Jae Bong Lee¹, Jai Hak Park¹, Sung Ho Lee², Hong-Deok Kim², Han-Sub Chung²

CMES-Computer Modeling in Engineering & Sciences, Vol.11, No.1, pp. 9-16, 2006, DOI:10.3970/cmes.2006.011.009

Abstract The growth of stress corrosion cracks in steam generator tubes is predicted using the Monte Carlo simulation and statistical approaches. The statistical parameters that represent the characteristics of crack growth and crack initiation are derived from in-service inspection (ISI) non-destructive evaluation (NDE) data. Based on the statistical approaches, crack growth models are proposed and applied to predict crack distribution at the end of cycle (EOC). Because in-service inspection (ISI) crack data is different from physical crack data, a simple method for predicting the physical number of cracks from periodic in-service inspection data is proposed in More >

M.H. Djavareshkian¹, M. Khalili²

FDMP-Fluid Dynamics & Materials Processing, Vol.2, No.4, pp. 299-308, 2006, DOI:10.3970/fdmp.2006.002.299

Abstract This paper opens a new horizon on the simulation of sloshing phenomena. One of the most popular Finite Volume methods called VOF (Volume Of Fluid) method is used for tracking the flow in containers. The algorithm is tested for different fluid elevations, physical conditions in different road curves and liquid properties. The method is then validated against an analytical and another numerical solution. These comparisons show that the VOF can effectively solve the sloshing problem for different fluids and a variety of physical and geometrical conditions. More >

Anastasios J. Karayiannakis¹, Byron Asimakopoulos², Anna Efthimiadou², Alexandra K. Tsaroucha¹, Alexandros Polychronidis¹, Constantinos Simopoulos¹

European Cytokine Network, Vol.16, No.1, pp. 91-96, 2005

Abstract We compared serum leptin responses during and after laparoscopic and open cholecystectomy, and assessed their correlation with the responses of inflammatory cytokines. Serum levels of leptin, interleukin-1a (IL-1α), interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-α) were measured by an enzyme-linked immunoassay in 31 patients who underwent laparoscopic cholecystectomy and in 24 patients who underwent open cholecystectomy. Serum samples were obtained preoperatively, at 10 and 30 min after the commencement of surgery, and at 6 and 24 h after the operation. The cumulative responses of leptin, IL-1α, IL-6 and TNF-α to surgery were calculated and the… More >

Sophie G. Fletcher, Dan Theodorescu

Canadian Journal of Urology, Vol.12, Suppl.1, pp. 58-61, 2005

Abstract Introduction: To date, randomized trials comparing radiotherapy to surgery for adenocarcinoma of the prostate are few. Lacking, are randomized comparisons between treatment modalities for the patient with high-risk locally advanced disease. Hence, there is a need to determine which approach offers superior results in these patients who comprise a significant proportion of those dying of prostate cancer. In this short review we highlight key studies that may provide interim answers while awaiting definitive results from randomized studies.
Material and methods: A MEDLINE literature review was performed of studies evaluating current treatment modalities for high-risk (TNM stage >T2b,… More >

Bob Djavan, Shirin Milani, Mesut Remzi

Canadian Journal of Urology, Vol.12, Suppl.1, pp. 44-48, 2005

Abstract Biochemical parameters and pathological features as well as biopsy related morbidity of prostate cancer detected on second, third and fourth repeat prostate biopsy in men with a serum total PSA level between 4 ng/mL and 10 ng/mL were evaluated and compared to those cancers detected on initial prostate biopsy.
In a prospective European Prostate Cancer Detection study, 1051 men with a total PSA level between 4 ng/ mL and 10 ng/mL underwent transrectal ultrasound (TRUS)–guided sextant biopsy and two additional transition zone biopsies. All subjects whose biopsy samples were negative for prostate cancer (CaP) underwent a… More >

Fritz H. Schröder

Canadian Journal of Urology, Vol.12, Suppl.1, pp. 2-6, 2005

Abstract The European Randomized Study of Screening for Prostate Cancer (ERSPC) is a large, randomized controlled trial of screening versus control, conducted in eight European countries (Belgium, Finland, France, Italy, the Netherlands, Spain, Sweden, and Switzerland). This article focuses on important aspects relating to recent findings from the ERSPC about two topics: first, leadtime and overdiagnosis, and second, prostate-specific antigen (PSA) as a test for repeated screening.
The ERSPC together with the prostate cancer arm of the Prostate, Lung, Colon and Ovary (PLCO) screening trial of the National Cancer Institute in the United States are set to… More >

H. Azzouz, J. J. M. C. H. de la Rosette

Canadian Journal of Urology, Vol.12, Suppl.3, pp. 33-37, 2005

Abstract Objective: Different treatment modalities are considered in treating locally advanced prostate cancer in men. This review discusses the long-term follow-up data of patients who underwent radical prostatectomy with or without adjuvant therapy. The value of an (extended) pelvic lymphadenectomy in these patients is also discussed.
Methods: Relevant information was identified through a literature search of published studies and review articles.
Results: Radical prostatectomy alone in locally advanced prostate cancer seems to produce acceptable results. A nerve-preserving procedure in these patients, however, is not an option. Pretreatment with hormonal therapy does not seem to result in prolonged, progression-free or More >

Th. H. Van der Kwast, R. Postma, R. F. Hoedemaeker, G. J. L. H. van Leenders, F. H. Schröder

Canadian Journal of Urology, Vol.12, Suppl.3, pp. 16-20, 2005

Abstract Introduction: Prostate-specific antigen (PSA) testing of asymptomatic men may lead to the detection of "minimal" prostate cancers that are less likely to be associated with morbidity or mortality.
Objective: To examine the significance of various diagnostic outcomes from needle biopsies of the prostate in an asymptomatic population of men.
Methods: Prostatic needle biopsy findings were matched with those from radical prostatectomy specimens using data from the Rotterdam section of the European Randomized study of Screening for Prostate Cancer (ERSPC). Men, aged between 55 and 75 years, with elevated PSA levels underwent lateralized sextant needle biopsies. In corresponding radical… More >

Pierre I. Karakiewicz, Paul Perrotte, Mike McCormack, François Peloquin, Jean-Paul Perreault, Philippe Arjane, Hughes Widmer, Fred Saad

Canadian Journal of Urology, Vol.12, Suppl.3, pp. 5-8, 2005

Abstract Introduction: Prostate biopsy strategies have greatly evolved over the past 2 decades.
Methods: We performed a literature review which addressed the initial and repeat biopsy schemes, pathologic risk factors for a positive repeat biopsy, and the ideal timing as well as the number of repeat biopsy sessions.
Results: Extended biopsy schemes (11-13 cores) should be used at initial and repeat biopsy. In the era of extended biopsy schemes, high-grade prostatic intraepithelial neoplasia no longer represents an independent predictor of prostate cancer on repeat biopsy. Conversely, the risk is appreciably increased with atypical small acinar proliferation, and its presence More >

Mana Al-Assiri, Zorn Kevin, Saleh Binsaleh, Peter T. K. Chan

Canadian Journal of Urology, Vol.12, No.1, pp. 2557-2559, 2005

Abstract Testicular cancer, which generally presents as a scrotal mass of variable sizes, is amongst the most common malignancies in men in the 15- to 35- year age group. A high inguinal orchiectomy is the standard approach for removal of a scrotal mass suspicious of being malignant. A recent report described a combined use of an inguinal incision, for early clamping of the spermatic cord, and a scrotal incision for orchiectomy of a large size testicular seminoma.1 We hereby report a case of a large size testis cancer removed using a single oblique inguinoscrotal incision. This More >