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  • Open Access

    REVIEW

    Oxidative effects of the harmful algal blooms on primary organisms of the food web

    Joaquin Cabrera1,2, Paula Mariela González1,2, Susana Puntarulo1,2

    BIOCELL, Vol.43, No.2, pp. 41-50, 2019, DOI:10.32604/biocell.2019.06163

    Abstract Degraded water quality from nutrient pollution, physical, biological, and other chemical factors contributes to the development and persistence of many harmful algal blooms (HABs). The complex dynamics of the HABs is a challenge to marine ecosystems for the toxic effects reported. The consequences include fish, bird, and mammal mortality, respiratory or digestive tract problems, memory loss, seizures, lesions and skin irritation in many organisms. This review is intended to briefly summarize the recent reported information on harmful marine toxin deleterious effects over the primary organisms of the food web, namely algae, zooplankton and invertebrates.… More >

  • Open Access

    ARTICLE

    Alteration of ADP-ribosylation in aging rat brain astrocytes

    Manoochehr MESSRIPOUR1, Azadeh MESRIPOUR2

    BIOCELL, Vol.43, No.1, pp. 37-40, 2019, DOI:10.32604/biocell.2019.05865

    Abstract DNA damage and the enzyme poly (ADP-ribose) polymerase (PARP) associated with the pathogenesis of numerous age-related neurodegenerative disorders. Astrocytes play crucial roles in both support metabolic functions and cell viability of the brain. PARP regulates DNA damage and repair in the brain cells. In this study PARP activity and DNA strand break were investigated in the astrocytes isolated from young and aged rat brain. Three and 30-month-old rats were killed by decapitation and brains were removed onto an ice cooled glass plate. Astrocytes were isolated by sucrose density gradient centrifugation and glutamine synthetase (GS) served… More >

  • Open Access

    ARTICLE

    Design and development of a dual-flow bioreactor mimicking intestinal peristalsis and permeability in epithelial tissue barriers for drug transport assessment

    Odin RAMÍREZ-FERNÁNDEZ1,2,3,*, Ludovika CACOPARDO1, Benjamín LEON-MANCILLA2, Joana COSTA1

    BIOCELL, Vol.43, No.1, pp. 29-36, 2019, DOI:10.32604/biocell.2019.04790

    Abstract We present a bioreactor system which combines a semi permeable membrane that simulates the osmotic nutrients interchange in the small intestine circulation and rhythmic peristaltic movement. This custom-designed presents a semipermeable membrane bioreactor, with peristaltic flow and compression variation that allows adjustment of luminal flow rate. In addition, this system is also capable of achieving the drug distribution in the small intestine model from the apical compartment to the basal compartment by the semipermeable channel. This dynamic bioreactor can mimic the human small intestine with increased accuracy to overcome many of the limitations and accuracy More >

  • Open Access

    ARTICLE

    Mesenchymal stem cells transplantation attenuates experimentally induced brain injury after neonatal hypoxia by different two routes of administrations

    Nesrine EBRAHIM1, Eman EHSAN2, Eman Abd EL GHANY2, Dina SABRY3, Ashraf SHAMAA4

    BIOCELL, Vol.43, No.1, pp. 21-28, 2019, DOI:10.32604/biocell.2019.06111

    Abstract The neonatal hypoxic–ischemic encephalopathy (HIE) is an important cause of neurological morbidity and mortality in neonates. Cell therapy is considered a promising method for treating severe neurological disorders such as this one. Stem cells have the capacity for self-renewal and differentiation into certain cell lineages. The present study was aimed to find out the most beneficial route of bone marrow-derived mesenchymal stem cells (BMSCs) administration for the attenuation of experimentally induced HIE in neonatal rats. Sixty neonatal rats were divided randomly into four groups. Group 1: control group. Group 2: rats were exposed to… More >

  • Open Access

    ABSTRACT

    DIC Measurement of Deformation in Cracked CFRP Cross-Ply Laminates

    M. J. Mohammad Fikry1,*,Shinji Ogihara1, Vladimir Vinogradov2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.22, No.4, pp. 172-172, 2019, DOI:10.32604/icces.2019.5210

    Abstract Digital Image Correlation (DIC) is a new non-contact method to analyze the deformation of materials that can measure displacement or strain behavior during tensile loading. In this study, DIC is used to measure the deformation of cross-ply Carbon Fibre Reinforced Plastics (CFRP) laminates and for the detection of damages in them. The objective of this study is to measure the deformation around the damages in cross-ply CFRP laminates by using the DIC system from both width and thickness directions. For this purpose, thick CFRP [04/9024]s and thinner [0/906]s laminates were tested. In cross-ply laminates, usually a… More >

  • Open Access

    ABSTRACT

    The Experimental Simulation Technology and System of Solid Fluidization Exploitation of Marine Non-Diagenetic Natural Gas Hydrate

    Lin Jiang1,*, Na Wei1,*, Jinzhou Zhao1, Shouwei Zhou1,2, Liehui Zhang1, Qingping Li3, Guorong Wang1, Jun Zhao1, Kaisong Wu1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.4, pp. 81-83, 2019, DOI:10.32604/icces.2019.04515

    Abstract With huge reserves, marine natural gas hydrate is one of the most potential unconventional alternative energy sources after shale gas, coalbed methane and tight gas. The research and pilot engineering of natural gas hydrate exploitation technology mainly adopts the depressurization method at home and abroad, all of which refer to the exploitation technology of conventional oil and gas.
    While using the depressurization method to exploit the non-diagenetic gas hydrate, the undersea hydrate decomposes in situ, partly flows to the bottom of the well, and escapes into the seawater in large quantities, and the hydrate will face… More >

  • Open Access

    ABSTRACT

    Computational Grains for Nanocomposites with Interface Stress Effects

    Junbo Wang*, Leiting Dong

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.4, pp. 75-75, 2019, DOI:10.32604/icces.2019.04820

    Abstract In this study, two/three-dimensional computational grains are developed for micromechanical modeling of heterogeneous materials with nanoscale inhomogeneities, considering the interface stress effect. Two types of computational grains are developed, depending on the types of inhomogeneity in each element. Each computational grain can include alternatively a spherical void or a spherical elastic inclusion. In these computational grains, an inter-element compatible displacement field is assumed along the element outer-boundary, and interior displacement fields in the matrix as well as in the inclusion are independently assumed as T-Trefftz trial functions. For planar problems, complex potentials are used to… More >

  • Open Access

    ABSTRACT

    Solutions of Nonlinear Bending Problems of Plates with Complex Shapes

    Jizeng Wang*, Cong Xu, Youhe Zhou

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.22, No.1, pp. 114-114, 2019, DOI:10.32604/icces.2019.05298

    Abstract A high-order wavelet method is developed for general nonlinear boundary value problems with complex boundaries in mechanics. This method is established based on wavelet approximation of multiple integrals of interval bounded functions combined with an accurate and adjustable boundary extension technique. The convergence order of this approximation has been proven to be N as long as a typical family of wavelets named Coiflets with N-1 vanishing moment are adopted, which can be any positive even integers. Error analysis has proven that the proposed method is in accuracy of order N, and condition numbers of relevant More >

  • Open Access

    ABSTRACT

    The Influence of Initial Deflection on Nonlinear Flutter Response of Functionally Graded Plates

    Wei Xia1,2,*, Kun Wang1, Haitao Yang1, Shengping Shen1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.21, No.2, pp. 27-27, 2019, DOI:10.32604/icces.2019.05197

    Abstract Panel flutter arises from the aeroelastic instability of the skin structures on the high-speed vehicles, usually in supersonic regime and combined with thermal environment. Unlike the catastrophic flutter of the wings, panel flutter tends to be treated as non-catastrophic one. The nonlinear panel flutter response is of great interest to find the fatigue loading spectra. Present work introduces an aeroelastic model for a thermal isolating panel made from functionally graded materials (FGMs). The Mindlin plate theory is employed to establish the structural equations, the first-order piston theory is adopted for the supersonic aerodynamic loads, and… More >

  • Open Access

    ARTICLE

    Mechanical Properties of Polypropylene Composites Reinforced with Macadamia Nutshell Fibers

    Joyce de P. Cipriano2, N. C. Zanini1, I. R. Dantas1, D. R. Mulinari1,*

    Journal of Renewable Materials, Vol.7, No.10, pp. 1047-1053, 2019, DOI:10.32604/jrm.2019.00001

    Abstract The use of natural fibers as an additive in polymeric matrices has attracted interest of the automotive industries, for its low cost, mechanical properties, biodegradability and lightness. However, the hydrophilic nature of the fiber makes polymer compatibility difficult. Fiber surface treatments can be used to enhance the fiber/matrix interface. In the present work, polypropylene (PP) composites reinforced with fibers from macadamia nutshell were obtained and characterized. Macadamia nutshell fibers were treated by an alkaline treatment with sodium hydroxide (NaOH 4%) to improve adhesion between fibers and matrix. Fibers were characterized by techniques of Scanning Electron More >

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