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  • Open Access

    ARTICLE

    Management of benign prostatic hyperplasia by the primary care physician in the 21st century: the new paradigm

    Jack Barkin

    Canadian Journal of Urology, Vol.15, Suppl.4, pp. 21-30, 2008

    Abstract Benign prostatic hyperplasia (BPH) is one of the commonest causes of lower urinary tract symptoms (LUTS) in men over age 50. Fifty percent of men over age 50 will require some type of management for BPH/LUTS symptoms. Until about 15 years ago, the most common management for BPH was a transurethral resection of the prostate (TURP) operation. Initially, once a diagnosis of BPH has been made, most men are treated medically. One must fi rst rule out other serious causes of these symptoms, such as prostate cancer, bladder cancer, and other obstructions. For men with… More >

  • Open Access

    ARTICLE

    Management of symptomatic benign prostatic hyperplasia-today

    Jack Barkin

    Canadian Journal of Urology, Vol.15, No.6, pp. 4353-4358, 2008

    Abstract Symptomatic benign prostatic hyperplasia (BPH) is one of the commonest causes of men presenting with lower urinary tract symptoms (LUTS). We can fi nd this in 50% of men over the age of fi fty. If BPH is not treated, then one can expect that the disease will progress in a signifi cant number of individuals. What we need to do is try to predict, based on certain baseline parameters such as International Prostate Score (IPSS), prostate volume, prostate-specifi c antigen (PSA) and the degree of bother, those men to whom we should offer therapy. More >

  • Open Access

    ARTICLE

    Effects of Heat Affected Zones Temperature on the General Performance of High Temperature Vacuum Tube Furnace

    A.B. Mahmud Hasan1,2, M A Wahab1, S.M. Guo1

    Structural Durability & Health Monitoring, Vol.4, No.4, pp. 231-240, 2008, DOI:10.3970/sdhm.2008.004.231

    Abstract This paper presents details analysis of Heat Affected Zone (HAZ) in High Temperature Vacuum Tube Furnace (HTVTF) to predict fracture region in tube wall due to thermal stress from temperature variation across its thickness. A simple mathematical model is used to illustrate stress concentration arising due to thermal stresses in tube wall and HAZs. Finite element model and analysis were carried out utilizing finite element analysis commercial codes. Combination of thermal stress due to temperature difference determine fracture region. Experimental and simulation results of inside temperature of tube are observed and similar relation have been More >

  • Open Access

    ARTICLE

    Fluid Transport in Compacted Porous Talc Blocks

    Viveca Wallqvist1, Per M. Claesson2, Agne Swerin1, Patrick A. C. Gane3,4,3, Joachim Schoelkopf3

    FDMP-Fluid Dynamics & Materials Processing, Vol.4, No.2, pp. 85-98, 2008, DOI:10.3970/fdmp.2008.004.085

    Abstract It has been shown that talc powder can be compacted into tablets with a preferred orientation of the platelets. The tablets can be obtained with different controlled porosity depending on pressing methods and applied pressure. The tablets can be obtained with or without additives, which may, in turn, be adsorbed. The orientation of the high aspect ratio platy talc, the surface chemistry imparted by the additives and the transported fluid influence the imbibition and permeation rates. Non-polar hexadecane displays a higher imbibition and permeability than water for all particulate orientations during short timescale absorption, likely… More >

  • Open Access

    ARTICLE

    TNF triggers mitogenic signals in NIH 3T3 cells but induces apoptosis when the cell cycle is blocked

    René Rodríguez1, Victor M. Campa1, José Riera1, M. Teresa Carcedo1, David S. Ucker2, Sofía Ramos1, Pedro S. Lazo1

    European Cytokine Network, Vol.18, No.4, pp. 172-180, 2007, DOI:10.1684/ecn.2007.0106

    Abstract Tumor necrosis factor (TNF) is known to be a mediator of a variety of cellular responses including apoptotic death or proliferation depending on the target cell and the environmental conditions. We show here that TNF triggers both growth and death signals in NIH 3T3 murine fibroblasts. In cells arrested in G0 by serum deprivation, TNF drives approximately 50% of them to enter the cell cycle, but kills the cells that remain quiescent. The presence of serum prevents toxic effects of TNF, suggesting that TNF can cooperate to drive cells through the cell cycle, but is unable… More >

  • Open Access

    ARTICLE

    TNF triggers mitogenic signals in NIH 3T3 cells, but induces apoptosis when the cell cycle is blocked

    René Rodríguez1, Victor M. Campa1, José Riera1, M. Teresa Carcedo1, David S. Ucker2, Sofía Ramos1, Pedro S. Lazo1

    European Cytokine Network, Vol.18, No.4, pp. 23-31, 2007, DOI:10.1684/ecn.2007.0106

    Abstract Tumor necrosis factor (TNF) is known to be a mediator of a variety of cellular responses including apoptotic death or proliferation depending on the target cell and the environmental conditions. We show here that TNF triggers both growth and death signals in NIH3T3 murine fibroblasts. In cells arrested in G0 by serum deprivation, TNF drives approximately 50% of them to enter the cell cycle, but kills the cells that remain quiescent. The presence of serum prevents toxic effects of TNF, suggesting that TNF can cooperate to drive cells through the cell cycle, but is unable… More >

  • Open Access

    ARTICLE

    Effect of Nitriding Treatment on Fatigue life for Free Piston Linear Engine Component using Frequency Response Method: a Finite Element Approach

    M. M. Rahman1, A. K. Ariffin2, S. Abdullah2, A. B. Rosli1

    Structural Durability & Health Monitoring, Vol.3, No.4, pp. 197-210, 2007, DOI:10.3970/sdhm.2007.003.197

    Abstract Low weight and long lifetime are necessary requirements for automobiles to significantly reduce CO2 emission and environmental burdens in their use. Aluminum alloys are one of the most promising materials selections for automobiles parts and electrical components to reduce their weight and to increase their specific strength. This paper presents the role of nitriding on the fatigue life of the vibrating cylinder block for a new two-stroke free piston engine using variable amplitude loading conditions. The finite element modeling and analysis have been performed utilising a computer aided design and a finite element analysis codes respectively.… More >

  • Open Access

    ABSTRACT

    Probabilistic Neural Network for Predicting the Stability numbers of Breakwater Armor Blocks

    Doo Kie Kim1, Dong Hyawn Kim2, Seong Kyu Chang1, Sang Kil Chang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.2, No.2, pp. 35-40, 2007, DOI:10.3970/icces.2007.002.035

    Abstract The stability numbers determining the Armor units are very important to design breakwaters, because armor units are designed for defending breakwaters from repeated wave loads. This study presents a probabilistic neural network (PNN) for predicting the stability number of armor blocks of breakwaters. PNN used the experimental data of van der Meer as train and test data. The estimated results of PNN were compared with those of empirical formula and previous artificial neural network (ANN) model. The comparison results showed the efficiency of the proposed method in the prediction of the stability numbers in spite More >

  • Open Access

    ARTICLE

    Block Stratification of Sedimenting Granular Matter in a Vessel due to Vertical Vibrations

    V.G. Kozlov1,2, A.A. Ivanova3, P. Evesque1

    FDMP-Fluid Dynamics & Materials Processing, Vol.2, No.3, pp. 203-210, 2006, DOI:10.3970/fdmp.2006.002.203

    Abstract Sedimentation of granular matter in a vertical channel filled with a viscous liquid and subject to longitudinal translational vibration is studied, starting froma compact suspension. A new vibrational effect is foundexperimentally and described theoretically; it is the formation of blocks (with a relatively high density) of sedimenting granular matter with stable lower and upper horizontal demarcations and a sharp density discontinuity. Owing to this phenomenon the sedimentation velocity of such granular matter is reduced. A new theoreticalmodel based on viscous vibrational particle interactionin the limit of concentrated suspensions is elaborated, assuming particle-particle attraction in direction More >

  • Open Access

    ARTICLE

    A Parallel Multi-block Method for the Unsteady Vorticity-velocity Equations

    A. Grimaldi1, G. Pascazio2, M. Napolitano3

    CMES-Computer Modeling in Engineering & Sciences, Vol.14, No.1, pp. 45-56, 2006, DOI:10.3970/cmes.2006.014.045

    Abstract This paper provides a numerical method for solving two- and three-dimensional unsteady incompressible flows. The vorticity-velocity formulation of the Navier--Stokes equations is considered, employing the vorticity transport equation and a second-order Poisson equation for the velocity. Second-order-accurate centred finite differences on a staggered grid are used for the space discretization. The vorticity equation is discretized in time using a fully implicit three-level scheme. At each physical time level, a dual-time stepping technique is used to solve the coupled system of non linear algebraic equations by various efficient relaxation schemes. Steady flows are computed by dropping More >

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