Thomas J. Guzzo¹, Matthew J. Resnick¹, Daniel J. Canter¹, Arturo Balandra¹, Meredith R. Bergey¹, Laurie Magerfl eisch¹, John E. Tomaszewski², David J. Vaughn³, S. Bruce Malkowicz¹

Canadian Journal of Urology, Vol.17, No.6, pp. 5465-5471, 2010

Abstract Introduction: Radical cystectomy (RC) remains the gold standard treatment for patients with muscle-invasive bladder cancer. Unfortunately, a significant proportion of patients will have lymph node involvement at the time of RC. We set out to determine the impact of adjuvant cisplatin-based chemotherapy (AC) in a cohort of lymph node positive patients following RC.
Patients and methods: We reviewed our RC database and isolated patients with lymph node positive disease at the time of RC. Univariate and multivariable analysis was performed to identify predictors of poor outcome in patients receiving AC. Overall survival (OS), disease specific survival (DSS)… More >

Jack Barkin

Canadian Journal of Urology, Vol.17, No.6, pp. 5446-5446, 2010

Abstract This article has no abstract. More >

Adam P. Klausner^1,2, Blake B. Anderson¹, Paul G. Espy¹, Vidal M. Despradel^1,2, B. Mayer Grob^1,2

Canadian Journal of Urology, Vol.17, No.6, pp. 5442-5446, 2010

Abstract Introduction: The purpose of this study was to evaluate the utility of prostate-specific antigen (PSA) screening for prostate cancer after subcapsular prostatectomy.
Materials and methods: Data from 41 consecutive patients who underwent subcapsular prostatectomy at a single institution over a 15 year period were collected retrospectively. Patients were categorized into benign and malignant groups based on a diagnosis of prostate cancer identified in the surgical specimen or during subsequent follow up. Collected data included patient age, preoperative and postoperative PSA values, prostate volume determined by surgical specimen weight, and pathologic diagnosis. Preoperative and postoperative PSA velocities were… More >

Siddhartha Baxi, Charles Catton

Canadian Journal of Urology, Vol.17, No.6, pp. 5436-5441, 2010

Abstract Introduction: Level 1 evidence demonstrates the benefit of postoperative radiotherapy (PORT) for pT3 disease and positive margins. The role of androgen deprivation therapy (ADT) after PORT remains to be defined from results of ongoing randomized trials. This study was undertaken to determine the factors influencing the current use of ADT after PORT amongst Canadian radiation oncologists.
Methods: An institutional survey was emailed to the Genito-urinary Radiation Oncologists Group of Canada (GUROC), designed to assess the likelihood of prescribing ADT in early and delayed PORT scenarios with variations in disease prognosticators. Analysis used descriptive statistics.
Results: Majority (94%) do… More >

Je-Chin Han^*, Akhilesh P. Rallabandi

Frontiers in Heat and Mass Transfer, Vol.1, No.1, pp. 1-21, 2010, DOI:10.5098/hmt.v1.1.3001

Abstract Film cooling is widely used to protect modern gas turbine blades and vanes from the ever increasing inlet temperatures. Film cooling involves a very complex turbulent flow-field, the characterization of which is necessary for reliable and economical design. Several experimental studies have focused on gas turbine blade, vane and end-wall film cooling over the past few decades. Measurements of heat transfer coefficients, film cooling effectiveness values and heat flux ratios using several different experimental methods have been reported. The emphasis of this current review is on the Pressure Sensitive Paint (PSP) mass transfer analogy to More >

Cerna¹ E, Y Ochoa², R Mendoza¹, MH Badii³, G Gallegos¹, J Landeros¹

Phyton-International Journal of Experimental Botany, Vol.79, pp. 147-152, 2010, DOI:10.32604/phyton.2010.79.147

Abstract Protein assays were conducted on Tetranychus urticae Koch, as potential resistance detection tools to plaguicides. This is a phytophagous mite that feeds on a large variety of plants. Experiments were carried out using a pesticide susceptible and three field crop strains of T. urticae. Protein was measured by colorimetric assays, using Kit-II from Bio-Rad, with bovine serum albumin (BSA) as standard. Homogenates were prepared using 10, 30, 50, 100, 300, 500 and 800 mites, with 30 replicates each. Linearity was obtained for the standard curve of the different methods, and r² values ranged from 0.877 to 0.985. The More >

Hernández-León R, I Velázquez-Sepúlveda, MC Orozco-Mosqueda, G Santoyo

Phyton-International Journal of Experimental Botany, Vol.79, pp. 133-139, 2010, DOI:10.32604/phyton.2010.79.133

Abstract Soil is a complex system that includes a great number and diversity of microorganisms. Until recently, only a small percentage of the bioma was known and could be studied. Currently, it is possible to have a deeper knowledge of all that unknown genomic material with the development of new tools, like metagenomics. New molecules have been discovered with various biotechnological applications, and knowledge of the diverse microbiological interactions in several environments, some of them with extreme life conditions, is much higher. We analyze the most recent literature in the field of metagenomics in this study, More >

A.V. Ekhlakov², O.M. Khay², Ch. Zhang², J. Sladek³, V. Sladek³

Structural Durability & Health Monitoring, Vol.6, No.3&4, pp. 329-350, 2010, DOI:10.3970/sdhm.2010.006.329

Abstract In this paper, transient crack analysis in two-dimensional, isotropic, continuously non-homo -ge -neous and linear elastic functionally graded materials is presented. A boundary-domain element method based on boundary-domain integral representations is developed. The Laplace-transform technique is utilized to eliminate the dependence on time. Laplace-transformed fundamental solutions of linear coupled thermoelasticity for isotropic, homogeneous and linear elastic solids are applied to derive boundary-domain integral equations. The numerical implementation is performed by using a collocation method for the spatial discretization. The time-dependent numerical solutions are obtained by the Stehfest's inversion algorithm. For an edge crack in a More >

Essam E Khalil¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.15, No.2, pp. 47-56, 2010, DOI:10.3970/icces.2010.015.047

Abstract The cultural heritage left by the Egyptian Pharaohs in the tombs of the Valley of the Kings represents some of the key elements of the Egyptian cultural and tourism wealth and standing monuments demonstrating the wealth and technology of the pharaohs. These tombs were prepared to bury the Kings' mummies and artifacts for eternal life. Many of the wall paintings identifying the various ancient rituals and life style are in good conditions as the tombs were only recently opened to the public and resulted, in many instances, to dramatic deterioration of the wall paintings due More >

R. M. Ardito Marretta^*, F. Ales^†

Molecular & Cellular Biomechanics, Vol.7, No.4, pp. 225-266, 2010, DOI:10.3970/mcb.2010.007.225

Abstract In this paper, cell cycle in higher eukaryotes and their molecular networks signals both inG1/SandG2/Mtransitions are replicatedin silico. Biochemical kinetics, converted into a set of differential equations, and system control theory are employed to design multi-nested digital layers to simulate protein-to-protein activation and inhibition for cell cycle dynamics in the presence of damaged genomes. Sequencing and controlling the digital process of four micro-scale species networks (p53/Mdm2/DNA damage, p21mRNA/cyclin-CDK complex, CDK/CDC25/wee1/ SKP2/APC/CKI and apoptosis target genes system) not only allows the comprehension of the mechanisms of these molecule interactions but paves the way for unraveling the… More >