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  • Open Access

    RESIDENT’S CORNER

    Primary small cell carcinoma of the ureter

    Chiu Yen M. Chang1, Ken Reddy2, Katherine Chorneyko3, Anil Kapoor1

    Canadian Journal of Urology, Vol.12, No.2, pp. 2603-2606, 2005

    Abstract Primary small cell carcinoma of the ureter is a rare clinico-pathological entity. We present a report of primary ureteric small cell carcinoma and pathological correlates. More >

  • Open Access

    ARTICLE

    Compliance and outcome of patients with stage 1 non-seminomatous germ cell tumors (NSGCT) managed with surveillance programs in seven Canadian centres

    D. Scott Ernst1, Penny Brasher2, Peter M. Venner3, Piotr Czaykowski4, Malcolm J. Moore5, Leonard Reyno6, Eric Winquist1, Roanne Segal7, Desiree Hao8

    Canadian Journal of Urology, Vol.12, No.2, pp. 2575-2580, 2005

    Abstract Objective: We evaluate the impact of surveillance programs on the outcome of men with clinical stage 1 NSGCT following orchidectomy.
    Patients and methods: A retrospective review of 197 patients with a minimum of 2 years follow-up at seven cancer centres was conducted. Histological characteristics of the primary tumor were recorded for each patient. Surveillance protocols consisted of clinical assessments, chest X-rays, serum beta HCG (βHCG), alpha fetoprotein (αFP), and abdominopelvic CT. All clinic visits and test completions were tracked. In accordance with each centre's specific surveillance protocol, patient compliance was defined as missing no more than two assessments/year.
    More >

  • Open Access

    ARTICLE

    A population-based study of the waiting times for prostatectomy in Ontario

    D. Robert Siemens1, Karleen M. Schulze2, William J. Mackillop2, Michael D. Brundage2, Patti A. Groome2

    Canadian Journal of Urology, Vol.12, No.2, pp. 2568-2574, 2005

    Abstract Introduction and objective: Despite the high incidence of prostate cancer in Canada, there is currently limited information describing how these patients are being managed. The aim of this study was to review the surgical waiting times for radical prostatectomy in Ontario, utilizing existing population-based cancer databases, and to describe factors associated with prolonged waiting times.
    Methods: This is a retrospective, population-based, observational study of men diagnosed with prostate cancer in Ontario between 1980 and 2000. The sources of data include the Ontario Cancer Registry linked to hospital discharge data, as well as census data from Statistics Canada.… More >

  • Open Access

    RESIDENT’S CORNER

    Pseudo-tumoral eosinophilic cystitis in a 3 year-old girl

    Luis Antonio Guerra1, John Pike1, Guido Filler2, Kristin Udjus3, Joseph de Nanassy4, Michael Leonard1

    Canadian Journal of Urology, Vol.12, No.5, pp. 2846-2848, 2005

    Abstract Eosinophilic cystitis (EC) is an uncommon form of bladder inflammation. It is a rare disorder in children and fewer than 25 cases have been described in the literature. We report a case of eosinophilic cystitis mimicking a bladder tumor in a 3 year-old girl with symptoms of urinary frequency. The diagnosis was confirmed with pathology and she underwent clinical treatment with corticosteroids. More >

  • Open Access

    ARTICLE

    Development of prostate cancer quality indicators: a modified Delphi approach

    Anna R. Gagliardi1, Neil Fleshner2, Bernard Langer3, Hartley Stern3, Adalsteinn D. Brown4

    Canadian Journal of Urology, Vol.12, No.5, pp. 2808-2815, 2005

    Abstract Objectives: There is evidence of variation in both the processes and outcomes of prostate cancer care, resulting in possible harm to patients and increased costs to the health system. Care could be improved by first identifying critical, measurable indicators that correlate with quality of care. This work was conducted to develop indicators of prostate cancer care using a modified three-step Delphi approach.
    Methods: A 17-member multidisciplinary panel reviewed potential indicators extracted from the medical literature through two consecutive rounds of rating followed by consensus discussion. The panel then prioritized the indicators selected in the previous two rounds.
    Results:More >

  • Open Access

    ARTICLE

    Morphoquantitative evaluation of the duodenal myenteric neuronal population in rats fed with hypoproteic ration

    MARIA RAQUEL MARÇAL NATALI, SONIA LUCY MOLINARI, LUIZ CRISTIANO VALENTINI, MARCÍLIO HUBNER DE MIRANDA NETO.

    BIOCELL, Vol.29, No.1, pp. 39-46, 2005, DOI:10.32604/biocell.2005.29.039

    Abstract The purpose of this work was to analyze the morphoquantitative behavior of the neurons of the myenteric plexus, as well as the morphometry of the duodenal wall, in adult rats fed with normoproteic (22%) and hypoproteic (8%) rations, killed at the age of 345 days. For neuronal assessments duodenal wholemounts stained with the Giemsa method were used, and for the evaluation of the duodenal wall routine histological processing and staining with Hematoxilin-Eosin were employed. The means of the number of neurons in 80 microscopic fields (12.72 mm2 ) and of the size of the neuronal cell More >

  • Open Access

    ARTICLE

    Probability Methods for Estimation of Cleavage Fracture Toughness from Small Data Sets

    R. Moskovic1, P. E. J. Flewitt1,2

    Structural Durability & Health Monitoring, Vol.1, No.1, pp. 83-94, 2005, DOI:10.3970/sdhm.2005.001.083

    Abstract Consideration of the structural integrity is one of the inputs when evaluating potential solutions to plant problems. Structural integrity assessments of components forming the pressure boundaries of nuclear plant evaluate safety margins against cleavage fracture. These assessments consider the reserve factors between the applied stress and fracture toughness of the material as well as temperature margins between the operating temperature and the temperature at which the steel is ductile as defined by upper shelf behaviour. To carry out these structural integrity assessments, estimates of cleavage fracture toughness are required. The approach presented in this paper… More >

  • Open Access

    ARTICLE

    Criteria for the Assessment of Multiple Site Damage in Ageing Aircraft

    P. Horst1

    Structural Durability & Health Monitoring, Vol.1, No.1, pp. 49-66, 2005, DOI:10.3970/sdhm.2005.001.049

    Abstract The paper presents a Monte Carlo Simulation method for the assessment of Multiple Site Damage (MSD) and a subsequent attempt to find a way to interpret intermediate results of the Monte Carlo Simulation with respect to the criticality of scenarios. The basic deterministic part of the model is based on the compounding method, which is used in order to gain an acceptable computational effort. Some examples illustrate features of MSD scenarios and this allows to check an approach for feature detection via Wavelet transforms. This Wavelet transform approach shows some positive results in the interpretation More >

  • Open Access

    ARTICLE

    Contractile Torque as a Steering Mechanism for Orientation of Adherent Cells

    Dimitrije Stamenovic´ 1

    Molecular & Cellular Biomechanics, Vol.2, No.2, pp. 69-76, 2005, DOI:10.3970/mcb.2005.002.069

    Abstract It is well established that adherent cells change their orientation in response to non-uniform substrate stretching. Most observations indicate that cells orient away from the direction of the maximal substrate strain, whereas in some cases cells also align with the direction of the maximal strain. Previous studies suggest that orientation and steering of the cell may be closely tied to cytoskeletal contractile stress but they could not explain the mechanisms that direct cell reorientation. This led us to develop a simple, mechanistic theoretical model that could predict a direction of cell orientation in response to More >

  • Open Access

    ARTICLE

    Molecular-dynamics Study on Crack Growth Behavior Relevant to Crystal Nucleation in Amorphous Metal

    R. Matsumoto1, M. Nakagaki1, A. Nakatani2, H. Kitagawa3

    CMES-Computer Modeling in Engineering & Sciences, Vol.9, No.1, pp. 75-84, 2005, DOI:10.3970/cmes.2005.009.075

    Abstract In this paper, the internal structure-changes around the crack-tip and the pertinent crack growth behavior in an amorphous metal were studied by a molecular dynamics (MD) simulation. In order to perform a large scale calculation, the domain decomposition method was used for parallel calculation. The Finnis-Sinclair potential for$\alpha$-iron was used to describe the interatomic potential. Computed results show that nano-scaled crystalline phase grows around the crack-tip. The distribution of deformation zones and deformation mechanism are significantly altered. While grains are relatively small, they are not deformed, and the most amorphous-crystal interfaces have a large strain More >

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