M.El-Gammal¹, J.M.Floryan¹

FDMP-Fluid Dynamics & Materials Processing, Vol.2, No.1, pp. 17-26, 2006, DOI:10.3970/fdmp.2006.002.017

Abstract Interface deformation and thermocapillary rupture in a cavity with free upper surface subject to concentrated heating from above is investigated. The dynamics of the process is modulated by placing different amounts of liquid in the cavity. The results determined for large Biot and zero Marangoni numbers show the existence of limit points beyond which steady, continuous interface cannot exist and processes leading to the interface rupture develop. Evolution of the limit point as a function of the mass of the liquid is investigated. The topology of the flow field is found to be qualitatively similar, More >

B.B. Karki¹, D. Bhattarai¹, L. Stixrude²

CMC-Computers, Materials & Continua, Vol.3, No.3, pp. 107-118, 2006, DOI:10.3970/cmc.2006.003.107

Abstract Computer modeling of liquid phase poses tremendous challenge: It requires a relatively large simulation size, long simulation time and accurate interatomic interaction and as such, it produces massive amounts of data. Recent advances in hardware and software have made it possible to accurately simulate the liquid phase. This paper reports the details of methodology used in the context of liquid simulations and subsequent analysis of the output data. For illustration purpose, we consider the results for the liquid phases of two geophysically relevant materials, namely MgO and MgSiO₃. The simulations are performed using the parallel first-principles More >

Sara Pagani, Cristina Meazza, Paola Travaglino, Antonia Moretta, Mauro Bozzola

European Cytokine Network, Vol.16, No.1, pp. 65-69, 2005

Abstract The aim of the present study was to establish whether growth hormone (GH) treatment in vivo affects pro-inflammatory cytokine production by resting or in vitro, activated, cultured, peripheral blood mononuclear cells (PBMC) from children with complete growth hormone deficiency (GHD). We evaluated 11, pre-pubertal children (6 males and 5 females) with GHD, aged between 6 and 14 years, and 9, age- and sex-matched healthy subjects were studied as controls (CTRLs). Freshly isolated PBMC were cultured for 4 or 24 h in X-VIVO medium in the presence or absence of 0.01 lg/mL lipopolysaccharide for the determination… More >

Othmar Ludwiczek¹, Arthur Kaser¹, Daniela Novick², Charles A. Dinarello³, Menachem Rubinstein², Herbert Tilg^1,4

European Cytokine Network, Vol.16, No.1, pp. 27-33, 2005

Abstract Objectives. Interleukin 18 (IL-18) is a proinflammatory cytokine and a member of the IL-1 family. Animal models and investigations in humans point to an important role for this cytokine in inflammatory bowel diseases (IBD). IL-18 binding protein (IL-18BP) is a naturally occurring antagonist of IL-18. Methods. In this study, we measured IL-18 and IL-18BP plasma concentrations and spontaneous release in cultures of colonic explants from healthy subjects (n = 41), patients with Crohn’s disease (CD, n = 135), and patients with ulcerative colitis (UC, n = 93). Results. Both CD and UC patients had higher… More >

Mahmoud Abu Elhija¹, Hadas Potashnik¹, Eitan Lunenfeld², Gad Potashnik², Stefan Schlatt³, Eberhard Nieschlag⁴, Mahmoud Huleihel¹

European Cytokine Network, Vol.16, No.2, pp. 167-172, 2005

Abstract Spermatogenesis is a highly controlled process of proliferation, meiosis, and differentiation. Systemic infection and chronic inflammation can impair testicular steroidogenesis and spermatogenesis. In this study, we examined the effect of systemic infection – intraperitoneal (i.p.) injection of lipopolysaccharide (LPS) – on the expression levels of IL-6 in the testis of sexually immature and adult mice. IL-6 levels in testicular homogenates of immature mice were significantly higher than in mature mice (both protein and RNA levels), before and after LPS injection. Injection of LPS (i.p.) into mature mice over 3 hours, significantly increased testicular IL-6 protein… More >

F. Hérodin, P. Thullier, D. Garin, M. Drouet

European Cytokine Network, Vol.16, No.2, pp. 104-116, 2005

Abstract Nonhuman primates have been used for biomedical research for several decades. They have proved to be models that are relevant to humans because of the high level of gene homology which underlies physiological and biochemical similarities. The similarity of monkeys to humans has been used to investigate pathophysiological mechanisms in hematology, immunology and virology. New therapeutic procedures can be assessed in primates by using materials, in particular pharmacological reagents, and methods designed for humans. The relevance of these models also relies on the use of species-specific pathogens and the availability of recombinant, homologous cytokines. The… More >

Pierre I. Karakiewicz, Paul Perrotte, Mike McCormack, François Peloquin, Jean-Paul Perreault, Philippe Arjane, Hughes Widmer, Fred Saad

Canadian Journal of Urology, Vol.12, Suppl.3, pp. 5-8, 2005

Abstract Introduction: Prostate biopsy strategies have greatly evolved over the past 2 decades.
Methods: We performed a literature review which addressed the initial and repeat biopsy schemes, pathologic risk factors for a positive repeat biopsy, and the ideal timing as well as the number of repeat biopsy sessions.
Results: Extended biopsy schemes (11-13 cores) should be used at initial and repeat biopsy. In the era of extended biopsy schemes, high-grade prostatic intraepithelial neoplasia no longer represents an independent predictor of prostate cancer on repeat biopsy. Conversely, the risk is appreciably increased with atypical small acinar proliferation, and its presence More >

Saleh Binsaleh, Roman Jednak, Joao Luiz Pippi-Salle

Canadian Journal of Urology, Vol.12, No.3, pp. 2724-2725, 2005

Abstract We report the case of a neonate who underwent bladder exstrophy repair on the second day of life. Bilateral ureteral stents were placed intraoperatively. Postoperatively azotemia developed secondary to kinking of the proximal ureter bilaterally. Issues in diagnosis and management are discussed. More >

Howard H. Pai^1,2, Francis Lau²

Canadian Journal of Urology, Vol.12, No.3, pp. 2700-2709, 2005

Abstract Introduction: Providing men with prostate cancer (MPC) timely access to their health records and information (HRI) can enhance their ability to understand their condition and engage in shared medical decision making with their health care provider (HCP). The Internet is a potential means of enhancing such interactions.
Materials and methods: Two surveys were conducted at a PC support group in Victoria, BC to identify the health information needs of MPC and the ability to access their HRI. Another objective was to identify the potential role of web-enabled HRI systems at meeting these needs. Sixty-one participants (41 men… More >

CARLOS A. BUSSO*, BARRY L. PERRYMAN**

BIOCELL, Vol.29, No.3, pp. 279-285, 2005, DOI:10.32604/biocell.2005.29.279

Abstract Seed size is a crucial plant trait that may potentially affect not only immediate seedling success but also the subsequent generation. We examined variation in seed weight of Wyoming sagebrush (Artemisia tridentata ssp. wyomingensis Beetle and Young), an excellent candidate species for rangeland restoration. The working hypothesis was that a major fraction of spatial and temporal variability in seed size (weight) of Wyoming sagebrush could be explained by variations in mean monthly temperatures and precipitation. Seed collection was conducted at Battle Mountain and Eden Valley sites in northern Nevada, USA, during November of 2002 and 2003. Frequency… More >