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  • Open Access

    ARTICLE

    Improving Routine Immunization Coverage Through Optimally Designed Predictive Models

    Fareeha Sameen1, Abdul Momin Kazi2, Majida Kazmi1,*, Munir A Abbasi3, Saad Ahmed Qazi1,4, Lampros K Stergioulas3,5

    CMC-Computers, Materials & Continua, Vol.70, No.1, pp. 375-395, 2022, DOI:10.32604/cmc.2022.019167 - 07 September 2021

    Abstract Routine immunization (RI) of children is the most effective and timely public health intervention for decreasing child mortality rates around the globe. Pakistan being a low-and-middle-income-country (LMIC) has one of the highest child mortality rates in the world occurring mainly due to vaccine-preventable diseases (VPDs). For improving RI coverage, a critical need is to establish potential RI defaulters at an early stage, so that appropriate interventions can be targeted towards such population who are identified to be at risk of missing on their scheduled vaccine uptakes. In this paper, a machine learning (ML) based predictive… More >

  • Open Access

    ARTICLE

    Exogenous Glycine Betaine Reduces Drought Damage by Mediating Osmotic Adjustment and Enhancing Antioxidant Defense in Phoebe hunanensis

    Yujie Yang1, Chengshi Huang2, Zuguo Ge3, Bengeng Zhou4, Guangju Su4, Chunling Liu4, Yongjun Fei1,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.1, pp. 129-148, 2022, DOI:10.32604/phyton.2022.016704 - 16 August 2021

    Abstract Drought stress negatively impacts growth and physiological processes in plants. The foliar application of glycine betaine (GB) is an effective and low-cost approach to improve the drought tolerance of trees. This study examined the effect of exogenously applied GB on the cell membrane permeability, osmotic adjustment, and antioxidant enzyme activities of Phoebe hunanensis Hand.-Mazz under drought stress. Two levels (0 and 800 mL) of water irrigation were tested under different applied GB concentrations (0, 50, 100, and 200 mM). Drought stress decreased the relative water content by 58.5% while increased the electric conductivity, malondialdehyde, proline, soluble proteins,… More >

  • Open Access

    ARTICLE

    AN EXPERIMENTAL STUDY ON A NEW HIGH-EFFICIENT SUPERCHARGER FOR SEAWATER REVERSE OSMOSIS DESALINATION DRIVEN DIRECTLY BY TIDAL ENERGY

    Changming Linga,b,*,†, Xiaobo Louc, Yin Zhongb

    Frontiers in Heat and Mass Transfer, Vol.16, pp. 1-6, 2021, DOI:10.5098/hmt.16.16

    Abstract To solve the issues of high-energetic consumption, high-cost and high-carbon emissions in the processes of reverse osmosis seawater desalination technology, this study proposed and implemented a tidal energy-gathering supercharger with the concept of using green tidal energy to directly produce high-pressure-seawater-driven reverse osmosis seawater desalination system. Compared with the traditional way of using tidal energy to produce electric power in order to produce high-pressure water for the system, this technology could save energy that may lost in two transferring process thus can improve the energy efficiency of the whole system, lower its running cost, and More >

  • Open Access

    REVIEW

    The role of YAP in the control of the metastatic potential of oral cancer

    USAMA SHARIF AHMAD, KARTHIK SARAVANAN, HONG WAN*

    Oncology Research, Vol.29, No.6, pp. 377-391, 2021, DOI:10.32604/or.2022.026085 - 10 November 2022

    Abstract The Yes-associated protein (YAP) is a downstream effector of the Hippo pathway and acts as a key transcription co-factor to regulate cell migration, proliferation, and survival. The Hippo pathway is evolutionarily conserved and controls tissue growth and organ size. Dysregulation and heterogeneity of this pathway are found in cancers, including oral squamous cell carcinoma (OSCC), leading to overexpression of YAP and its regulated proliferation machinery. The activity of YAP is associated with its nuclear expression and is negatively regulated by the Hippo kinase-mediated phosphorylation resulting in an induction of its cytoplasmic translocation. This review focuses More >

  • Open Access

    ARTICLE

    Fluid and Osmotic Pressure Balance and Volume Stabilization in Cells

    Peter M. Pinsky*

    CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.3, pp. 1329-1350, 2021, DOI:10.32604/cmes.2021.017740 - 25 November 2021

    Abstract A fundamental problem for cells with their fragile membranes is the control of their volume. The primordial solution to this problem is the active transport of ions across the cell membrane to modulate the intracellular osmotic pressure. In this work, a theoretical model of the cellular pump-leak mechanism is proposed within the general framework of linear nonequilibrium thermodynamics. The model is expressed with phenomenological equations that describe passive and active ionic transport across cell membranes, supplemented by an equation for the membrane potential that accounts for the electrogenicity of the ionic pumps. For active ionic More >

  • Open Access

    ARTICLE

    A Simplified Approach of Open Boundary Conditions for the Smoothed Particle Hydrodynamics Method

    Thanh Tien Bui1,*, Yoshihisa Fujita2, Susumu Nakata2

    CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.2, pp. 425-442, 2021, DOI:10.32604/cmes.2021.016766 - 08 October 2021

    Abstract In this paper, we propose a simplified approach of open boundary conditions for particle-based fluid simulations using the weakly compressible smoothed-particle hydrodynamics (SPH) method. In this scheme, the values of the inflow/outflow particles are calculated as fluid particles or imposed desired values to ensure the appropriate evolution of the flow field instead of using a renormalization process involving the fluid particles. We concentrate on handling the generation of new inflow particles using several simple approaches that contribute to the flow field stability. The advantages of the . -SPH scheme, specifically the particle shifting technique, were… More >

  • Open Access

    ARTICLE

    A 3-Node Co-Rotational Triangular Finite Element for Non-Smooth, Folded and Multi-Shell Laminated Composite Structures

    Zhongxue Li1,*, Jiawei Ji1, Loc Vu-Quoc2, Bassam A. Izzuddin3, Xin Zhuo1

    CMES-Computer Modeling in Engineering & Sciences, Vol.129, No.2, pp. 485-518, 2021, DOI:10.32604/cmes.2021.016050 - 08 October 2021

    Abstract Based on the first-order shear deformation theory, a 3-node co-rotational triangular finite element formulation is developed for large deformation modeling of non-smooth, folded and multi-shell laminated composite structures. The two smaller components of the mid-surface normal vector of shell at a node are defined as nodal rotational variables in the co-rotational local coordinate system. In the global coordinate system, two smaller components of one vector, together with the smallest or second smallest component of another vector, of an orthogonal triad at a node on a non-smooth intersection of plates and/or shells are defined as rotational… More >

  • Open Access

    ARTICLE

    The Effect of Injected Air Bubble Size on the Thermal Performance of a Vertical Shell and Helical Coiled Tube Heat Exchanger

    Saif S. Hasan1, Ali Sh. Baqir1, Hameed B. Mahood2,*

    Energy Engineering, Vol.118, No.6, pp. 1595-1609, 2021, DOI:10.32604/EE.2021.017433 - 10 September 2021

    Abstract In the present study, the effect of injecting air bubble size on the thermal performance of a vertical counter-current shell and coiled tube heat exchanger is experimentally investigated. The experiments were accomplished in a cylindrical shape heat exchanger with a 50 cm height and 15 cm outer diameter. Copper coil with 3.939 m equivalent length and 0.6 cm outer diameter was used to carry the hot fluid (water). Four different cold fluid (shell side) flow rates under laminar flow conditions (316 ≤ Re ≤ 1223), constant hot (coil side) flow rate fluid rates , four different injected… More >

  • Open Access

    ARTICLE

    Using Image Processing Technology and General Fluid Mechanics Principles to Model Smoke Diffusion in Forest Fires

    Liying Zhu*, Ang Wang, Fang Jin

    FDMP-Fluid Dynamics & Materials Processing, Vol.17, No.6, pp. 1213-1222, 2021, DOI:10.32604/fdmp.2021.017572 - 08 September 2021

    Abstract In the present study, the laws of smoke diffusion during forest fires are determined using the general principles of fluid mechanics and dedicated data obtained experimentally using an “ad hoc” imaging technology. Experimental images mimicking smoke in a real scenario are used to extract some “statistics”. These in turn are used to obtain the “divergence” of the flow (this fluid-dynamic parameter describing the amount of air that converges to a certain place from the surroundings or vice versa). The results show that the divergence of the smoke depends on the outside airflow and finally tends to More >

  • Open Access

    ARTICLE

    A Numerical Study on the Extinguishing Performances of High-Pressure Water Mist on Power-Transformer Fires for Different Flow Rates and Particle Velocities

    Yongheng Ku1, Jinguang Zhang2,3, Zhenyu Wang3,4, Youxin Li3,5, Haowei Yao3,5,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.17, No.6, pp. 1077-1090, 2021, DOI:10.32604/fdmp.2021.015779 - 08 September 2021

    Abstract In order to study the extinguishing performance of high-pressure-water-mist-based systems on the fires originating from power transformers the PyroSim software is used. Different particle velocities and flow rates are considered. The evolution laws of temperature around transformer, flue gas concentration and upper layer temperature of flue gas are analyzed under different boundary conditions. It is shown that the higher the particle velocity is, the lower the smoke concentration is, the better the cooling effect on the upper layer temperature of flue gas layer is, the larger the flow rate is and the better the cooling More >

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