Marta Suárez-Santamaría1, Francisco Santolaria2, Alina Pérez-Ramírez2, María-Remedios Alemán-Valls2, Antonio Martínez-Riera2, Emilio González-Reimers2, María-José de la Vega1, Antonio Milena1
European Cytokine Network, Vol.21, No.1, pp. 19-26, 2010, DOI:10.1684/ecn.2009.0185
Abstract Objective. Procalcitonin is useful for the diagnosis of sepsis, but its prognostic value regarding
mortality is unclear. Our objective was to determine the prognostic value of procalcitonin determined at the
onset of sepsis, and to compare it with other markers of inflammatory response, malnutrition and organ dys-function
data. Methods. We studied 253 hospitalized patients (146 men, 107 women) with a median age of 65
years. Sepsis was defined as infection, and at least two SIRS criteria. We assessed co-morbidities, nutritional
status, bacteremia, procalcitonin and other inflammatory markers (PCR, TNF-α, IL6, TREM-1, IL-10, IL-1ra,
CD14 and… More >