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  • Open Access

    ARTICLE

    In vitro polymerization of the dopamine-borate melanin precursor: A proof-of-concept regarding boron neutron-capture therapy for melanoma

    JUAN C. STOCKERT1,2,*, SILVINA A. ROMERO1, MARCELO N. FELIX-POZZI3, ALFONSO BLÁZQUEZ-CASTRO4

    BIOCELL, Vol.47, No.4, pp. 919-928, 2023, DOI:10.32604/biocell.2023.026631 - 08 March 2023

    Abstract

    The 10boron neutron-capture therapy (BNCT) is an emerging antitumoral method that shows increasing biomedical interest. BNCT is based on the selective accumulation of the 10boron isotope within the tumor, which is then irradiated with low-energy thermal neutrons, generating nuclear fission that produces 7lithium, 4helium, and γ rays. Simple catechol-borate esters have been rather overlooked as precursors of melanin biosynthesis, and therefore, a proof-of-concept approach for using dopamine-borate (DABO) as a suitable boron-containing candidate for potential BNCT is presented here. DABO can spontaneously oxidize and autopolymerize in vitro, giving a soluble, eumelanin-like brown-black poly-DABO product. Melanotic melanoma cell cultures treated

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  • Open Access

    ARTICLE

    Combined Effect of Concept Drift and Class Imbalance on Model Performance During Stream Classification

    Abdul Sattar Palli1,6,*, Jafreezal Jaafar1,2, Manzoor Ahmed Hashmani1,3, Heitor Murilo Gomes4,5, Aeshah Alsughayyir7, Abdul Rehman Gilal1

    CMC-Computers, Materials & Continua, Vol.75, No.1, pp. 1827-1845, 2023, DOI:10.32604/cmc.2023.033934 - 06 February 2023

    Abstract Every application in a smart city environment like the smart grid, health monitoring, security, and surveillance generates non-stationary data streams. Due to such nature, the statistical properties of data changes over time, leading to class imbalance and concept drift issues. Both these issues cause model performance degradation. Most of the current work has been focused on developing an ensemble strategy by training a new classifier on the latest data to resolve the issue. These techniques suffer while training the new classifier if the data is imbalanced. Also, the class imbalance ratio may change greatly from… More >

  • Open Access

    ARTICLE

    Drift Detection Method Using Distance Measures and Windowing Schemes for Sentiment Classification

    Idris Rabiu1,3,*, Naomie Salim2, Maged Nasser1,4, Aminu Da’u1, Taiseer Abdalla Elfadil Eisa5, Mhassen Elnour Elneel Dalam6

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 6001-6017, 2023, DOI:10.32604/cmc.2023.035221 - 28 December 2022

    Abstract Textual data streams have been extensively used in practical applications where consumers of online products have expressed their views regarding online products. Due to changes in data distribution, commonly referred to as concept drift, mining this data stream is a challenging problem for researchers. The majority of the existing drift detection techniques are based on classification errors, which have higher probabilities of false-positive or missed detections. To improve classification accuracy, there is a need to develop more intuitive detection techniques that can identify a great number of drifts in the data streams. This paper presents… More >

  • Open Access

    ARTICLE

    Seismic Liquefaction Resistance Based on Strain Energy Concept Considering Fine Content Value Effect and Performance Parametric Sensitivity Analysis

    Nima Pirhadi1, Xusheng Wan1, Jianguo Lu1, Jilei Hu2,3,*, Mahmood Ahmad4,5, Farzaneh Tahmoorian6

    CMES-Computer Modeling in Engineering & Sciences, Vol.135, No.1, pp. 733-754, 2023, DOI:10.32604/cmes.2022.022207 - 29 September 2022

    Abstract Liquefaction is one of the most destructive phenomena caused by earthquakes, which has been studied in the issues of potential, triggering and hazard analysis. The strain energy approach is a common method to investigate liquefaction potential. In this study, two Artificial Neural Network (ANN) models were developed to estimate the liquefaction resistance of sandy soil based on the capacity strain energy concept (W) by using laboratory test data. A large database was collected from the literature. One group of the dataset was utilized for validating the process in order to prevent overtraining the presented model. To… More >

  • Open Access

    ARTICLE

    La genèse systémique d’empreinte pour une maîtrise de l’observation de la Terre

    Mireille Fargette1 , Maud Loireau2, Najet Raouani3 , Thérèse Libourel4

    Revue Internationale de Géomatique, Vol.31, No.1, pp. 135-197, 2022, DOI:10.3166/RIG31.135-197

    Abstract Ce travail s’intéresse à l’observation, à la connaissance scientifique construite à partir de ce qui est perçu (Lien de Sens) d’un monde systémique complexe. La démarche conduit à proposer le concept d’empreinte dans le cadre scientifique interdisciplinaire « Système - Réalité - Monde perçu - Modèle », à le mettre à l’épreuve des données, puis à proposer la démarche d’ontologie systémique. Celle-ci permet de déployer le Lien de Forme du domaine systémique au monde perçu, d’analyser et décrire la part pertinente de la donnée et de montrer en quoi l’ensemble de ce travail essentiellement symbolique More >

  • Open Access

    ARTICLE

    RESEARCH ON A NOVEL CONCEPT OF SELF-FORMING AIR COOLING BATTERY RACK

    Mingjie Zhanga , Kai Yanga, Le Qinb, Xiaole Yaob, Qian Liub, Xing Jub,*

    Frontiers in Heat and Mass Transfer, Vol.19, pp. 1-10, 2022, DOI:10.5098/hmt.19.13

    Abstract Lithium-ion batteries used for energy storage systems will release amount of heat during operation. It will cause serious consequences of thermal runaway if not dissipate in time. In this study, a self-forming air-cooled battery rack of the energy storage system is established based on the normal battery rack for energy storage and the shape of the energy storage battery itself. The frames of the battery rack acts as air ducts, which greatly reduce the system complexity. In this paper, the heat generation model is established based on the experiment, and the four battery rack forms… More >

  • Open Access

    ARTICLE

    Trustworthy Explainable Recommendation Framework for Relevancy

    Saba Sana*, Mohammad Shoaib

    CMC-Computers, Materials & Continua, Vol.73, No.3, pp. 5887-5909, 2022, DOI:10.32604/cmc.2022.028046 - 28 July 2022

    Abstract Explainable recommendation systems deal with the problem of ‘Why’. Besides providing the user with the recommendation, it is also explained why such an object is being recommended. It helps to improve trustworthiness, effectiveness, efficiency, persuasiveness, and user satisfaction towards the system. To recommend the relevant information with an explanation to the user is required. Existing systems provide the top-k recommendation options to the user based on ratings and reviews about the required object but unable to explain the matched-attribute-based recommendation to the user. A framework is proposed to fetch the most specific information that matches More >

  • Open Access

    ARTICLE

    Multi-Layer and Multi-Objective Optimization Design of Supporting Structure of Large-Scale Spherical Solar Concentrator for the Space Solar Power Station

    Yang Yang, Jun Hu, Lin Zhu*, Mengchen Pei

    Journal of Renewable Materials, Vol.10, No.11, pp. 2835-2849, 2022, DOI:10.32604/jrm.2022.021840 - 29 June 2022

    Abstract Space solar power station is a novel renewable energy equipment in space to provide the earth with abundant and continuous power. The Orb-shaped Membrane Energy Gathering Array, one of the alternative construction schemes in China, is promising for collecting space sunlight with a large-scale spherical concentrator. Both the structural and optical performances such as root mean square deformation, natural frequency, system mass, and sunlight blocking rate have significant influences on the system property of the concentrator. Considering the comprehensive performance of structure and optic, this paper proposes a novel mesh grid based on normal polyhedron… More > Graphic Abstract

    Multi-Layer and Multi-Objective Optimization Design of Supporting Structure of Large-Scale Spherical Solar Concentrator for the Space Solar Power Station

  • Open Access

    ARTICLE

    Group Decision-Making Method with Incomplete Intuitionistic Fuzzy Preference Relations Based on a Generalized Multiplicative Consistent Concept

    Xiaoyun Lu1, Jiuying Dong2,3,*, Hecheng Li1, Shuping Wan4

    CMES-Computer Modeling in Engineering & Sciences, Vol.132, No.3, pp. 881-907, 2022, DOI:10.32604/cmes.2022.020598 - 27 June 2022

    Abstract Based on the analyses of existing preference group decision-making (PGDM) methods with intuitionistic fuzzy preference relations (IFPRs), we present a new PGDM framework with incomplete IFPRs. A generalized multiplicative consistent for IFPRs is defined, and a mathematical programming model is constructed to supplement the missing values in incomplete IFPRs. Moreover, in this study, another mathematical programming model is constructed to improve the consistency level of unacceptably multiplicative consistent IFPRs. For group decisionmaking (GDM) with incomplete IFPRs, three reliable sources inuencing the weights of experts are identified. Subsequently, a method for determining the weights of experts More >

  • Open Access

    ARTICLE

    Conceptual Modeling and Simulation Application Analysis of In-service Assessment

    Jian-Hua Luo1, Xi Chen1,*, Hua Li1, Yu-Hang Zhou1, Jing-Wen Li2

    Journal of Information Hiding and Privacy Protection, Vol.4, No.1, pp. 53-60, 2022, DOI:10.32604/jihpp.2022.032109 - 17 June 2022

    Abstract Firstly, this paper expounds the conceptual connotation of in-service assessment in the new system, then applies modeling and Simulation in the field of in-service assessment, establishes the conceptual model of in-service assessment and its process, and finally analyzes the application of modeling and simulation in the specific links of in-service assessment. More >

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