John K. A. Tetteh¹, Mark M. Addae¹, Naruhiko Ishiwada², Sena M. Yempewu¹, Shinya Yamaguchi¹, David Ofori-Adjei¹, Hitoshi Kamiya⁴, Yoshihiro Komada³, Bartholomew D. Akanmori^1,*

European Cytokine Network, Vol.14, No.2, pp. 109-113, 2003

Abstract To understand the pathogenesis of vaccine-modified measles (VMM), we measured plasma levels of IFN-γ and IL-2 (Th1 cytokines), IL-4 and IL-10 (Th2 cytokines), IL-12, TNF-α and TGF-β1 in children with uncomplicated measles, who had anti-measles IgG antibodies and with a history of immunization on admission (day 0), day 14 and day 60. We compared these to levels in healthy, age-matched, immunized children. Plasma levels of IFN-γ, IL-2 and IL-12 were significantly higher in VMM patients on day 0 compared to healthy controls (p = 0.023; p = 0.018; p = 0.001) respectively. In contrast, plasma… More >

Saadou Issifou¹, Elie Mavoungou^1,2, Steffen Borrmann^1,2, Marielle K. Bouyou-Akotet¹, Pierre-Blaise Matsiegui^1,2, Peter G. Kremsner^1,2, Francine Ntoumi^1,2

European Cytokine Network, Vol.14, No.4, pp. 238-241, 2003

Abstract To investigate if severe malarial anemia is associated with specific cytokine overproduction, we evaluated serum levels of soluble Fas ligand (sFasL), tumor necrosis factor (TNF-α) and interleukin-10 (IL-10) from three groups of young children with Plasmodium falciparum infection (asymptomatic cases, uncomplicated malaria cases and severe malarial anemia cases), in a hyperendemic area of Gabon. In uncomplicated cases, only TNF levels were significantly (p < 0.001) increased in comparison to asymptomatic cases with P. falciparum infection. High levels of sFasL, TNF-α and IL-10 were associated with low hemoglobin concentrations, sFasL levels were significantly higher in children with severe More >

Daniel J. Caruso, Murali K. Ankem, John Riordan, Joseph G. Barone

Canadian Journal of Urology, Vol.10, No.3, pp. 1910-1911, 2003

Abstract Prune Belly Syndrome developed urinary ascites secondary to forniceal rupture. Treatment consisted of bilateral cutaneous pyelostomies. Even though most children with Prune Belly Syndrome respond to lower urinary tract drainage, a cutaneous pyelostomy may be necessary when the ureters are tortuous and do not drain adequately following bladder decompression. More >

Gordon A. McLorie³, Jeff Pugach³, Dov Pode², John Denstedt⁴, Darius Bagli³, Shimon Meretyk², R. John D’A Honey⁴, Paul A. Merguerian³, Amos Shapiro², Antoine E. Khoury³, Ezekiel H. Landau¹

Canadian Journal of Urology, Vol.10, No.6, pp. 2051-2055, 2003

Abstract Purpose: Extracorporeal shock wave lithotripsy (ESWL) in older children appears to have comparable results when compared to adults, no study has focused on its use in younger children. We reviewed our ESWL experience in children under age 3.5 years to evaluate its safety, and define optimal treatment parameters.
Methods: We retrospectively reviewed consecutive medical and diagnostic imaging records from three ESWL centers, pertaining to 34 children under 3.5 years of age (36 renal units-RU). The children were from two distinct populations served exclusively by the three centers. We analyzed patient presentation, etiology, age, weight, stone size, preoperative… More >

Steven P. Lapointe, Anne-Marie Houle, Diego Barrieras

Canadian Journal of Urology, Vol.9, No.5, pp. 1651-1652, 2002

Abstract Laparoscopy has greatly evolved over the years. More recently, retroperitoneoscopy has gained wide acceptance as the preferred approach for simple and complicated nephrectomies. We report on a 12 year-old girl who underwent a left nephrectomy on a horseshoe kidney through a retroperitoneoscopic approach using the harmonic scalpel for dissection and isthmus division. The operation was successful, recovery uneventful, and the patient was discharged 24 hrs post operatively, with excellent cosmesis. Retroperitoneoscopy can be considered if ablative surgery is contemplated in a horseshoe kidney, with adequate preoperative evaluation and solid retroperitoneoscopic surgical experience. The use the More >