Yun Peng¹, Guoan Li^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 128-129, 2019, DOI:10.32604/mcb.2019.07392

Abstract This article has no abstract. More >

Nathaniel Huebsch^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 107-108, 2019, DOI:10.32604/mcb.2019.08524

Abstract This article has no abstract. More >

Jiachen Wei^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 103-104, 2019, DOI:10.32604/mcb.2019.07721

Abstract Phoretic flow can be generated by different types of gradient (e.g. temperature, concentration, or charge gradient) [1-3]. Within micro-to-nano confined system, the diffusio-phoretic property for proteins differs dramatically from that obtained in bulk condition, due to concentration fluctuation that emerges at microscopic level induced by specific and nonspecific interactions between protein and co-solute [4-5]. The phoretic mobility of protein individuals and complex in solute gradients can be theoretically described by continuum model [1-2] that neglects microscopic heterogeneity and determined experimentally by microfluidics [6], but the underlying mechanism of diffusio-phoretic motion for confined protein still remains… More >

Ning Jiang^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 102-102, 2019, DOI:10.32604/mcb.2019.07486

Abstract Force is not only involved in motion, but also involved in molecular interactions that guide cells to execute important physiological functions. Getting to know Dr. Fung at an early age shaped my college major decision, which lead me into the field of biomedical engineering. Applying a force-based measurement tool to study T cell receptor interaction with ligands in graduate school prepared me to use technology development as a foundation to answer important biological and clinical questions.
By combining engineering principle, quantitative modeling, and a deep understanding of biology and medicine, my current research focuses in… More >

Yuhsuan Wang^1,2, Yuwei Guo^1,2, Lisha Zheng^1,2,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 99-99, 2019, DOI:10.32604/mcb.2019.06995

Abstract Many studies have shown that cell shape effects cell chromatin aggregation, gene expression, protein synthesis, cell growth, apoptosis, and cytoskeletal rearrangement [1, 2]. Dental pulp stem cells (DPSCs) are capable of osteogenic, dentinogenic, chondrogenic, and neurogenic differentiation. They are regarded as a promising candidate for tissue regeneration. How the cell shape regulates their cell behavior is still unknown. We used micropatterning technology to design single cell patterns in a 1:1, 1:2, 1:4, 1:8, 1:16 length-width ratio of rectangles with the same area. The results indicated that cell shape rearranged the cytoskeleton of DPSCs. The nuclear… More >

Lili Dong¹, Yang Song^1,*, Li Yang^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 78-78, 2019, DOI:10.32604/mcb.2019.07130

Abstract It has been widely recognized that stem cells possess the potential of osteogenic differentiation, which greatly contribute to bone repair. Recently, accumulating evidences have indicated that mechanical cues are required for bone repair ^[1,2]. However, how local and recruited stem cells in the bone architecture receive the mechanical signals is poorly understood ^[3,4]. The purpose of this study is to demonstrate that macrophages potentially transduce the mechanical signals for stem cell osteogenic lineage. This demonstration has been carried out through a co-culture system to investigate the effect of macrophages which subjected to cyclic stretch on the… More >

Kerlin P. Robert¹, Jiaoyan Li², James D. Lee^1,*

Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 74-74, 2019, DOI:10.32604/mcb.2019.07125

Abstract This presentation focuses on the new and upcoming concept of 4D printing and its vast scope and importance in the research and development in industry. The 3D printing object is considered as a layered structure. Each layer may have different orientation. Therefore each layer may behave differently under the change of its environment. We formulate the theoretical shape changing process of 4D printing resulted from (I) the biological growth or swelling, (II) the change of temperature, and (III) the effect of electric field on piezoelectric material of the 3D printing product. Then we illustrate this More >

Philip M. Tan¹, Kyle S. Buchholz², Shulin Cao², Yasser Aboelkassem², Jeffrey H. Omens², Andrew D. McCulloch^2,*, Jeffrey J. Saucerman¹

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 1-3, 2019, DOI:10.32604/mcb.2019.05693

Abstract In this article, we summarize our systems model of cardiomyocyte mechano-signaling published in PLoS Computational Biology and discuss new approaches to extending these models to predict cardiac myocyte gene expression in response to stretch. More >

Zhiyong Li^1,2,*, Dalin Tang^1,3

Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 1-7, 2019, DOI:10.32604/mcb.2019.05830

Abstract Cardiovascular disease remains as the leading cause of death worldwide, and the technologies developed by different groups need to be communicated and shared with all related research communities for a boarder implementation. Challenges in imaging technology, mathematical modelling, material description, mechanical representation, disease progression, prediction methods, and final transition to clinical applications are calling for collaborative effort of the entire research community to act together and bring research effort closer to actual clinical applications. Researchers from different disciplines need to reach out to share their expertise, as well as to listen to other people to More >

Surkay D. Akbarov^1,2,*, Emin T. Bagirov²

CMES-Computer Modeling in Engineering & Sciences, Vol.121, No.1, pp. 315-348, 2019, DOI:10.32604/cmes.2019.07732

Abstract The paper deals with the study of the influence of the non-homogeneous pre-stresses in the system consisting of the hollow cylinder and surrounding elastic medium on the frequency response of this system caused by the time-harmonic ring load acting in the interior of the cylinder. The axisymmetric problem is considered and it is assumed that in the initial state, the system is compressed in the radial direction with homogeneously distributed static forces as a result of which, non-homogeneous pre-stresses (or initial stresses) appear in that. It is also assumed that after these pre-stresses appear in… More >