Waruna Seneviratne¹, John Tomblin², Suranga Gunawardana³

The International Conference on Computational & Experimental Engineering and Sciences, Vol.4, No.2, pp. 81-86, 2007, DOI:10.3970/icces.2007.004.081

Abstract An experimental study was conducted to investigate the use of fracture mechanics to predict failure initiation of adhesive joints. Most practical plane fracture problems are mixed mode and failure initiation of adhesive joints is a result of such conditions. It is widely accepted that a useful method for characterizing the toughness of bonded joints is to measure the fracture toughness; energy per unit area needed to produce failure. For a given adhesive, mode mixity has a dependency towards fracture toughness and fracture toughness is directly associated with stress. Main goal in this investigation was to… More >

L. Roy Xu¹, Charles M. Lukehart², Lang Li², Huacheng Kuai¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.3, No.1, pp. 9-14, 2007, DOI:10.3970/icces.2007.003.009

Abstract Graphitic carbon nanofibers were used to reinforce epoxy resin to form nanocomposite adhesive bonding. Good dispersion and polymer wetting of the GCNF component is evident on the nanoscale. Tensile and shear joint strength measurements were conducted for metal-metal and polymer-polymer joints using pure epoxy and nanocomposite bonding. Very little bonding strength increase, or some bonding strength decrease, was measured. More >

Wendong Shi^∗,†, Xi-Qiao Feng^*, Huajian Gao^†

Molecular & Cellular Biomechanics, Vol.3, No.3, pp. 121-126, 2006, DOI:10.3970/mcb.2006.003.121

Abstract When pulling a vesicle adhered on a substrate, both the force-displacement profile and the maximum force at pull-off are sensitively dependent upon the substrate shape. Here we consider the adhesion between a two-dimensional vesicle and a rigid substrate via long-range molecular interactions. For a given contact area, the theoretical pull-off force of the vesicle is obtained by multiplying the theoretical strength of adhesion and the contact area. It is shown that one may design an optimal substrate shape to achieve the theoretical pull-off force. More >

Guanbin Song^∗,†, Toshiro Ohashi^†, Naoya Sakamoto^†, Masaaki Sato^†

Molecular & Cellular Biomechanics, Vol.3, No.2, pp. 61-68, 2006, DOI:10.3970/mcb.2006.003.061

Abstract Expression of adhesion molecules may play an important role in the interaction of tumor cells with vascular endothelial cells during tumor invasion and metastasis. In this study, the adhesive force of human hepatoma HepG2 cells to human umbilical vein endothelial cells (HUVECs) was investigated using a micropipette aspiration technique. Expression of an adhesion molecule, E-selectin, was also observed by immunofluorescence microscopy. In particular, the adhesive force after stimulation of HUVECs with recombinant human interleukin-1β (rhIL-1β) was examined. The results demonstrated that the adhesive force of HepG2 cells to stimulated HUVECs is significantly higher than that More >