Wassim M. Bazzi¹, Amy L. Tin², Daniel D. Sjoberg², Melanie Bernstein¹, Paul Russo¹

Canadian Journal of Urology, Vol.23, No.1, pp. 8151-8154, 2016

Abstract Introduction: To explore whether the association between preoperative neutrophil-to-lymphocyte ratio (NLR) elevation and worse survival is of use prognostically or merely a reflection of medical comorbidities in clear cell renal cell carcinoma (CC RCC).
Materials and methods: We identified 1970 patients treated at Memorial Sloan Kettering Cancer Center from 1998-2012 by partial or radical nephrectomy for nonmetastatic CC RCC. NLR was calculated by dividing absolute neutrophil count by absolute lymphocyte count; both were obtained from preoperative complete blood count. Uni- and multivariable Cox proportional hazards regression, which included established prognostic variables, were used to test for… More >

Gautum Agarwal, David Buethe, Christopher Russell, Adam Luchey, Julio M. Pow-Sang

Canadian Journal of Urology, Vol.23, No.2, pp. 8215-8219, 2016

Abstract Introduction: Up to 50% of patients will have disease reclassification while on active surveillance (AS) for their prostate cancer. Determining which patients will have reclassification that will impact their survival is difficult. We investigated clinicopathologic factors associated with disease reclassification and differences in both overall and metastasis free survival between those treated and those remaining on AS.
Materials and methods: We performed a retrospective review of patients who were enrolled in an AS protocol between 1994 and 2000. Inclusion criteria for AS were: < cT2a disease, PSA < 10 ng/mL, < 50% of single core involvement, and… More >

Yue-shen Wang^*1, Jing Tian^†1, Yong Han^†, Shu-mei Han^†, Sheng-bin Shi^†

Oncology Research, Vol.24, No.2, pp. 129-135, 2016, DOI:10.3727/096504016X14618564639213

Abstract We evaluated the efficacy and feasibility of the combination of gemcitabine plus vinorelbine in patients with platinum-based chemotherapy-refractory esophageal cancer. We enrolled 35 patients who received gemcitabine plus vinorelbine as second-line treatment after platinum-based chemotherapy failure between May 2009 and April 2012. Dosage: gemcitabine 1,000 mg/m² plus vinorelbine 25 mg/m² ; all drugs were administered on days 1 and 8 of a 21-day cycle, and this was continued until failure or unacceptable toxicity. A total of 125 cycles of treatment were administered, and all patients received at least two cycles of treatment (two to five cycles;… More >

Jiahao Su^*, Meiqin Cai^*, Wensheng Li^*, Bo Hou^†, Haiyong He^†, Cong Ling^†,Tengchao Huang^†, Huijiao Liu^†, Ying Guo^*

Oncology Research, Vol.24, No.2, pp. 117-128, 2016, DOI:10.3727/096504016X14612603423511

Abstract Glioblastoma (GBM) is the most common primary malignant brain tumor that nearly always results in a bad prognosis. Temozolomide plus radiotherapy (TEM+RAD) is the most common treatment for newly diagnosed GBM. With the development of molecularly targeted drugs, several clinical trials were reported; however, the efficacy of the treatment remains controversial. So we attempted to measure the dose of the molecularly targeted drug that could improve the prognosis of those patients. The appropriate electronic databases (PubMed, MEDLINE, EMBASE, and the Cochrane Library) were searched for relevant studies. A meta-analysis was performed after determining which studies… More >

Gangcan Li, Yanping Song, Yunjie Zhang, Hao Wang, Jia Xie

Oncology Research, Vol.24, No.2, pp. 109-116, 2016, DOI:10.3727/096504016X14611963142254

Abstract Acute myeloid leukemia (AML) is the most lethal hematological malignancy, and the occurrence of chemoresistance prevents the achievement of complete remission following the standard therapy. MicroRNAs have been extensively investigated as critical regulators of hematopoiesis and leukemogenesis, and they represent a promising strategy for AML therapy. In this study, we identified miR-34b as a novel regulator in myeloid proliferation and apoptosis of leukemic cells. We found that miR-34b was developmentally upregulated in plasma and myeloid cells of healthy subjects, while it was significantly reduced in blood samples of patients with AML and AML cell lines.… More >

Perissé P¹, R Lovey², ML Molinelli¹, M Scandaliaris²

Phyton-International Journal of Experimental Botany, Vol.83, pp. 275-281, 2014, DOI:10.32604/phyton.2014.83.275

Abstract Cologania broussonetii (Balb.) DC. stands out as valuable perennial, native forage that grows in northwestern Argentina, Cordoba hills and San Luis Province. The objectives of this study were to establish the vegetative and reproductive structures in function of the strategies and survival tactics of Cologania broussonetii. The specimens were collected in the Pan de Azúcar loaf mountain, Córdoba, and in the experimental plots of the FCA, UNC, and were then deposited in the Herbarium ACOR and in the Seed Collection. Seedlings were obtained from germination assays. Cross section cuts were performed on the survival structures of adult… More >

JOSÉ LUIS ARREDONDO-FIGUEROA¹, LAURA GEORGINA NÚÑEZ-GARCÍA², PALOMA ADRIANA HEREDIA-GUZMÁN³ AND JESÚS T. PONCE-PALAFOX⁴.

BIOCELL, Vol.36, No.3, pp. 105-111, 2012, DOI:10.32604/biocell.2012.36.105

Abstract Chirostoma jordani is a native annual species inhabiting lacustrine waters of the Central Mexico Plateau. It is widely distributed and is currently facing high environmental pressures. Five experiments were performed to study the reproductive performance of this species. Four of the experiments were conducted in 270-L indoor recirculation tanks. Two males and one female at the first stage of reproduction were included in each test. A photoperiod of 14 light hours and 10 dark hours was used. In a fifth experiment, 10 females and 15 males were kept in an outdoor 3,000-L recirculation tank under natural… More >

Perissé P¹, RJ Lovey², CV Arias³, M Scandaliaris², ML Molinelli¹

Phyton-International Journal of Experimental Botany, Vol.80, pp. 73-78, 2011, DOI:10.32604/phyton.2011.80.073

Abstract Dicliptera squarrosa Nees, “canario rojo”, “coral de campo” or “ajicillo”, is a perennial native herb of the north, center and east of Argentina. It is cited as an ornamental, apiarian, emergency forage plant, and as a glyphosate-tolerant weed. The objectives were to characterize the seed and seedling of D. squarrosa and to establish the relationships with the structures that ensure its survival. The materials were treated with the conventional methodology to perform morphological studies, using stereoscopically and optical microscopy. The germination assays were carried out to determine the germination percentage and the germination type. The weight of… More >

P. E. Murray¹, F. Garcia-Godoy¹

Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 139-140, 2006, DOI:10.32604/mcb.2006.003.139

Abstract This article has no abstract. More >