Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (2,701)
  • Open Access

    ABSTRACT

    Immune Cells Migrating through the Brain Endothelia Junctions Served as Shuttles for Nanoparticles Delivery to Glioblastoma

    Gloria B. Kim1,†, Qiong Wei2,†, Virginia Aragon-Sanabria1, Sulin Zhang2, Jian Yang1, Cheng Dong1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 15-15, 2019, DOI:10.32604/mcb.2019.07137

    Abstract Most cells survive and grow by attaching and spreading on a substrate. They generate internal tension that contracts the cell body and thus exert tractions on the underlying substrate through focal adhesions. Traction force also plays a critical role in many biological processes, such as inflammation, metastasis, and angiogenesis. Thus, measuring the cell traction force provides valuable information on understanding the underlying mechanism of these biological processes. Here, a traction force microscopy (TFM) method using super thin hydrogels composed of immobilized fluorescent beads was utilized to quantify the mechanical forces generated during the transmigration of… More >

  • Open Access

    ABSTRACT

    Autodigestion in Physiological Shock, Organ Dysfunction and Death

    Erik B. Kistler1, Geert W. Schmid-Schönbein2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 8-8, 2019, DOI:10.32604/mcb.2019.07256

    Abstract A longstanding question in research on organ failure after physiological shock (such as trauma, burns, sepsis, surgery and medical emergencies) is the underlying mechanism for a progressive loss of cell and tissue functions. Our systematic analysis of this problem has served to identify digestive enzymes as key players [1, 2]. After synthesis and discharge from the pancreas, the digestive enzymes are usually contained inside the lumen of the small intestine where they break down food every day. Escape of the digestive enzymes out of the lumen of the intestine is kept to a minimum by… More >

  • Open Access

    ABSTRACT

    Mechanical Characterization and Constitutive Modeling of Rabbit Aortas in Health and Diabetes

    Zhi Zhang1, Jianhua Tong1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 43-43, 2019, DOI:10.32604/mcb.2019.05721

    Abstract Diabetes is a major risk factor to cause macrovascular diseases and plays a pivotal role in aortic wall remodeling. However, the effects of diabetes on elastic properties of aortas remain largely unknown. Thirty adult rabbits (1.6-2.2 kg) were collected and the type I diabetic rabbit model was induced by injection of alloxan. A total of 15 control and 15 diabetic rabbit (abdominal) aortas were harvested. Uniaxial and biaxial tensile tests were performed to measure ultimate tensile strength and to characterize biaxial mechanical behaviors of the aortas. A material model was fitted to the biaxial experimental… More >

  • Open Access

    ABSTRACT

    TET1 Alternative Isoform Regulates Oscillatory Shear Stress Induced Endothelial Dysfunction

    Lu Huang1, Juhui Qiu1,*, Guixue Wang1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 33-34, 2019, DOI:10.32604/mcb.2019.05714

    Abstract Oscillatory shear stress (OSS) is one of the major risk factors related to endothelial (EC) dysfunction, which contributes to atherosclerosis. Our previous study indicated that inhibitor of DNA binding 1 (Id1) plays vital role in the regulation of OSS mediated EC function related to atherosclerosis. However, the initiation mechanism during this process remains to be elucidated. Ten-eleven Translocation protein 1 alternative isoform (Tet1s) is a newly reported protein that may have function in adult tissue. Here, we investigate the role of Tet1s in regulating OSS mediated endothelial dysfunction and its underlying mechanism. First, physical interaction… More >

  • Open Access

    ARTICLE

    Material Selection of a Natural Fibre Reinforced Polymer Composites using an Analytical Approach

    M. Noryani1, 3, 5, S. M. Sapuan1, 2,*, M. T. Mastura4, 5, M. Y. M. Zuhri1, E. S. Zainudin1

    Journal of Renewable Materials, Vol.7, No.11, pp. 1165-1179, 2019, DOI:10.32604/jrm.2019.07691 - 14 July 2021

    Abstract Material selection has become a critical part of design for engineers, due to availability of diverse choice of materials that have similar properties and meet the product design specification. Implementation of statistical analysis alone makes it difficult to identify the ideal composition of the final composite. An integrated approach between statistical model and micromechanical model is desired. In this paper, resultant natural fibre and polymer matrix from previous study is used to estimate the mechanical properties such as density, Young’s modulus and tensile strength. Four levels of fibre loading are used to compare the optimum More >

  • Open Access

    ARTICLE

    Mechanical Properties of a Eucalyptus-Based Oriented Oblique Strand Lumber for Structural Applications

    Jiawei Chen1, Haibei Xiong1,*, Zhifang Wang1, Linqing Yang2

    Journal of Renewable Materials, Vol.7, No.11, pp. 1147-1164, 2019, DOI:10.32604/jrm.2019.07642

    Abstract Wood and wood-based composite materials have gained increasing attention in the sustainable building industry because of their renewability and environmental friendliness. Oriented oblique strand lumber (Eucalyptus Strand Wood, ESWood), which is manufactured from fast-growing small diameter eucalyptus wood (Eucalyptus urophylla × E. grandis), is introduced in this paper. Small clear specimen tests were conducted to determine the mechanical properties of ESWood material while full-scale component tests were performed to observe the structural performance of ESWood beams. A comparison of mechanical properties of ESWood with other wood/bamboo-based materials is then reported. From the results presented herein,… More >

  • Open Access

    ARTICLE

    Development of Biocomposites of MCC Extracted From Non-Wood Sources

    T. Dipin1, T. V. Jinitha1, E. Purushothaman1,*

    Journal of Renewable Materials, Vol.7, No.11, pp. 1109-1119, 2019, DOI:10.32604/jrm.2019.07636 - 14 July 2021

    Abstract The present work mainly focuses on the estimation of various components and the extraction of microcrystalline cellulose (MCC) from non- wood sources like Country Almond/Badam shell through acid hydrolysis. This hydrolyzed MCC was successfully used as reinforcement for development of biocomposites. Country Almond/Badam trees are found all over Kerala, India and they give nuts once in a year. Usually the nut shells are discarded and are becoming one of the sources of agricultural waste. During this investigation various components were isolated from the Country Almond shells and they were characterised using different spectral and analytical… More >

  • Open Access

    ARTICLE

    Biocomposites Based on Thermoplastic Starch and Granite Sand Quarry Waste

    María G. Passaretti1,2,*, Mario D. Ninago3,4, Cecilia I. Paulo5, Horacio A. Petit5, Edgardo F. Irassarc5, Daniel A. Vega6, Marcelo A. Villar1,2, Olivia V. López1

    Journal of Renewable Materials, Vol.7, No.4, pp. 393-402, 2019, DOI:10.32604/jrm.2019.04281

    Abstract Granite stone is a by-product of the rock crushing manufacturing. An industrial waste in powder form that causes health problems and environmental pollution. Fine particles fraction can be used as a partial replacement of sand in concrete manufacture. In this work, an alternative exploitation of this waste fraction is proposed. Granite sand (GS) with particles mean size of ~1 μm was employed as thermoplastic starch (TPS) filler at different concentrations. Biocomposites were obtained by melt-mixing and thermo-compression, achieving translucent and easy to handle films. A good GS dispersion within the matrix was evidenced by SEM. More >

  • Open Access

    ARTICLE

    Experimental and Numerical Investigation on the External Aerodynamic Noise of High-Speed Train

    Shijie Jiang*, Song Yang, Bohong Zhang, Bangchun Wen

    Sound & Vibration, Vol.53, No.4, pp. 129-138, 2019, DOI:10.32604/sv.2019.04048

    Abstract Aerodynamic noise is the dominant noise source of the high-speed train. It not only seriously affects the passenger comfort and people’s normal life along the railway line, but also may cause fatigue damage to the surrounding equipment and buildings. This manuscript carried out the simulation and experimental study on the external aerodynamic noise of high-speed train, in order to increase the understanding of the noise and hence to be better able to control it. The on-line tests were performed to verify that it is reasonable to simplify the high-speed train model. The turbulent air flow… More >

  • Open Access

    ARTICLE

    SPAG9 promotes prostate cancer growth and metastasis

    Chunhua YANG1,2,3, Ye TIAN1,2,3

    BIOCELL, Vol.43, No.3, pp. 207-214, 2019, DOI:10.32604/biocell.2019.07258

    Abstract Sperm-associated antigen 9 (SPAG9) expression is increased in prostate tissues of prostate cancer patients. This experimental study aimed to investigate the role of SPAG9 in bone metastasis of prostate cancer. Immunohistochemical analysis showed that SPAG9 staining was positive in 81.67% of 240 cases of prostatic carcinoma but only in 6.67% of 120 cases of benign prostate hyperplasia. Strong PAG9 staining was positively correlated with Gleason score and bone metastasis in 240 prostate cancer patients (p < 0.05), but not with the age or serum prostatespecific antigen level (p > 0.05). PC-3 cells were transfected with shRNA… More >

Displaying 1751-1760 on page 176 of 2701. Per Page