 28 October 2021

Abstract Previous research on media coverage of terrorism and its associated psychological consequences was explored internationally particularly after 9/11 attacks in the US. Also, the constructive role of resilience in this traumatic era has also been explored internationally. However, some studies have been conducted on the effect of media coverage of national terrorism on people that have endured a nearby terrorist attack. Moreover, knowledge about how the media coverage of terrorism, as a secondary source of evidence, can have devastated effects on native’s mental health and how resilience work in this relationship is rather limited. For… More >

Da Teng¹, Yunwen Feng^1,*, Cheng Lu^1,2, Chengwei Fei², Jiaqi Liu¹, Xiaofeng Xue^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.2, pp. 1029-1049, 2021, DOI:10.32604/cmes.2021.016945 - 08 October 2021

Abstract Turbine blisks are assembled using blades, disks and casings. They can endure complex loads at a high temperature, high pressure and high speed. The safe operation of assembled structures depends on the reliability of each component. Monte Carlo (MC) simulation is commonly used to analyze structural reliability, but this method needs to run thousands of computations. In order to assess the clearance reliability of assembled structures in an efficient and precise manner, the novel Kriging-based decomposed-coordinated (DC) (DCNK) approach is proposed by integrating the DC strategy, the Kriging model and the importance sampling-based Markov chain… More >