Khurshid A. Guru^1,2, Adam E. Perlmutter¹, Zubair M. Butt¹, James O. Peabody³

Canadian Journal of Urology, Vol.15, No.2, pp. 4000-4003, 2008

Abstract Introduction: To describe a technique that may facilitate neurovascular bundle preservation during robot-assisted radical prostatectomy.
Materials and methods: From December 2007 to January 2008, 10 patients underwent robot-assisted radical prostatectomy with bilateral nerve preservation. Hydrodissection of the neurovascular bundle was performed by injecting a 1:10000 epinephrine solution diluted in 0.9% normal saline into the lateral prostatic pedicle with an injection cannula needle (Wolf®). Operative time, blood loss and margin status were assessed when this new technique was utilized. Erectile function status will be analyzed in the future.
Results: Ten potent patients underwent bilateral nerve-sparing robot-assisted radical prostatectomy… More >

Edouard J. Trabulsi¹, Robert A. Linden¹, Leonard G. Gomella¹, Davis E. McGinnis², Stephen E. Strup³, Costas D. Lallas¹

Canadian Journal of Urology, Vol.15, No.2, pp. 3994-3999, 2008

Abstract Purpose: The addition of robotic assistance with the da Vinci surgical system for performing laparoscopic radical prostatectomy has been reported to improve surgical outcomes. In order to evaluate the benefit of robotic assistance to improve cancer control in a center with an established laparoscopic radical prostatectomy program, we evaluated the incidence of positive surgical margins in both transperitoneal laparoscopic (LRP) and robotically assisted laparoscopic radical prostatectomy (RALP).
Materials and methods: We performed an Institutional Review Board (IRB) approved, retrospective review of 247 men with clinically localized prostate cancer treated with either a LRP or a RALP from… More >

Gabriel P. Haas

Canadian Journal of Urology, Vol.15, No.2, pp. 3950-3950, 2008

Abstract This article has no abstract. More >

David B. Samadi¹, Bilal Chughtai², Ardavan Akhavan³, Khurshid Guru⁴, Jamil Rehman⁵

Canadian Journal of Urology, Vol.15, No.3, pp. 4109-4111, 2008

Abstract Primary soft tissue sarcomas of the genitourinary tract are rarely seen, especially in the seminal vesicle. While sarcomas have been reported in the seminal vesicle, this is the fi rst report of a smooth muscle neoplasm, of uncertain malignant potential, involving the seminal vesicle. The fi nding was incidental, following robotic-assisted radical retropubic prostatectomy for prostate cancer. To our knowledge, this is also the fi rst report of a primary seminal vesicle tumor found following radical prostatectomy. A clinical case review and a brief review of the literature are presented. More >

Bertram Yuh¹, Rajesh Laungani², Adam Perlmutter³, Daniel Eun², James O. Peabody², James L. Mohler³, Hans Stricker², Khurshid A. Guru³

Canadian Journal of Urology, Vol.15, No.3, pp. 4101-4105, 2008

Abstract Introduction/objective: Simple prostatectomy continues to be an effective surgical option for patients with symptomatic high volume benign prostatic hyperplasia. Recent trends towards minimally invasive urologic surgery, in particular for prostate cancer, have created surgical alternatives with additional potential benefits. We report on the feasibility of robot-assisted retropubic prostatectomy.
Materials and methods: This series consists of three cases of simple prostatectomy performed through a robot-assisted retropubic (Millin) approach at two institutions. All patients had preoperative bothersome lower urinary tract symptoms with two patients presenting in urinary retention. Average preoperative transrectal ultrasound estimated prostate volume exceeded 300 cm³. All patients… More >

Mario F. Chammas Jr.¹, Fernando J. Kim¹, Aurelio Barbarino², Nicolas Hubert³, Benoît Feuillu³, Alain Coissard⁴, Jacques Hubert³

Canadian Journal of Urology, Vol.15, No.3, pp. 4097-4100, 2008

Abstract Objectives: To evaluate the feasibility and safety of robot-assisted laparoscopic partial cystectomy for the treatment of rectal and bladder endometriosis.
Materials and methods: A 23-year-old female with history of infertility and pelvic pain was found to have a 4 cm bladder mass and rectal nodule on pelvic ultrasonography. Patient denied any other genitourinary symptoms. Cystoscopy and bladder mass biopsy revealed endometriosis. After failure to suppressive hormonal medical therapy a partial cystectomy and resection of a rectal lesion was performed with robotic assistance (da Vinci). The procedure included excision of an ovarian cyst and several peritoneal endometrioid implants.
Results: More >

Jamil Rehman¹, Khurshid Guru², Bilal Chughtai³, Ridwan Shabsigh⁴, David Samadi⁵

Canadian Journal of Urology, Vol.15, No.5, pp. 4263-4265, 2008

Abstract Purpose: We present our initial experience with performing robotic-assisted prostatectomies in men with a 3-piece inflatable penile prosthesis with a pelvic reservoir.
Material and methods: Four patients underwent transperitoneal robotic-assisted radical prostatectomies with a penile prosthetic implant in place. The reservoir was left inflated for easy identification. A flaccid reservoir may be more difficult to identify, and be prone to damage. The reservoir was left attached to the abdominal wall. Dissection was performed outside the fibrous capsule of the reservoir. The tissue around the capsule of the reservoir peeled off without difficulty. Cutting current close to the… More >

Kaili Mao¹, Cécile Badoual², Philippe Camparo³, Nicolas Barry Delongchamps¹, Annick Vieillefond⁴, Anh-Tuan Dinh-Xuan⁵, Michaël Peyromaure¹

Canadian Journal of Urology, Vol.15, No.5, pp. 4257-4262, 2008

Abstract Objectives: To study the prognostic value of vascular endothelial growth factor (VEGF)-A and its receptor VEGFR-1 in localized prostate cancer.
Methods: One hundred patients undergoing radical prostatectomy (RP) for clinically localized prostate cancer were prospectively included. Plasma levels of VEGF-A were measured preoperatively. After intervention, tissue microarrays were built from the RP specimens. VEGF-A and VEGFR-1 expressions in prostate cancer tissue were determined using immunochemistry. Then the associations between plasma levels of VEGF-A, VEGF-A and VEGFR-1 expressions in prostate cancer tissue, and the outcome of patients were analyzed.
Results: After a median follow-up of 22 months, 14 patients More >

Bilal Chughtai, Badar M. Mian

Canadian Journal of Urology, Vol.15, No.6, pp. 4375-4380, 2008

Abstract Advances in the early detection and treatment of prostate cancer have progressed far beyond our ability to identify patients with high risk prostate cancer. In general, designation of high risk prostate cancer implies the presence of disease that is likely become progressive or lethal if not managed aggressively. Without proper risk stratifi cation, there is a signifi cant likelihood of both overtreatments of men with low risk disease and undertreatment for men with high risk cancer. The major issues surrounding the clinical management of high risk prostate cancer revolve around the defi nition of high… More >

Shahrokh F. Shariat, Peter T. Scardino, Hans Lilja

Canadian Journal of Urology, Vol.15, No.6, pp. 4363-4374, 2008

Abstract The introduction of total prostate-specifi c antigen (tPSA) testing in serum has revolutionized the detection and management of men with prostate cancer. This review will highlight some of the exciting new developments in the fi eld of prostate cancer screening in general and from our SPORE research program at Memorial-Sloan Kettering Cancer Center. First, it is important to understand that the inherent variability of tPSA levels affects the interpretation of any single results. Total variation in tPSA includes both analytical (i.e., pre-analytical sample handling, laboratory processing, assay performance, and standardization) and biological variation (i.e., metabolism,… More >