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  • Open Access

    RESIDENT’S CORNER

    Transperitoneal laparoscopic radical nephrectomy after multiple previous abdominal surgeries and intraperitoneal hyperthermic chemotherapy: a case report

    Yves Collin1, Anne Méziat-Burdin2, Robert Sabbagh3

    Canadian Journal of Urology, Vol.19, No.2, pp. 6204-6206, 2012

    Abstract Laparoscopic indications are still growing due to the acquisition and development of new skills and expertise in the laparoscopic field. We report the first case of a successful transperitoneal right radical nephrectomy after intraperitoneal hyperthermic chemotherapy in a 56-year-old female who previously underwent multiple abdominal surgeries for appendicular adenocarcinoma with pseudomyxoma peritonei. In patients with multiples previous abdominal surgeries and intraperitoneal chemotherapy, transperitoneal laparoscopic surgeries are feasible in experienced hands. However, patient safety is paramount and conversion to open surgery should always be considered in case of complications. More >

  • Open Access

    RESIDENT’S CORNER

    Large teratoma at aortic bifurcation: an unusual metastasis of testicular cancer

    Yachao Zhang, Timothy Byler, Steve Landas, Margaret Ekroth, Oleg Shapiro

    Canadian Journal of Urology, Vol.19, No.2, pp. 6201-6203, 2012

    Abstract A 29-year-old man presented with a right testicular mass. Serum tumor markers were within normal limits. When compared to a previous computed tomography (CT) scan, a new 4 cm presacral mass was present. He underwent radical right inguinal orchiectomy that demonstrated a mature teratoma and seminomatous components. The patient received four cycles of chemotherapy. Over the courseofchemotherapy,themassgrewinsizeandtherefore he underwent retroperitoneal lymph node dissection. Pathology confrmed it to be a teratoma with negative retroperitoneal lymph nodes. The unusual presentation of an isolated metastasis to the presacral region raises the question of altered lymphatic drainage. More >

  • Open Access

    HOW I DO IT

    Acritical appraisal of accuracy and cost of laboratory methodologies for the diagnosis of hypogonadism: the role of free testosterone assays

    Alvaro Morales, Christine P. Collier, Albert F. Clark

    Canadian Journal of Urology, Vol.19, No.3, pp. 6314-6318, 2012

    Abstract The biochemical diagnosis of male hypogonadism remains a controversial issue. The problem is compounded by the variety of laboratory assays available to measure serum testosterone (T) and the limited understanding, among clinicians, of their relative diagnostic validity. It is widely accepted that only the testosterone not bound to sex hormone-binding globulin is metabolically active. Therefore, for diagnostic purposes, it is common practice to order the measurement of free T (FT) or bioavailable T (BAT).
    Our objective is to describe the methods available for measuring FT and to review the literature to determine the relevance of… More >

  • Open Access

    EDITORIAL COMMENT

    Alvimopan provides rapid gastrointestinal recovery without nasogastric tube decompression after radical cystectomy and urinary diversion

    William C. Huang

    Canadian Journal of Urology, Vol.19, No.3, pp. 6298-6298, 2012

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Alvimopan provides rapid gastrointestinal recovery without nasogastric tube decompression after radical cystectomy and urinary diversion

    Anup A. Vora, Andrew Harbin, Robert Rayson, Keith Christiansen, Reza Ghasemian, Jonathan Hwang, Mohan Verghese

    Canadian Journal of Urology, Vol.19, No.3, pp. 6293-6298, 2012

    Abstract Introduction: Radical cystectomy is associated with significant morbidity, with rates of gastrointestinal complications as high as 30%. Alvimopan is a mu opioid receptor antagonist that has been shown in randomized control trials to accelerate gastrointestinal recovery in patients undergoing bowel resection with primary anastamosis. We report our experience with gastrointestinal recovery for patients undergoing cystectomy with urinary diversion treated with alvimopan.
    Materials and methods: Between January 2008 and August 2011, 50 consecutive patients underwent radical cystectomy with urinary diversion at our institution. The first 27 patients in our study did not receive alvimopan preoperatively. The latter 23… More >

  • Open Access

    ARTICLE

    Positive effects of zoledronate on skeletal-related events in patients with renal cell cancer and bone metastases

    Ulf W. Tunn1, Amulf Stenzl2, Wolfgang Schultze-Seemann3, Arne Strauss4, Manfred Kindler5, Kurt Miller6, Manfred P. Wirth7, Niko Zantl8, Matthias Schulze9, Christoph May10, Amelie Ruebel10, Katrin Birkholz10, Viktor Gruenwald11

    Canadian Journal of Urology, Vol.19, No.3, pp. 6261-6267, 2012

    Abstract Introduction: Approximately 30% of patients with renal cell cancer (RCC) develop bone metastasis, causing skeletal-related events (SREs): pathologic fracture, spinal cord compression, surgery to bone, and radiotherapy. Zoledronic acid demonstrated significant clinical benefit in RCC patients in a retrospective analysis. The primary objective of this prospective study was to evaluate the proportion of patients experiencing ≥ 1 SRE during 12 months of zoledronic acid treatment and to verify the retrospective data.
    Materials and methods: Fifty patients with histologically confirmed RCC and evidence of ≥ 1 cancer-related bone lesion, and ≤ 3 prior bisphosphonate applications were enrolled across… More >

  • Open Access

    ARTICLE

    Lymphangiography with sclerotherapy: a novel therapy for refractory chylous ascites

    Jeffrey K. Mullins, Phillip M. Pierorazio, Elias S. Hyams, Sally E. Mitchell, Mohamad E. Allaf

    Canadian Journal of Urology, Vol.19, No.3, pp. 6250-6254, 2012

    Abstract Introduction: We report the outcomes of a small series of patients with refractory chylous ascites following urologic surgery treated with lymphangiography +/- sclerotherapy.
    Materials and methods: Retrospective review revealed three patients who underwent lymphangiography for prolonged lymphatic leak following urological surgery. Contrast material is injected slowly into a lymphatic vessel on the dorsum of the foot and serial imaging is used to capture the location and degree of lymphatic leak in order to guide definitive treatment. Demographic and clinical details were collected and are reported.
    Results: Three patients were identified from 2005-2008 (one following donor nephrectomy and two… More >

  • Open Access

    ARTICLE

    Late toxicity rates following definitive radiotherapy for prostate cancer

    Nitin Ohri, Adam P. Dicker, Timothy N. Showalter

    Canadian Journal of Urology, Vol.19, No.4, pp. 6373-6380, 2012

    Abstract Introduction: Most patients survive many years following external beam radiotherapy (RT) for nonmetastatic prostate cancer and are therefore at risk for late treatment sequelae. The relationships between RT dose, treatment technique, and late toxicity rates are incompletely understood. Here we perform a meta-analysis and systematic review to characterize those effects.
    Materials and methods: We performed a review of published series that report late gastrointestinal (GI) and genitourinary (GU) toxicity rates following definitive RT for prostate cancer using the RTOG Late Radiation Morbidity Scoring Schema. Univariate analyses were performed to test RT technique, RT dose, pelvic irradiation, and… More >

  • Open Access

    RESIDENT’S CORNER

    A rare case of solitary metastatic non-seminomatous malignant germ cell tumor to the prostate

    Ryan W. Dobbs1, Adeboye O. Osunkoya1,2, Peter T. Nieh1, Daniel J. Canter1

    Canadian Journal of Urology, Vol.19, No.5, pp. 6471-6473, 2012

    Abstract Testicular cancer is the most common solid malignancy of men aged 15-40 years and metastasizes in a predictable manner via lymphatic spread. Involvement of metastatic testicular cancer to the prostate is an exceedingly rare event which has only been previously described in patients with seminomatous germ cell tumors. In this report, we present a case of a 42-year-old man who presented with metastatic testicular cancer to the prostate 8 years after his original diagnosis of a mixed germ cell left testicular tumor. More >

  • Open Access

    ARTICLE

    VISCOUS DISSIPATION EFFECTS ON THE LIMITING VALUE OF NUSSELT NUMBERS FOR A SHEAR DRIVEN FLOW BETWEEN TWO ASYMMETRICALLY HEATED PARALLEL PLATES

    Pranab Kumar Mondal*, Sanchayan Mukherjee

    Frontiers in Heat and Mass Transfer, Vol.3, No.3, pp. 1-6, 2012, DOI:10.5098/hmt.v3.3.3004

    Abstract The present paper deals with the analytical investigation for the limiting value of Nusselt number, including the effect of viscous dissipation on heat transfer for a laminar shear driven flow between two infinite parallel plates, where the bottom plate is fixed and the top plate is moving in an axial direction at a constant speed. The study concentrates on hydro-dynamically fully developed flow of a Newtonian fluid of constant properties without considering the axial conduction in the fluid. To investigate the effect of viscous dissipation on heat transfer by defining the limiting Nusselt number, plates… More >

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