Mingzhu Deng¹, Fang Liu^2,*, Ming Zhao³, Zhiguang Chen², Nong Xiao^2,1

CMC-Computers, Materials & Continua, Vol.58, No.1, pp. 153-167, 2019, DOI:10.32604/cmc.2019.03585

Abstract In the big data era, data unavailability, either temporary or permanent, becomes a normal occurrence on a daily basis. Unlike the permanent data failure, which is fixed through a background job, temporarily unavailable data is recovered on-the-fly to serve the ongoing read request. However, those newly revived data is discarded after serving the request, due to the assumption that data experiencing temporary failures could come back alive later. Such disposal of failure data prevents the sharing of failure information among clients, and leads to many unnecessary data recovery processes, (e.g. caused by either recurring unavailability… More >

Lihua Zhu¹, Yu Wang¹, Lei Wang², Zhiqiang Wu^1,*

CMC-Computers, Materials & Continua, Vol.59, No.3, pp. 1015-1026, 2019, DOI:10.32604/cmc.2019.05656

Abstract The performance of the transfer alignment has great impact on inertial navigation systems. As the transfer alignment is generally implemented using a filter to compensate the errors, its accuracy, rapidity and anti-disturbance capability are key properties to evaluate the filtering process. In terms of the superiority in dealing with the noise, H∞ filtering has been used to improve the anti-disturbance capability of the transfer alignment. However, there is still a need to incorporate system uncertainty due to various dynamic conditions. Based on the structural value theory, a robustness stability analysis method has been proposed for More >

Karen L. Stern, Manoj Monga

Canadian Journal of Urology, Vol.25, No.3, pp. 9313-9316, 2018

Abstract Introduction: The Moses technology of the holmium laser has been shown to decrease retropulsion in the ureter and procedural time in kidney stones during laser lithotripsy. Theoretically, these improvements could lead to cost savings for the patient.
Materials and methods: All patients with total laser energy data recorded who underwent ureteroscopy with laser lithotripsy by a single surgeon at a tertiary care center were included. Total lasing time was calculated from the total laser energy. Sub-analyses were done on stone size and stone composition. The procedure time using Moses technology was projected to be approximately 35% less… More >

Rachel B. Davis, Nicholas J. Farber, Amy Kaplan, Rutveej Patel, Robert E. Steckler, Sammy E. Elsamra

Canadian Journal of Urology, Vol.25, No.4, pp. 9427-9432, 2018

Abstract Introduction: To compare endourology versus pediatric urology exposure to pediatric stone cases during fellowship, comfortability in treating pediatric stone cases, and access to pediatric surgical equipment.
Materials and methods: A survey was distributed to all pediatric urology fellowship programs and the Endourological Society. Age was stratified into < 12 months old, 12 months - 4 years, 5 - 12 years, and 13 - 18 years. Exposure and comfortability performing extracorporeal shock wave lithotripsy (SWL), ureteroscopy (URS), and percutaneous nephrolithotomy (PCNL) were assessed across age groups. Exposure was assessed as “yes/no” and comfortability was scaled from 1-5 (“would… More >

Charlotte K. Roberts¹, Jonathan S. Ellison², Omar Aboumarzouk¹, Mohamed Abd-Alazeez¹, Francis X. Keeley, Jr¹

Canadian Journal of Urology, Vol.25, No.5, pp. 9503-9508, 2018

Abstract Introduction: Renal duplication is a relatively common congenital abnormality of the urinary tract, but symptomatic duplex kidney is a rare presentation in adults. Traditionally, the treatment of choice for poorly functioning moiety has been heminephrectomy. There is extensive literature detailing the outcomes of minimally invasive upper pole heminephrectomy, but comparatively little published regarding lower pole resection, especially in adult patients. We present a series of 13 patients who underwent minimally invasive heminephrectomy for duplex kidney.
Materials and methods: Over a 6-year period (2011-2017), 13 patients at a single center underwent laparoscopic heminephrectomy for symptomatic duplex kidney with… More >

Takeshi Yamasaki, Satoshi Tamada, Minoru Kato, Taiyo Otoshi, Hisao Tanaka, Taro Iguchi, Tatsuya Nakatani

Canadian Journal of Urology, Vol.25, No.6, pp. 9606-9613, 2018

Abstract Introduction: Recently, the use of indocyanine green (ICG) with near infrared fluorescence (NIRF) imaging has emerged as an alternative technique for the real-time delineation of resection margins during partial nephrectomy (PN). We aimed to assess the feasibility of using NIRF imaging with ICG during laparoscopic partial nephrectomy (LPN) to delineate the margin between normal renal parenchyma and renal cortical tumors.
Materials and methods: A retrospective comparison of real-time tumor margin identification and operative outcomes was conducted for 83 patients who underwent LPN with NIRF imaging (IMAGE1 system) and 74 patients who did not.
Results: Tumor margins were identified… More >

Amr Mahran^1,2, Laura Bukavina^1,2, Kirtishri Mishra^1,2, Christina Buzzy^1,2, Morgan L Fish¹, Aidan Bobrow¹, Lee Ponsky^1,2,3

Canadian Journal of Urology, Vol.25, No.6, pp. 9579-9584, 2018

Abstract Introduction: The vast majority of bladder cancer is non-muscle invasive with transurethral resection (TURBT) as the gold standard for surgical treatment. There is a high recurrence of bladder cancer post-surgery, which adds to the frustration in current urologic practice. Current standard of care to further reduce bladder cancer recurrence is instillation of intravesical chemotherapy (ICT), a practice that is not routinely followed. Several studies point to similar effects with normal saline or water irrigation alone. Our objective is to review the current available literature and provide practicing urologists with an alternative to ICT.
Materials and methods: A… More >

Roberta Milani^*, Eleonora Brognara^*, Enrica Fabbri^*, Alessia Finotti^*, Monica Borgatti^*, Ilaria Lampronti^*, Giovanni Marzaro^†, Adriana Chilin^†, Kenneth Ka-Ho Lee^‡, Stanton Hon-Lung Kok^‡, Chung-Hin Chui^§, Roberto Gambari^*

Oncology Research, Vol.26, No.9, pp. 1307-1315, 2018, DOI:10.3727/096504017X14928634401187

Abstract Glioblastoma multiforme (GBM), a malignant tumor of the central nervous system, has a high mortality rate. No curative treatment is presently available, and the most commonly used chemotherapeutic drug, the alkylating agent temozolomide (TMZ), is only able to increase life expectancy and is often associated with drug resistance. Therefore, an urgent need does exist for novel drugs aimed at treating gliomas. In the present study, we obtained three major results using corilagin: (a) demonstrated that it inhibits the growth of U251 glioma cells through activation of the apoptotic pathway; (b) demonstrated that it is also More >

Xinyang Liu^*1, Zhichao Wang^*1, Zongwei Chen^†1, Longzi Liu^*, Lijie Ma^*, Liangqing Dong^*, Zhao Zhang^*, Shu Zhang^*, Liuxiao Yang^*, Jieyi Shi^*, Jia Fan^*‡, Xiaoying Wang^*, Qiang Gao^*‡

Oncology Research, Vol.26, No.2, pp. 231-239, 2018, DOI:10.3727/096504017X15051752095738

Abstract Hepatocellular carcinoma (HCC) is a worldwide health threat with increasing incidence and a high mortality rate. Most HCC patients are diagnosed at an advanced stage and are unable to undergo potential curative surgery. Transcatheter arterial chemoembolization (TACE) and transcatheter arterial chemotherapy infusion (TACI) are two of the main palliative treatments for advanced HCC patients. The clinical efficacy and safety of TACE and TACI are controversial. For this reason, we conducted a systematic review and meta-analysis to summarize the current evidence. We searched for randomized controlled trials (RCTs) and cohort studies that compared the clinical outcomes… More >

Vinitha Richard, Rajesh Raju, Aswathy Mary Paul, Reshmi Girijadevi, Thankayyan Retnabai Santhosh Kumar, Madhavan Radhakrishna Pillai

Oncology Research, Vol.26, No.1, pp. 17-26, 2018, DOI:10.3727/096504017X14881490607028

Abstract This study is an integrated analysis of the transcriptome profile microRNA (miRNA) and its experimentally validated mRNA targets differentially expressed in the tumorigenic stem-like fraction of oral squamous cell carcinoma (OSCC). We had previously reported the coexistence of multiple drug-resistant tumorigenic fractions, termed side population (SP1, SP2, and MP2), and a nontumorigenic fraction, termed main population (MP1), in oral cancer. These fractions displayed a self-renewal, regenerative potential and expressed known stemness-related cell surface markers despite functional differences. Flow cytometrically sorted pure fractions of SP1 and MP1 cells were subjected to differential expression analysis of both… More >