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  • Open Access


    Early-Stage Cervical Cancerous Cell Detection from Cervix Images Using YOLOv5

    Md Zahid Hasan Ontor1, Md Mamun Ali1, Kawsar Ahmed2,3,*, Francis M. Bui3, Fahad Ahmed Al-Zahrani4, S. M. Hasan Mahmud5, Sami Azam6

    CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 3727-3741, 2023, DOI:10.32604/cmc.2023.032794

    Abstract Cervical Cancer (CC) is a rapidly growing disease among women throughout the world, especially in developed and developing countries. For this many women have died. Fortunately, it is curable if it can be diagnosed and detected at an early stage and taken proper treatment. But the high cost, awareness, highly equipped diagnosis environment, and availability of screening tests is a major barrier to participating in screening or clinical test diagnoses to detect CC at an early stage. To solve this issue, the study focuses on building a deep learning-based automated system to diagnose CC in the early stage using cervix… More >

  • Open Access


    A Review of the Role of ERp57 in Cancerous and Non-Cancerous Cell Physiology and its Potential as a Therapeutic Target

    Fatemeh Rahbar1, Avid Farhang Fagheh2, Ayda Khosravi2, Siavash Shariatzadeh2,3,*, Reza Akhavan-Sigari4

    Molecular & Cellular Biomechanics, Vol.18, No.4, pp. 187-199, 2021, DOI:10.32604/mcb.2021.017750

    Abstract The protein ERp57 is a stress-responsive protein, mainly exists in the endoplasmic reticulum (ER), and a small amount in the cell membrane, cytoplasm, nucleus and mitochondria, which is involved in the signal transduction from the cell surface, the regulation process that occurs in the nucleus, and the formation of polymer protein complexes involved in DNA repair. Various degrees of ERp57 dysregulation has been observed in many types of non-communicable diseases especially in cancers. Previous studies showed that the expression of ERp57 could play a key role in occurrence and development of cancers such as breast cancer, gastric cancer, ovarian cancer,… More >

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