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  • Open Access

    EDITORIAL

    Prostate cancer detection: beware of the low PSA

    Gabriel P. Haas

    Canadian Journal of Urology, Vol.14, No.3, pp. 3534-3534, 2007

    Abstract This article has no abstract. More >

  • Open Access

    MINIMALLY INVASIVE AND ROBOTIC SURGERY

    Robot-assisted partial cystectomy for the treatment of urachal carcinoma

    Danny M. Rabah

    Canadian Journal of Urology, Vol.14, No.4, pp. 3640-3642, 2007

    Abstract The traditional treatment of choice for urachal carcinoma has been either an open radical cystectomy or the more recently accepted extended partial cystectomy and umbilectomy. Recently a laparoscopic technique has been reported. We report for the first time a robot-assisted technique for an extended partial cystectomy with en bloc umbilectomy for the management of urachal carcinoma in a 49-year-old man. More >

  • Open Access

    MINIMALLY INVASIVE AND ROBOTIC SURGERY

    Impact of previous inguinal hernia repair on transperitoneal robotic prostatectomy

    Rajesh G. Laungani, Sanjeev Kaul, Fred Muhletaler, Ketan K. Badani, James Peabody, Mani Menon

    Canadian Journal of Urology, Vol.14, No.4, pp. 3635-3639, 2007

    Abstract Objective: Several investigators have noted that previous inguinal hernia repair with or without the use of prosthetic mesh might be a relative contraindication for open or laparoscopic radical prostatectomy due to the presence of adhesions and the difficulty of tissue dissection. We aimed to evaluate the impact of previous hernia repair on the performance and feasibility of robotic prostatectomy.
    Materials and methods: We performed a retrospective analysis of 354 patients who underwent robotic prostatectomy at our institution. The three patient groups were: 292 patients who had no prior hernia repair (group 1), 50 patients who had prior… More >

  • Open Access

    ARTICLE

    Cystectomy in the ninth decade: operative results and long-term survival outcomes

    Frederick P. Mendiola, Kevin C. Zorn, Ofer N. Gofrit, Albert A. Mikhail, Marcelo A. Orvieto, Lambda P. Msezane, Gary D. Steinberg

    Canadian Journal of Urology, Vol.14, No.4, pp. 3628-3634, 2007

    Abstract Introduction: Radical cystectomy (RC) with urinary diversion remains as one of the more complex urological procedures despite considerable progress in surgical technique. Increasing patient age, along with associated age-related comorbidities, may portend a poor outcome in those undergoing such complicated surgical procedures. Herein, we report our experience with radical cystectomy in the elderly population.
    Methods: We retrospectively reviewed our RC results from 1995 to 2003. Patients ≥80 years old were included in this analysis. Perioperative outcomes, as well as overall and disease-free survival were evaluated.
    Results: A total of 517 patients underwent RC with urinary diversion during… More >

  • Open Access

    MINIMALLY INVASIVE AND ROBOTIC SURGERY

    Prostate weight: an independent predictor for positive surgical margins during robotic-assisted laparoscopic radical prostatectomy

    Lambda P. Msezane, Ofer N. Gofrit, Shang Lin, Arieh L. Shalhav, Gregory P. Zagaja, Kevin C. Zorn

    Canadian Journal of Urology, Vol.14, No.5, pp. 3697-3701, 2007

    Abstract Introduction: Pre-operative prediction of pathological stage represents the cornerstone of prostate cancer management. Patient counseling is routinely based on pre-operative PSA, Gleason score and clinical stage. In this study, we evaluated whether prostate weight (PW) is an independent predictor of extracapsular extension (ECE) and positive surgical margin (PSM).
    Methods: Between February 2003 and November 2006, 709 men underwent robotic-assisted laparoscopic radical prostatectomy (RLRP). Pre-operative parameters (patient age, pre-operative PSA, biopsy Gleason score, clinical stage) as well as pathological data (prostate weight, pathological stage) were prospectively gathered after internal-review board (IRB) approval. Evaluation of the influence of… More >

  • Open Access

    MINIMALLY INVASIVE AND ROBOTIC SURGERY

    Robot-assisted radical cystectomy versus open radical cystectomy: assessment of postoperative pain

    Khurshid A. Guru1,4, Gregory E. Wilding3,6, Pamela Piacente1, Jannah Thompson4, Wei Deng6, Hyung L. Kim1,4, James Mohler1,4, Kathleen O’Leary2,5

    Canadian Journal of Urology, Vol.14, No.6, pp. 3753-3756, 2007

    Abstract Introduction: To date, no study has compared postoperative pain and requirement for pain medications in open versus robot-assisted radical cystectomy. Patient reported pain and opiate use were reviewed retrospectively using prospectively collected data from postoperative day one to day of discharge.
    Materials and methods: Twenty consecutive robot-assisted radical cystectomy patients were compared to the prior 20 patients who underwent open radical cystectomy. Data was collected prospectively to determine opiate requirements and pain scores in each group. Daily opiate use was converted to morphine sulfate equivalents (MSE) to facilitate comparison. A Likert pain perception scale was used to… More >

  • Open Access

    ARTICLE

    Anew suture technique for anastomosis in radical retropubic prostatectomy and early removal of urethral catheter

    Levent N. Türkeri, Yusuf Temiz, Cenk M. Yazici, Ilker Tinay

    Canadian Journal of Urology, Vol.14, No.6, pp. 3734-3738, 2007

    Abstract Introduction: A modified suture technique for urethro-vesical anastomosis during radical retropubic prostatectomy was developed and utilized in a cohort of patients. Comparative analysis of postoperative outcome was performed with a previous group of patients who had an anastomosis with the conventional technique.
    Material and methods: A consecutive group of patients who underwent radical retropubic prostatectomy in our department with the diagnosis of localized prostate cancer was included in this retrospective study. Urethro-vesical anastomosis was performed either with the new or conventional method (CM). Outcome data of these two different patient sets were compared.
    Results: One-hundred and one… More >

  • Open Access

    ARTICLE

    Screening men for prostate cancer and colorectal cancer: is practice evidence-based?

    Felix K-H. Chun1, Nazareno Suardi1, Paul Perrotte2, Thierry Lebeau2, Jean-Pierre Guay2, Serge Benayoun2, Alvaro Ramirez2, François Bénard2, Michael McCormack2, Luc Valiquette2, Pierre Karakiewicz1,2

    Canadian Journal of Urology, Vol.14, No.6, pp. 3727-3733, 2007

    Abstract Introduction: Controversy persists about whether men should be screened for prostate cancer. On the other hand, the benefit of colorectal cancer screening has been proven for men starting at age 50. We aimed to examine the rate of exposure to previous screening tests for prostate cancer and colorectal cancer in a cohort of men living in Quebec.
    Materials and methods: As part of an event promoting early prostate cancer detection, 347 men aged 50 to 69 without an established diagnosis of prostate cancer agreed to reply to questions in a previously validated questionnaire. The self-administered questionnaire, which… More >

  • Open Access

    ARTICLE

    Chlorination: Phytotoxicity and effects on the production and quality of Lactuca sativa var. Mantecosa grown in a closed, soil-less system

    Premuzic1 Z, HE Palmucci1, J Tamborenea1, M Nakama2

    Phyton-International Journal of Experimental Botany, Vol.76, pp. 103-117, 2007, DOI:10.32604/phyton.2007.76.103

    Abstract The addition of chlorine constitutes an economical disinfection method for closed, soil-less systems. Three quantities of sodium hypochlorite (0.55, 5.5 and 11 ppm) were applied to closed, soil-less greenhouse- grown lettuce (Lactuca sativa), to study the effect on its production (fresh weight and dry matter) and some commercial and nutritional quality factors (phytotoxicity, Vitamin C, nitrates). Sodium hypochlorite was weekly added within the nutrient solution, and the chemical properties (pH, EC and chlorides) of the recycled solution were measured. Damage to leaves was evaluated 15 days before harvest. Chlorination produced different effects regarding both production and… More >

  • Open Access

    ARTICLE

    Technical Note : Prolonged exposure of human embryonic stem cells to heat shock induces necrotic cell death

    B.C. Heng*, K.J. Vinoth*, K. Lu*, X. Deng*, Z. Ge*, B.H. Bay**, T. Cao*

    BIOCELL, Vol.31, No.3, pp. 405-410, 2007, DOI:10.32604/biocell.2007.31.405

    Abstract We investigated the effects of prolonged heat shock treatment on human embryonic stem cell (hESC) viability. The hESC viability steadily declined with longer exposure to heat shock treatment (43ºC). After 4 h of exposure to heat shock at 43ºC, only 56.2 ± 1.5% of cells were viable. Viability subsequently declined to 37.0 ± 3.3% and 3.5 ± 0.7% after 8 h and 16 h, respectively of heat shock treatment at 43ºC. Transmission electron micrographs showed that the morphology of the dead/dying cells after heat shock treatment was characteristic of cellular necrosis with an uncondensed chromatin… More >

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