RAFAEL SCAF DE MOLON^1,2,*, ERICA DORIGATTI DE AVILA², JONI AUGUSTO CIRELLI², JOAO PAULO STEFFENS³

BIOCELL, Vol.46, No.3, pp. 633-638, 2022, DOI:10.32604/biocell.2022.018031 - 18 November 2021

Abstract The periodontium comprises all structures surrounding the teeth, including gingiva, root cementum, periodontal ligament and alveolar bone. Those tissues aim to protect and support the teeth and are challenged by a residing microbiota that leads to subclinical inflammation even in physiological conditions. Periodontitis, a prevalent multicausal inflammatory and destructive disease, develops as a result from complex host-parasite interactions. This unique physiologic and pathologic scenario enables the development of research methods which allows conclusions beyond the simple understanding of periodontal homeostasis. The aim of this viewpoint was to explore potential contributions of periodontal research to a More >

Xin Zhang¹, He Nan¹, Jialong Guo¹, Jinyu Liu²

European Cytokine Network, Vol.32, No.2, pp. 15-22, 2021, DOI:10.1684/ecn.2021.0465

Abstract Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by abnormal synovial hyperplasia and the release of inflammatory cytokines. NLRP12 is a member of the family nod-like receptor (NLR) families that are activators of inflammation. However, the role of NLRP12 in fibroblast-like synoviocytes (FLSs) is still unclear. In the present study, we have investigated the role of NLRP12 in fibroblast-like synoviocytes (FLSs). The results demonstrated that NLRP12 overexpression inhibited proliferation and promoted cell apoptosis in RA-FLSs. Moreover, NLRP12 overexpression repressed inflammation by downregulation of IL-1β, TNF-α, IL-6, IFN-γ and MCP-1 production and upregulation of More >

Sara Ibrahim Taha¹, Sara Farid Samaan², Rehab Ali Ibrahim³, Eman Mousa El-Sehsah⁴, Mariam Karam Youssef⁵

European Cytokine Network, Vol.32, No.4, pp. 83-88, 2021, DOI:10.1684/ecn.2021.0471

Abstract Background: Various musculoskeletal and autoimmune manifestations have been described in patients with coronavirus disease 2019 (COVID-19). Objectives: This study aims to investigate the prevalence and etiology of arthritis in post-COVID Egyptian patients. Methods: We included 100 post-COVID Egyptian patients who recovered 6 months ago and assessed several inflammatory and autoimmune markers. Results: The prevalence of post-COVID arthritis was 37%. Ankle, knee, and wrist were the most commonly affected joints. Old age (P = 0.010), smoking (P = 0.001), and arthralgia (P = 0.049) were all linked with post-COVID arthritis. Levels of pretreatment (baseline) interleukin (IL)-6… More >

Dang Quang Hung^1,#, Nguyen-Thi Nhan¹, Trinh-Thi Phuong Nga¹, Nguyen Thanh Hai¹, Nguyen Quang Duc¹, Nguyen Viet Thu¹, Nguyen Truong Duc¹, Dinh-Van Thuyet¹, Nguyen Minh Duc^2,#,*,ORCID

Oncologie, Vol.23, No.4, pp. 603-608, 2021, DOI:10.32604/oncologie.2021.019519 - 31 December 2021

Abstract Metastatic spread of hepatocellular carcinoma (HCC) to the spleen is uncommon, only occurring in approximately 1% of cases. Atraumatic splenic rupture due to HCC metastasis is extremely rare and affects patient prognosis, clinical management, and mortality. We report a case of a 65-year-old man with a history of chronic hepatitis B infection who presented with left-sided abdominal pain and fatigue. Clinical examination showed acute anemia with elevated levels of serum alpha-fetoprotein (AFP) and protein induced by vitamin K absence (PIVKA-II). On ultrasound and computed tomography imaging, hemoperitoneum caused by a ruptured splenic tumor was revealed. More >

Sujeet More¹, Jimmy Singla¹, Oh-Young Song^2,*, Usman Tariq³, Sharaf Malebary⁴

CMC-Computers, Materials & Continua, Vol.69, No.3, pp. 3127-3143, 2021, DOI:10.32604/cmc.2021.018230 - 24 August 2021

Abstract Medical Resonance Imaging (MRI) is a noninvasive, nonradioactive, and meticulous diagnostic modality capability in the field of medical imaging. However, the efficiency of MR image reconstruction is affected by its bulky image sets and slow process implementation. Therefore, to obtain a high-quality reconstructed image we presented a sparse aware noise removal technique that uses convolution neural network (SANR_CNN) for eliminating noise and improving the MR image reconstruction quality. The proposed noise removal or denoising technique adopts a fast CNN architecture that aids in training larger datasets with improved quality, and SARN algorithm is used for More >

Yun-Jung Choi^1,#, Eun-jung Ko^2,#, Eun-Joo Choi^2,*, Youn-Joo Um^2,*

International Journal of Mental Health Promotion, Vol.23, No.3, pp. 385-393, 2021, DOI:10.32604/IJMHP.2021.015018 - 23 July 2021

Abstract This study aims to contribute to improving mental health services and establishing a direction for disaster survivors by verifying the effectiveness of the TLS (Training for Life Skills) app, a mental health management mobile application. Altogether, 22 disaster survivors received access to the app (with guidance) for eight weeks; we analyzed its effectiveness by examining each participant’s electroencephalography data, which were collected while they were utilizing the app. The results of this study show that the use of the TLS app had a significant positive effect on emotional quotient, basic rhythm quotient (left brain, right More >

Chaoxin Jiang^*

International Journal of Mental Health Promotion, Vol.23, No.2, pp. 231-242, 2021, DOI:10.32604/IJMHP.2021.015253 - 30 April 2021

Abstract Traumatic events have been considered significant risk factors for older adults’ mental health, but the mediating mechanism and moderating effect of aging attitudes that underlie this relationship have yet been completely investigated. The attitudes of the elderly toward aging can be divided into two closely related but conceptually different dimensions, including positive and negative. Positive aging attitudes refer to optimistic feelings and experiences about aging, whereas negative attitudes toward aging are related to detrimental thoughts and sensations experienced about the increasing age. The purpose of this study is to explore the mediating and moderating roles More >

Yanpu Chao¹, Hao Yi^2,3,*

FDMP-Fluid Dynamics & Materials Processing, Vol.17, No.3, pp. 587-595, 2021, DOI:10.32604/fdmp.2021.015478 - 29 April 2021

Abstract Many liquid metals have a high boiling point, strong electrical conductivity, high thermal conductivity, and non-toxic properties, which make them ideal targets for applications in different fields such as optics, microcircuits, electronic switches, micro-electromechanical System (MEMS) devices and 3D printing manufacturing. However, owing to the generally high surface tension of these liquids, achieving uniform micro-droplets is often a challenge due to the inherent difficulties in controlling their size and shape. In this study, a gallium indium alloy (GaIn_24.5) has been used in combination with a pneumatic drop-on-demand (DOD) injection technology to carry out a series of More >

ZHIPING WEI^1,2, YAJUN LIU¹, MEIWEN YANG³, MENGDI LI¹, KEXIN LI¹, LUXI ZHENG¹, HUIQIONG GUO¹, FENFANG HONG^4,*, SHULONG YANG^1,*

BIOCELL, Vol.45, No.4, pp. 1005-1012, 2021, DOI:10.32604/biocell.2021.014581 - 22 April 2021

Abstract Background and Objective: LTB4 has been shown to be involved in rheumatoid arthritis (RA) pathogenesis. The effect of Dioscin(Dio) on the LTB4 pathway of RA have not been reported yet. This study aimed at further exploring whether Dioscin’s effects on TNF-α induced collagen-induced arthritis (CIA) rat fibroblast-like synoviocytes (FLS) connected with the LTB4 and its receptor pathway. Materials & Methods: In this experiment, control group, TNF-α group, and different concentrations of Dioscin groups were established. Cell viability was evaluated using MTT assay. The levels of LTB4 in the samples of above groups were measured using ELISA.… More >

Jindan Lyu¹, Longdi Cheng^1,*, Bugao Xu^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.127, No.2, pp. 737-751, 2021, DOI:10.32604/cmes.2021.015153 - 19 April 2021

Abstract Compact spinning with pneumatic grooves is a spinning process to gather fibers by blended actions of airflow and mechanical forces. Modified from the ring spinning system, the lateral compact spinning with pneumatic grooves can improve yarn appearance and properties due to generated additional twists. In this study, we investigated additional twists of the lateral compact spinning with pneumatic grooves via a finite element (FE) method. An elastic thin rod was used to model a fiber to simulate its dynamic deformation in the three-dimensional space, and the space bar unit was used to simplify the fiber… More >