Katia Boniface1, Jean-Claude Lecron1, François-Xavier Bernard2, Guy Dagregorio3, Gérard Guillet4, François Nau1, Franck Morel1
European Cytokine Network, Vol.16, No.4, pp. 309-319, 2005
Abstract Cytokines are key factors in the cross talk between the immune system and other systems including
hepatic, nervous, cardiac and cutaneous systems, leading to an adaptive and integrated response of the organism
to stress. They are also involved in the regulation of many processes, including hematopoiesis, the immune
response and inflammation. IL-10 is one of the most important anti-inflammatory cytokines. Five cytokines
structurally related to IL-10 have been described and presently form this family of cytokines: IL-19, IL-20, IL-22,
IL-24 and IL-26. In contrast to IL-10, these cytokines display pro-inflammatory activities in different tissues,
including More >