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  • Open Access

    ARTICLE

    Boundary Conditions Generated by Dynamic Particles in SPH Methods

    A. J. C. Crespo1, M. Gómez-Gesteira1, R. A. Dalrymple2

    CMC-Computers, Materials & Continua, Vol.5, No.3, pp. 173-184, 2007, DOI:10.3970/cmc.2007.005.173

    Abstract Smoothed Particle Hydrodynamics is a purely Lagrangian method that can be applied to a wide variety of fields. The foundation and properties of the so called dynamic boundary particles (DBPs) are described in this paper. These boundary particles share the same equations of continuity and state as the moving particles placed inside the domain, although their positions and velocities remain unaltered in time or are externally prescribed. Theoretical and numerical calculations were carried out to study the collision between a moving particle and a boundary particle. The boundaries were observed to behave in an elastic More >

  • Open Access

    ARTICLE

    The case for dose escalation versus adjuvant androgen deprivation therapy for intermediate risk prostate cancer

    Tom Pickles1, Alan Pollack2

    Canadian Journal of Urology, Vol.13, Suppl.2, pp. 68-71, 2006

    Abstract Patients with intermediate-risk prostate cancer have a significant risk of biochemical failure after treatment with external beam radiation therapy. Two strategies to improve outcomes are radiation dose escalation and androgen deprivation therapy (ADT). This article discusses the evidence in favor of dose escalation.
    The case for radiation dose escalation has been established by several randomized studies, which show improved biochemical control (bNED) rates. Although late toxicity was also increased, it remains at clinically acceptable levels. The use of more focal methods of radiation, such as proton therapy and intensity modulated radiation therapy (IMRT), allows safe dose More >

  • Open Access

    ARTICLE

    Changing management of localized prostate cancer: a comparison survey of Ontario radiation oncologists

    Jarad Martin1, George Rodrigues2, Shawn Malone3, Gerard Morton4, Holly Campbell5, Juanita Crook1

    Canadian Journal of Urology, Vol.13, Suppl.2, pp. 26-33, 2006

    Abstract Background and purpose: Annual genitourinary radiation oncology meetings aim to assist in the dissemination of knowledge that may affect current practice. We aim to measure changes in practice approaches that have occurred while these meetings have been conducted.
    Materials and methods: A previously published survey from 2002 was sent to all genitourinary radiation oncologists in Ontario. Six prostate cancer patient scenarios were used: three definitive (low risk, intermediate risk, high risk), and three post-operative (extracapsular extension, margin positive, slowly rising PSA). There were 21 responders from seven cancer centers.
    Results: Using biological equivalent dose (BED), there is significant dose… More >

  • Open Access

    ARTICLE

    Obesity and prostate cancer

    Rebecca L. O’Malley, Samir S. Taneja

    Canadian Journal of Urology, Vol.13, Suppl.2, pp. 11-17, 2006

    Abstract The relationship between obesity and prostate cancer is currently a hotly debated topic, but despite the number of publications devoted to the topic, the actual nature of the relationship remains uncertain. Obesity has been shown to have a direct relationship with the incidence of prostate cancer in a number of studies but an equal number of studies have shown no association. The relationship is further obscured with recent findings that obesity in younger obese men may actually be protective against prostate cancer. Confounding factors include the lack of correlation of body mass index (BMI) as… More >

  • Open Access

    ARTICLE

    Timing cystectomy and perioperative chemotherapy in the treatment of muscle invasive bladder cancer

    Jonathan I. Izawa1,2,3, Joseph L. Chin1,2,3, Eric Winquist2,4

    Canadian Journal of Urology, Vol.13, Suppl.3, pp. 48-53, 2006

    Abstract Introduction: The ability of cystectomy to cure patients with muscle-invasive transitional cell carcinoma of the bladder (TCC) is diminished by the presence of occult micrometastases. Chemotherapy contributes to cure to the extent that it may eradicate these micrometastases. In the absence of methods to preoperatively stage TCC precisely or assess tumor biology, we review the current literature regarding the timing of cystectomy and use of perioperative chemotherapy. Based on this data, we suggest optimal and feasible strategies for treating TCC in a resource-constrained environment.
    Materials and methods: Systematic reviews of TCC were sought using electronic databases to… More >

  • Open Access

    RESIDENT’S CORNER

    Adenocarcinoma of the testicular adnexa presenting with metastatic disease

    Z. P. Joos, T. R. Pritchett, C. R. Porter, C. Isacson, V Picozzi, J. M. Corman

    Canadian Journal of Urology, Vol.13, No.1, pp. 2990-2992, 2006

    Abstract Primary epididymal adenocarcinoma is a rare malignancy with fewer than 30 documented cases. We report a case of a 57-year-old patient with a para testicular mass in the presence of retroperitoneal metastatic disease. Histology confirmed the presence of primary paratesticular adenocarcinoma. In this report we review the index case, the pertinent literature and discuss adjuvant therapy. More >

  • Open Access

    RESIDENT’S CORNER

    Renal pseudoaneurysm following percutaneous nephrolithotomy

    Glenn M. Cannon, Nikhil B. Amesur, Timothy D. Averch1

    Canadian Journal of Urology, Vol.13, No.1, pp. 2984-2987, 2006

    Abstract Percutaneous renal surgen; can be utilized as treatment for a variety of urologic conditions. Percutaneous nephrolithotomy remains the treatment of choice for many large and complex renal calculi. Despite having a low overall complication rate, postoperative bleeding can occur. We report a case of significant hemorrhage from a renal pseduoaneurysm in a patient requiring anticoagulation following percutaneous nephrolithotomy. The bleeding was controlled by percutaneous coil embolization. Current management recommendations of postoperative hemorrhage following percutaneous renal surgery are reviewed. More >

  • Open Access

    ARTICLE

    GU radiation oncologists consensus on bone loss from androgen deprivation

    Graeme G. Duncan1, Tom Corbett2, Himu Lukka2, Padraig Warde3, Tom Pickles1

    Canadian Journal of Urology, Vol.13, No.1, pp. 2962-2966, 2006

    Abstract The majority of GU radiation oncologists in Canada attended a consensus meeting in November 2004. The topic of osteoporosis in men receiving androgen deprivation therapy (ADT) for prostate cancer was identified as a key theme. A chaired session with keynote speakers and review of the evidence took place followed by open debate. Participants were provided with background information.
    Osteoporosis was defined as a T-score <= -2.5, but the importance of risk factors and clinical findings is noted. Dual DEXA is the current standard for assessment of bone density and relates well to fracture risk. The… More >

  • Open Access

    EDITORIAL COMMENT

    The Erectile Function Visual Analog Scale (EF-VAS): a disease-specific utility instrument for the assessment of erectile function - Page 3016

    Kok Bin Lim, Gerald B Brock

    Canadian Journal of Urology, Vol.13, No.2, pp. 3026-3026, 2006

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    The Erectile Function Visual Analog Scale (EF-VAS): a disease-specific utility instrument for the assessment of erectile function

    R. Casey1, J. E. Tarride2, M. A. Keresteci3, G. W. Torrance2,4

    Canadian Journal of Urology, Vol.13, No.2, pp. 3016-3025, 2006

    Abstract This article presents the responsiveness results of the Erectile Function Visual Analog Scale (EF-VAS) and reports, for the first time, utilities associated with erectile dysfunction (ED), as calculated by a disease-specific utility assessment. The EF-VAS is a new quality of life (QoL) instrument specific to ED that combines the strengths of the disease-specific approach to measuring QoL (greater disease relevance and responsiveness, with relevance to clinicians and patients) with those of preference-based assessments (generalizability and relevance to decision makers). The EF-VAS has demonstrated feasibility, reliability, and validity as reported in a recent publication.
    Methods: Standard instrument… More >

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